M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M20499
|
4-Methylsalicylic acid |
4-Methylsalicylic acid 是一种水杨酸，其衍生物是一种选择性的组织-非特异性碱性磷酸酶 (TNAP) 和肠道碱性磷酸酶 (IAP) 抑制剂。 |
| M20497
|
2’-deoxyuridine |
2'-Deoxyuridine is an inhibitor of HSV-1 pyrimidine deoxythymidine kinase using 2-[14C]deoxythymidine as substrate. |
| M20494
|
Cimicifugoside |
Cimicifugoside is a triterpenoid originating from the rhizomes of Cimicifuga simplex, and acts to inhibit the subcellular transport of nucleosides. |
| M20493
|
2-Chloro-1-(4-fluorobenzyl)benzimidazole |
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative. |
| M20491
|
4-Bromo-3-hydroxybenzoic acid |
4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with resultant inhibition of histamine formation in mammals. |
| M20487
|
AS057278 |
AS057278 (3-Methylpyrazole-5-carboxylic acid, MPC) is an inhibitor of D-amino acid oxidase (DAAO). |
| M20480
|
4'-Hydroxypropiophenone |
an inhibitor of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) |
| M20472
|
INCB032304 |
deuterated derivatives of ruxolitinib |
| M20471
|
Suloctidil |
Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent. |
| M20470
|
Doxapram |
Doxapram is a central respiratory stimulant with a brief duration of action. |
| M20469
|
Nicardipine |
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. |
| M20465
|
Diaveridine |
Diaveridine is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis. |
| M20463
|
2,6-Dihydroxyanthraquinone |
Anthraflavic acid (2,6-Dihydroxyanthraquinone) is a potent and specific inhibitor of cytochrome P-448 activity. |
| M20462
|
Benzoyleneurea |
Benzoyleneurea scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors. |
| M20461
|
Gypenoside |
Gypenoside (GP) is the predominant effective component of Gynostemma pentaphyllum and possesses capacities against inflammation and oxidation. |
| M20459
|
Methyl Dihydrojasmonate |
Methyl dihydrojasmonate is a flavouring ingredien with the smell vaguely similar to jasmin. |
| M20456
|
Carbazochrome |
Carbazochrome is a hemostatic agent that causes the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. |
| M20450
|
Methyl α-D-mannopyranoside |
Methyl α-D-mannopyranoside can be used as an intermediate for chemical sythesis and is a competitor inhibitor of the binding of mannose by Escherichia coli. |
| M20446
|
Indobufen |
Indobufen is a reversible platelet aggregation inhibitor. It inhibits the platelet cyclooxygenase enzyme and suppresses thromboxane synthesis. |
| M20444
|
2-Aminobenzenesulfonamide |
2-Aminobenzenesulfonamide is a molecule containing the sulfonamide functional group attached to an aniline |
