M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M20562
|
Dodecanedioic acid |
Dodecanedioic acid is a dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitors, surfactants, and engineering plastics. |
| M20560
|
Indole-2-carboxylic acid |
Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. |
| M20559
|
Brucine sulfate heptahydrate |
Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons. |
| M20557
|
3-Indoleacetonitrile |
3-Indoleacetonitrile, a plant growth hormone, is a light-induced auxin-inhibitory substance that is isolated from light-grown cabbage (Brassica olearea L.) shoots. |
| M20556
|
2,6-Dihydroxybenzoic acid |
2,6-Dihydroxybenzoic acid is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition. |
| M20548
|
2,4-Pyridinedicarboxylic acid |
2,4-Pyridinedicarboxylic acid is a compound that structurally mimics 2-oxoglutarate (2-OG) and chelates zinc, thus affecting a range of enzymes. It blocks the activity of 2-OG oxygenases. |
| M20546
|
D-Carnitine hydrochloride |
Carnitine is biosynthesized from lysine. It might be associated with the energy production from branched chain amino acids. |
| M20542
|
Ethacrynate Sodium |
Ethacrynate Sodium is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. |
| M20534
|
4'-Deoxyphlorizin |
4'-Deoxyphlorizin is an inhibitor of the glucose transport system. |
| M20532
|
Delapril Hydrochloride |
an agonist of the RXR signaling pathway |
| M20531
|
Carvedilol EP IMpurity E |
Used as pharmaceutical intermediates-Intermediates |
| M20525
|
Carvedilol Phosphate |
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. |
| M20523
|
Tropolone |
Tropolone inhibits both mono-and o-dihydroxyphenolase activity of mushroom tyrosinase. |
| M20522
|
Tropinone |
Tropinone is an alkamine intermediate at the branch point of biosynthetic pathways leading to various tropane alkaloids. |
| M20518
|
Orphenadrine Hydrochloride |
A muscarinic receptor antagonist, specifically an H1 histamine receptor antagonist. This compound is a muscle relaxant. Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel. |
| M20512
|
Ammonium lactate |
inhibit nucleocapsid/RNA interactions in Rift Valley Fever Virus |
| M20510
|
Chicago Sky Blue 6B |
A potent inhibitor of L-glutamate uptake via glutamate transporter (EAAT) |
| M20509
|
4,4prime-Bis(4-aminophenoxy)biphenyl |
A potent Flk-1 (VEGFR2) and Tie-2 inhibitor |
| M20508
|
Sulfamide |
Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay |
| M20502
|
H-Cys(Trt)-OH |
H-Cys(Trt)-OH is a specific inhibitor of Eg5 that inhibits Eg5-driven microtubule sliding velocity in a reversible fashion with an IC50 of 500 nM. |
