M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7496
|
XRP44X |
XRP44X is a ras-Net pathway inhibitor. |
| M7494
|
XE 991 dihydrochloride |
XE 991 dihydrochloride is a potent, selective K
V7 (KCNQ) channel blocker; blocks M-currents. |
| M7492
|
XAP 044 |
XAP 044 is a potent and selective mGlu
7 antagonist. |
| M7491
|
WR 1065 |
WR 1065 is a p53 activator. Also ROS scavenger. |
| M7488
|
WIN 64338 hydrochloride |
WIN 64338 hydrochloride is a bradykinin B
2 antagonist. |
| M7485
|
WAY 208466 dihydrochloride |
WAY 208466 dihydrochloride is a selective 5-HT
6 agonist. |
| M7484
|
WAY 207024 dihydrochloride |
WAY 207024 dihydrochloride is a gnRH receptor antagonist. |
| M7482
|
WAY 181187 oxalate |
WAY 181187 oxalate is a high affinity and selective 5-HT
6 agonist. |
| M7480
|
W-5 hydrochloride |
W-5 hydrochloride is a calmodulin antagonist. |
| M7479
|
VUF 8430 dihydrobromide |
VUF 8430 dihydrobromide is a potent, high affinity H
4 agonist. |
| M7478
|
VUF 5574 |
VUF 5574 is a potent, selective hA
3 antagonist. |
| M7477
|
VU 1545 |
VU 1545 is a mGlu
5 positive allosteric modulator. |
| M7476
|
VU 0483605 |
VU 0483605 is a positive allosteric modulator at mGlu
1. |
| M7475
|
VU 0469650 hydrochloride |
VU 0469650 hydrochloride is a potent and selective negative allosteric modulator of mGlu
1. |
| M7474
|
VU 0422288 |
VU 0422288 is a selective group III mGlu positive allosteric modulator. |
| M7473
|
VU 0409106 |
VU 0409106 is a potent and selective negative allosteric modulator at mGlu
5. |
| M7471
|
VU 0364739 hydrochloride |
VU 0364739 hydrochloride is a potent and selective PLD2 inhibitor. |
| M7470
|
VU 0360223 |
VU 0360223 is a negative allosteric modulator at mGlu
5. |
| M7469
|
VU 0240551 |
VU 0240551 is a kCC2 inhibitor. |
| M7468
|
VU 0155041 sodium salt |
VU 0155041 sodium salt is a potent, positive allosteric mGlu 4 agonist. |
