M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7609
|
AN-9 |
HDAC Inhibitor tested as an anti-cancer drug; butyric acid pro-drug. |
| M7608
|
AH23848 hemicalcium salt |
EP4 prostanoid receptor antagonist with TP blocking activity. |
| M7605
|
Aprindine hydrochloride |
Aprindine hydrochloride is a class Ib antiarrhythmic and hERG channel blocker. |
| M7604
|
5-AIQ hydrochloride |
5-AIQ盐酸盐是聚(adp -核糖)聚合酶-1 (PARP-1)的抑制剂。 |
| M7602
|
Acepromazine maleate |
Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). |
| M7601
|
Aminoguanidine hemisulfate salt |
Inhibits both constitutive and inducible nitric oxide synthetase. |
| M7600
|
AS-136A |
AS-136A是一种有效的麻疹病毒RdRp抑制剂。 |
| M7599
|
ABT-418 hydrochloride |
Neuronal nicotinic acetylcholine receptor agonist with cognition enhancing and anxiolytic activities. |
| M7595
|
AL-8810 |
AL-8810是一种新型前列腺素F2α类似物;选择性FP前列腺素受体拮抗剂。 |
| M7594
|
AH 11110 |
α1B-adrenoceptor ligand. |
| M7593
|
ATPA |
Selective kainate receptor agonist. |
| M7592
|
5α-Androstan-3β-ol |
mCAR (constitutive androstane receptor) inverse agonist; testosterone metabolite. |
| M7589
|
Arecaidine propargyl ester hydrobromide |
Potent muscarinic acetylcholine receptor agonist exhibiting slight selectivity for M2 receptors; inactive at nicotinic receptors. |
| M7586
|
AC-7954 |
Nonpeptide GPR14 / urotensin-UII (UII) receptor agonist that has an EC50 of 300 nM at the human UII receptor (h-UTR). |
| M7503
|
YM 511 |
YM 511 is a potent aromatase (CYP19) inhibitor. |
| M7502
|
YM 298198 hydrochloride |
YM 298198 hydrochloride is a highly potent, selective non-competitive mGlu
1 antagonist. |
| M7501
|
YM 022 |
YM 022 is a highly potent, selective non-peptide CCK
2 antagonist. |
| M7499
|
YE 120 |
YE 120 is a gPR35 agonist. |
| M7498
|
Y-26763 |
Y-26763 is a k
ir6 (K
ATP) channel opener. |
| M7497
|
Y 11 |
Y 11 is a potent and selective FAK inhibitor. |
