M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物,靶向作用于实体瘤的hypoxic区域,IC50为19 nM,在缺氧条件下比在有氧条件下细胞毒性增强270倍,细胞色素P450代谢稳定。 |
M6098
|
Baicalein |
Baicalein(5,6,7-Trihydroxyflavone,Noroxylin,黄芩素)是一种存在于黄芩,木蝴蝶,百里香等植物中的天然黄酮类化合物,具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径,同时也可通过上调GPX4,抑制黑素细胞的铁死亡(ferroptosis),用于白癜风和肿瘤的相关研究。 |
M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂,在生理 pH 值 (7.4) 下,Kd 为 60.5 nM,对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
M9330
|
Brij-35 |
Brij-35(月桂醇聚氧乙烯醚)是一种无毒的非离子表面活性剂,可降低非特定蛋白质的吸附,应用于红曲霉深层发酵时,能显著提高红曲色素产量。 |
M6154
|
2-PMPA tetrasodium |
2-PMPA(PMPA tetrasodium salt)是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂,IC50值为300 pM。 |
M2250
|
Pamidronate disodium |
Pamidronate Disodium(帕米膦酸二钠)是一种含氮的双磷酸盐类化合物,具有抑制骨吸收的作用,可用于癌症相关的溶骨性病变等研究。 |
M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl,2,2-联苯基-1-苦基肼基) 是一种稳定的自由基,可用于测量抗氧化剂的自由基清除活性。 |
M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素,其调节血液中的糖(葡萄糖)水平并且由胰岛的β细胞产生。 |
M3409
|
Formestane |
Formestane(4-hydroxyandrostenedione,福美司坦)是第二代选择性芳香酶抑制剂,IC50为80 nM。 |
M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide(N-acryloyl-glycinamide,丙烯酰基甘氨酰胺)是一种单体,其聚合物能制备水凝胶,并用于酶的固定化。 |
M20163
|
WAY-352835 |
WAY-352835 is a tyrosine kinase inhibitor |
M20160
|
WAY-351783 |
WAY-351783 is a creatin kinase inhibitor. |
M20159
|
WAY-351429 |
WAY-351429 is a choline kinase inhibitor. |
M20158
|
WAY-350732 |
WAY-350732 is a dual inhibitor of the c-Jun N-terminal kinase. |
M20157
|
WAY-349858 |
WAY-349858 is a dual inhibitor of the c-Jun N-terminal kinase. |
M20153
|
WAY-347806 |
WAY-347806 is a dual kinase inhibitor of CK2 and GSK3β |
M20151
|
WAY-347243 |
WAY-347243 is a Mycobacterium tuberculosis shikimate kinase inhibitor. |
M20146
|
WAY-337647 |
WAY-337647 is a inhibitor of mitogen-activated protein kinase kinase 4. |
M20144
|
WAY-333908 |
WAY-333908 is a protein kinase inhibitor. |
M20143
|
WAY-333883 |
WAY-333883 altering the lifespan of a eukaryotic organism |
M20142
|
WAY-333878 |
WAY-333878 altering the lifespan of a eukaryotic organism |
M20141
|
WAY-333875 |
WAY-333875 altering the lifespan of a eukaryotic organism |
M20139
|
WAY-333434 |
WAY-333434 is a inhibitor of protein kinases. |
M20138
|
WAY-330162 |
WAY-330162 has kinase inhibitory activity. |
M20134
|
WAY-329607 |
WAY-329607 has kinase inhibitory activity. |
M20133
|
WAY-329603 |
WAY-329603 has kinase inhibitory activity. |
M20132
|
WAY-329599 |
WAY-329599 has kinase inhibitory activity. |
M20131
|
WAY-329598 |
WAY-329598 has kinase inhibitory activity. |
M20130
|
WAY-329594 |
WAY-329594 has kinase inhibitory activity. |
M20129
|
WAY-329592 |
WAY-329592 has Tyrosine kinase inhibitory activity. |