找到约 30 条 “TAM Receptor” 相关结果 （用时 0.262 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M25486
|
(S)-(+)-Dimethindene maleate | (S)-(+)-Dimethindene maleate | AChR/AChE |
| (S)-(+)-Dimethindene maleate 是一种有效的选择性毒蕈碱 M2 受体拮抗剂 (pA2 = 7.86/7.74; pKi = 7.78)。(S)-(+)-Dimethindene maleate 也是一种组胺 H1 受体 (histamine H1 receptor) 拮抗剂 (pA2 = 7.48)。 | |||
| M2088
|
Ciproxifan maleate | Ciproxifan maleate | Histamine Receptor |
| FUB 359 maleate | |||
| Ciproxifan（CPX）是一种高效的，选择性的histamin H3-receptor拮抗剂，IC50为9.2 nM，作用于其他受体亚型具有低亲和力。 | |||
| M2180
|
SGI-7079 | SGI-7079 | TAM Receptor |
| SGI-7079 是一种 ATP-竞争性 Axl 抑制剂，Axl蛋白属于TAM（Tyro3-Axl-Mer）Receptor家族。SGI-7079显著抑制 SUM149 和 KPL-4 细胞增殖，IC50 分别为 0.43 和 0.16 μM。 | |||
| M2280
|
Tamoxifen Citrate (ICI 46474) | 枸橼酸他莫昔芬；柠檬酸三苯氧胺；柠檬酸它莫西芬；柠檬酸他莫昔芬 | Estrogen Receptor |
| ICI 46474; Istubal; Nolvadex | |||
| Tamoxifen Citrate是一种雌激素受体（Estrogen Receptor）拮抗剂，与雌激素竞争性结合。 | |||
| M2522
|
Ciproxifan | Ciproxifan | Histamine Receptor |
| FUB-359 | |||
| Ciproxifan（CPX）是一种高效的，选择性的histamin H3-receptor拮抗剂，IC50为9.2 nM，作用于其他受体亚型具有低亲和力。 | |||
| M2639
|
Dimaprit dihydrochloride | Dimaprit dihydrochloride | Histamine Receptor |
| Dimaprit is a histamine type 2 receptor agonist. | |||
| M2643
|
Diphenylpyraline hydrochloride | 盐酸二苯比拉林；双苯比拉林盐酸盐 | Histamine Receptor |
| 4-Diphenylmethoxy-1-methylpiperidine hydrochloride | |||
| Diphenylpyraline hydrochloride (DPP) is an internationally available antihistamine that produces therapeutic antiallergic effects by binding to histamine H₁ receptors. | |||
| M2671
|
Epinastine hydrochloride | 依匹斯汀盐酸盐 | Histamine Receptor |
| WAL801 hydrochloride | |||
| Epinastine HCl是一种抗组胺剂和肥大细胞稳定剂。Epinastine hydrochloride 是一种有效的，选择性的，具有口服活性的组胺 H1 受体 (histamine H1 receptor) 拮抗剂。 | |||
| M2784
|
JNJ-7777120 | JNJ-7777120 | Histamine Receptor |
| JNJ-7777120是第一个，有效的，选择性非咪唑histamine H4 receptor拮抗剂，Ki为4.5 nM，比作用于其他组胺受体选择性高1000倍以上。 | |||
| M3605
|
Salbutamol hemisulfate | 沙丁胺醇半硫酸盐；阿布叔醇 | Adrenergic Receptor |
| Albuterol hemisulfate; AH-3365 hemisulfate | |||
| Salbutamol hemisulfate 是一种短效的β2-肾上腺素能受体（β2 adrenergic receptor）激动剂，IC50为8.93 µM。能用于哮喘和慢性阻塞性肺疾病（COPD）相关研究。 | |||
| M5752
|
Loratadine | 氯雷他定 | Histamine Receptor |
| SCH29851 | |||
| Loratadine是一种选择性的histamine H1 receptor拮抗剂，用于治疗过敏。同时还是一种选择性的B(0)AT2抑制剂，其IC50为 4 μM。 | |||
| M5921
|
Ranitidine hydrochloride | 盐酸雷尼替丁 | Histamine Receptor |
| AH19065 Hydrochloride | |||
| Ranitidine hydrochloride 是一种有效的，选择性的，具有口服活性的组胺 H2 受体 (histamine H2-receptor) 拮抗剂，IC50 为 3.3 μM。 | |||
M7353
|
Tamoxifen | 他莫昔芬 | Estrogen Receptor |
| ICI47699; Z-Tamoxifen; trans-Tamoxifen | |||
| Tamoxifen是一种选择性雌激素受体调节剂 (Selective estrogen receptor modulators，SERM)，可阻断乳腺细胞中的雌激素作用。Tamoxifen 也是一种有效的 Hsp90 激活剂，可增强 Hsp90 分子伴侣 ATPase 的活性。Tamoxifen 还可以有效抑制传染性 EBOV Zaire 和 Marburg (MARV)，IC50 分别为 0.1 µM 和 1.8 µM。 | |||
| M7654 | Biphenyl-indanone A | Biphenyl-indanone A | Others |
| Biphenyl-indanone A (BINA) is a potent selective positive allosteric modulator for the group II metabotropic glutamate receptor subtype mGluR2. | |||
| M7689 | Caroverine hydrochloride | Caroverine hydrochloride | Others |
| Caroverine hydrochloride is a nonselective NMDA and AMPA glutamate receptor antagonist. | |||
| M7722 | Ciproxifan hydrochloride | 环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯基]甲酮盐酸盐 | Others |
| Ciproxifan（CPX） belongs to a novel chemical series of histamine H3-receptor antagonists. | |||
| M7741
|
DNQX | 二硝基喹酮 | Others |
| FG 9041 | |||
| DNQX（二硝基喹酮，FG 9041）是一种喹恶啉衍生物，属于非NMDA (non-NMDA glutamate receptor) 谷氨酸受体拮抗剂，对AMPA和kainate受体的IC50值分别为0.5 µM和2 µM。 | |||
| M7745 | DCB | DCB | Others |
| Neutral allosteric modulator of the metabotropic glutamate receptor mGluR5. | |||
| M7766 | Domoic acid | 软骨藻酸 | Others |
| Potent agonist at receptors for excitatory amino acids glutamate and kainate; has highest affinity for AMPA/kainate receptor of any kainate agonist; causes excessive excitation of neurons leading to depletion of energy stores. | |||
| M7849 | Imetit dihydrobromide | Imetit dihydrobromide | Others |
| Potent and selective H3 histamine receptor agonist. | |||
| M7856 | Immepip dihydrobromide | Immepip dihydrobromide | Others |
| Immepip is a H3 and H4 histamine receptor agonist. | |||
| M7881 | LY-487379 hydrochloride | LY-487379 hydrochloride | Others |
| LY-487379 is a positive allosteric modulator of the metabotropic glutamate receptor mGluR2. | |||
| M7888 | Levocabastine hydrochloride | 左旋多巴 | Others |
| Non-peptide histamine H1 receptor antagonist; neurotensin NTS2 receptor ligand. | |||
| M7907 | MPPG | MPPG | Others |
| Group III/II metabotropic glutamate (mGluR) receptor antagonist. | |||
| M7920 | MMPIP | MMPIP | Others |
| MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). | |||
| M8139 | Ridaifen-B | Ridaifen-B | Others |
| Ridaifen-B (RID-B) is a novel tamoxifen (TAM) analog that significantly augments apoptosis-inducing effect of TAM in estrogen receptor (ER)-negatives cells. | |||
| M8229 | Conessine | 地麻素；康丝碱；可内新；抗痢夹竹桃碱；锥丝碱；止泻木碱 | Others |
| Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors (Ki = 5. | |||
| M8256 | EAA-090 | EAA-090 | Others |
| EAA-090 inhibits the binding of ligands to glutamate receptors and blocks NMDA-induced currents. | |||
| M8264
|
CDPPB | CDPPB | Others |
| Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. | |||
| M8469 | Ro 67-4853 | Ro 67-4853 | Others |
| Ro67-4853 is a positive allosteric modulator of metabotropic glutamate 1 (mGlu1) receptors. | |||
