目录号 | 产品名称 | 产品简介 |
---|---|---|
M4614 | Orientin | Orientin(荭草苷)是一种可从药用植物中分离的生物活性化合物,能有效地抑制Sortase A的活性,其IC50为50.44 ± 0.51 µM。还可以通过Nrf2以及JNK/cytochrome c/caspase-3信号通路,抑制APAP诱导的肝细胞氧化损伤和线粒体功能障碍,具有抗氧化,抗炎和抗癌活性。 |
M9358 | ITE | ITE是一种有效的,内源性的芳烃受体(AhR)的激动剂,可直接与AhR结合,Ki为3 nM。 |
M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) α-半乳糖神经酰胺 是一种强大的NKT细胞刺激剂,和选择性CD1d配体。α-Galactosylceramide (α-GalCer) 是一种合成的糖脂,具有抗肿瘤和免疫刺激作用。 |
M1831 | Cyclosporine A | Cyclosporin A(环胞菌素,环孢菌素,环胞霉素A,环孢素A,环蒽孢A,环孢素)是一种由11个氨基酸组成的环状非核糖体肽,同时也是一种大环类化合物,可与亲环蛋白18(Cyp18)结合,抑制钙调神经磷酸酶(CaN)的活性,IC50值为7 nM。此外,Cyclosporin A还能抑制T细胞活化,具有免疫抑制活性,可用于干眼症、类风湿性关节炎和银屑病的相关研究。 |
M20413 | 4-Biphenylacetic acid | 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors. |
M25413 | Fucoxanthin | 岩藻黄质 Fucoxanthin 是一种天然存在于某些藻类中的类胡萝卜素,具有抗肥胖、抗氧化、抗糖尿病、抗癌和抗炎活性。 |
M31316 | DiaPep277 | DiaPep277 是一种基于热休克蛋白60(HSP60)437至460残基的,包含24个氨基酸的肽,可用于1型糖尿病免疫系统的相关研究。 |
M29608 | MRS4620 | MRS4620 是一种有效的 CD73 抑制剂,Ki 值为 0.436 nM。MRS4620 可用于癌症免疫研究的研究。 |
M21029 | MRE-269(ACT-333679) | MRE-269(ACT-333679) is a prostaglandin I2 (IP) receptor agonist with a binding affinity for the human IP receptor that is 130-fold greater than that for other human prostanoid receptor. |
M21012 | Loxoprofen Sodium | Loxoprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group |
M20970 | Adelmidrol | Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities. |
M20960 | Tinoridine hydrochloride | Tinoridine hydrochloride is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity. |
M20939 | Diclofenac Epolamine | Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. |
M20675 | Etofenamate | Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain. |
M20667 | Anisodamine Hydrobromide | Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs). |
M20567 | Salicylamide | Salicylamide is a non-prescription drug with analgesic and antipyretic properties. |
M20561 | Picolinic acid (PCL 016) | PCL016 is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function. |
M20544 | Trans-Tranilast | Trans-Tranilast可用于支气管哮喘,过敏性鼻炎和特应性皮炎的相关研究。 |
M20536 | Setipiprant (ACT-129968, KYTH-105) | Setipiprant(ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1. |
M20448 | Actarit | Actarit is an orally active immunomodulator used in the treatment of rheumatoid arthritis. |
M20418 | Dehydroandrographolide Succinate Potasium Salt | Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. |
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