M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7423
|
TRAM 39 |
TRAM 39 is a potent K
Ca3.1 blocker. |
| M7422
|
Tracazolate hydrochloride |
Tracazolate hydrochloride is a subtype-selective GABA
A allosteric modulator. |
| M7420
|
TP 003 |
TP 003 is a functionally selective GABA
A receptor (α3 subtype) partial agonist. |
| M7418
|
Tocrifluor T1117 |
Tocrifluor T1117 is a fluorescent cannabinoid ligand; fluorescent form of AM 251. |
| M7417
|
TNP |
TNP is a inhibitor of IP6K; also inhibits IP3K. |
| M7415
|
TMPH hydrochloride |
TMPH hydrochloride is a neuronal nicotinic receptor antagonist. |
| M7411
|
threo Ifenprodil hemitartrate |
threo Ifenprodil hemitartrate is a nR2B-selective NMDA antagonist; also σ agonist. |
| M7406
|
TFM-4AS-1 |
TFM-4AS-1 is a selective androgen receptor modulator (SARM). |
| M7405
|
TFC 007 |
TFC 007 is a potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. |
| M7403
|
Tetrindole mesylate |
Tetrindole mesylate is a mAO-A inhibitor. |
| M7401
|
Telenzepine dihydrochloride |
Telenzepine dihydrochloride is a potent, selective M
1 antagonist. |
| M7400
|
Teijin compound 1 |
Teijin compound 1 is a potent CCR2b antagonist. |
| M7399
|
TC-T 6000 |
TC-T 6000 is a potent equilibrative nucleoside transporter 4 (ENT4) inhibitor. |
| M7397
|
TCS PrP Inhibitor 13 |
TCS PrP Inhibitor 13 is a antiprion agent; inhibits PrP
Sc accumulation. |
| M7394
|
TCS HDAC6 20b |
TCS HDAC6 20b is a selective HDAC6 inhibitor. |
| M7393
|
TC-S 7010 |
TC-S 7010 is a potent and selective Aurora kinase A inhibitor. |
| M7392
|
TC-S 7009 |
TC-S 7009 is a high affinity and selective HIF-2α inhibitor. |
| M7390
|
TC-S 7004 |
TC-S 7004 is a potent and selective DYRK1A/B inhibitor. |
| M7389
|
TC-S 7003 |
TC-S 7003 is a potent Lck inhibitor. |
| M7386
|
TCS 46b |
TCS 46b is a orally active, subtype-selective NR1A/NR2B antagonist. |
