M4614
|
Orientin |
Orientin（荭草苷）是一种可从药用植物中分离的生物活性化合物，能有效地抑制Sortase A的活性，其IC50为50.44 ± 0.51 µM。还可以通过Nrf2以及JNK/cytochrome c/caspase-3信号通路，抑制APAP诱导的肝细胞氧化损伤和线粒体功能障碍，具有抗氧化，抗炎和抗癌活性。 |
| M9358
|
ITE |
ITE是一种有效的，内源性的芳烃受体（AhR）的激动剂，可直接与AhR结合，Ki为3 nM。 |
| M10093
|
α-Galactosyl Ceramide |
α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) α-半乳糖神经酰胺 是一种强大的NKT细胞刺激剂，和选择性CD1d配体。α-Galactosylceramide (α-GalCer) 是一种合成的糖脂，具有抗肿瘤和免疫刺激作用。 |
| M1831
|
Cyclosporine A |
Cyclosporine A （环胞霉素A; 环孢菌素 A; CsA; Cyclosporin A）是一种免疫抑制剂和钙调素磷酸酶抑制剂，Cyclosporine A能够抑制T淋巴细胞的增殖和分化，以及抑制IL-2、IFN-γ等细胞因子的分泌，目前主要用于狼疮肾炎、风湿性关节炎、银屑病等炎症性和自身免疫性疾病的研究，以及器官移植研究。 |
| M20413
|
4-Biphenylacetic acid |
4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors. |
| M25413
|
Fucoxanthin |
岩藻黄质 Fucoxanthin 是一种天然存在于某些藻类中的类胡萝卜素，具有抗肥胖、抗氧化、抗糖尿病、抗癌和抗炎活性。 |
| M55368
|
2-Hydroxy Fluorene |
2-Hydroxy Fluorene (2-FLU) 在生命科学相关研究中具有广泛的应用。2-FLU 可以增加 HaCaT 细胞中牛皮癣相关炎症因子的表达。 |
| M55040
|
Litifilimab |
Litifilimab 是一种靶向 C 型凝集素域家族 4 成员 C（CLEC4C）的人源化 IgG1-κ 抗体。 |
| M31365
|
Efgartigimod |
Efgartigimod（ARGX-113，艾加莫德）是一种人IgG1抗体Fc衍生片段，同时也是Fc受体拮抗剂，可用于重症肌无力（MG），原发性免疫性血小板减少症（ITP）等自身免疫性疾病的相关研究。 |
| M31316
|
DiaPep277 |
DiaPep277 是一种基于热休克蛋白60（HSP60）437至460残基的，包含24个氨基酸的肽，可用于1型糖尿病免疫系统的相关研究。 |
| M29608
|
MRS4620 |
MRS4620 是一种有效的 CD73 抑制剂，Ki 值为 0.436 nM。MRS4620 可用于癌症免疫研究的研究。 |
| M21012
|
Loxoprofen Sodium |
Loxoprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group |
| M20970
|
Adelmidrol |
Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities. |
| M20960
|
Tinoridine hydrochloride |
Tinoridine hydrochloride is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity. |
| M20939
|
Diclofenac Epolamine |
Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. |
| M20675
|
Etofenamate |
Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain. |
| M20667
|
Anisodamine Hydrobromide |
Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs). |
| M20567
|
Salicylamide |
Salicylamide is a non-prescription drug with analgesic and antipyretic properties. |
| M20544
|
Trans-Tranilast |
Trans-Tranilast可用于支气管哮喘，过敏性鼻炎和特应性皮炎的相关研究。 |
| M20536
|
Setipiprant (ACT-129968, KYTH-105) |
Setipiprant(ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1. |
| M20448
|
Actarit |
Actarit is an orally active immunomodulator used in the treatment of rheumatoid arthritis. |
| M20418
|
Dehydroandrographolide Succinate Potasium Salt |
Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. |
| M18777
|
Protostemonine |
Protostemonine 原百部碱 是一种主要从 Stemona sesslifolia 根中分离得到的生物碱，对哮喘及革兰氏阴性菌所致急性肺损伤有抗炎作用。 |
