TAI-1 - 搜索结果 | AbMole中文官网

找到约 19 条 “TAI-1” 相关结果（用时 0.109 秒）

目录号	产品名称	中文名称	靶点
M5293	Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO)	蛋白酶抑制剂Cocktail（不含EDTA，100X DMSO储液）	Inhibitor Cocktails
	AbMole蛋白酶抑制剂Cocktail（不含EDTA，100X DMSO储液）是一种低毒，全面的蛋白保护试剂，最大限度地保护蛋白免受蛋白酶降解威胁，提高蛋白得率。
M13406	Deacetylase Inhibitor Cocktail (100X)	去乙酰化酶抑制剂Cocktail（100X）	Inhibitor Cocktails
	AbMole去乙酰化酶抑制剂Cocktail（100X）是一种用于维持组蛋白和其它非组蛋白乙酰化状态的去乙酰化酶抑制剂混合物。AbMole去乙酰化酶抑制剂Cocktail（100X）以 1 mL 小管的形式提供。每个小管含有 1 mL 70% DMSO及以下成分：Trichostatin A (40 μM)，EX-527 (1 mM)，Nicotinamide (400 mM) 和 Sodium Butyrate (200 mM)。
M20601	TAI-1	TAI-1	Microtubule
	TAI-1 是一种首创的（first-in-class），强效的，特异性的，具有口服活性的 Hec1 抑制剂，能破坏 Hec1-Nek2 蛋白的相互作用。
M2830	Mdivi-1	Mdivi-1	Dynamin
	Mitochondrial division inhibitor 1
	Mdivi-1（Mitochondrial division inhibitor 1）是一种动力蛋白相关蛋白1 (Drp1)的GTP酶抑制剂，可调节线粒体动力蛋白的表达，IC50为10 μM。同时能抑制NF-κB信号通路和NLRP3炎症小体的激活。此外，mdivi-1还可通过浓度依赖性的方式，降低快速激活延迟整流K⁺电流(I(Kr))的尾电流(I(tail))的振幅，其IC₅₀值为11.6 μM。Mdivi-1 是一种有效的线粒体分裂/线粒体自噬 (mitophagy) 抑制剂。
M8467	OF-1	OF-1	Others
	OF-1 is a chemical probe for the bromodomains of the BRPF (BRomodomain and PHD Finger containing) family of scaffolding proteins (BRPF1, BRPF2, BRPF3) that assemble histone acetyltransferase (HAT) complexes of the MYST family members MOZ and MORF.
M18083	Matairesinol 4'-O-β-gentiobioside	罗汉松树脂酚-4'-O-β-龙胆二糖苷	Others
	Matairesinol 4′-O-β-D-glucopyranoside 对 HeLa 细胞具有细胞毒活性，IC50 为 47.1 μM。
M18217	Matairesinol monoglucoside	Matairesinol monoglucoside	Others
	Matairesinol monoglucoside 是一种木脂素化合物，对 IFN-γ/STAT1 和 IL-6/STAT3 信号通路具有较低的抑制活性，抑制率分别为 5.8% 和 7.0%。
M25383	Recombinant Human KEAP1 Protein (Baculovirus-Insect)	重组人KEAP1蛋白 (Baculovirus-Insect)	Recombinant Proteins
	Kelch-like ECH-associated protein 1; INRF2
	Kelch-like ECH-associated protein 1 (KEAP1) is a cytoplasm and nucleus protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain, and six Kelch repeats. KEAP1 is a key regulator of the NRF2 transcription factor, which transactivates the antioxidant response element (ARE) and upregulates numerous proteins involved in antioxidant defense.
M25384	Recombinant Human KEAP1 Protein (Baculovirus-Insect, His & GST Tag)	重组人KEAP1蛋白 (Baculovirus-Insect, His & GST Tag)	Recombinant Proteins
	Kelch-like ECH-associated protein 1; INRF2
	Kelch-like ECH-associated protein 1 (KEAP1) is a cytoplasm and nucleus protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain, and six Kelch repeats. KEAP1 is a key regulator of the NRF2 transcription factor, which transactivates the antioxidant response element (ARE) and upregulates numerous proteins involved in antioxidant defense.
M25536	Recombinant Human CXCL13/BCA-1 (E. coli)	重组人CXCL13/BCA-1蛋白 (E. coli)	Recombinant Proteins
	CXC chemokine BLC; Small-inducible cytokine B13
	CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml.
M29887	BPDBA	BPDBA	GABA Receptor
	BPDBA 是一种选择性和非竞争性 betaine/GABA 转运体 (BGT-1) 抑制剂，对人 BGT-1 和小鼠 GAT2 的 IC50 分别为 20 μM 和 35 μM。
M30975	TLX agonist 1	TLX agonist 1	Others
	TLX agonist 1 (ccrp2) 是一种孤核受体 tailless (TLX, NR2E1) 调节剂 (EC50=1 μM; Kd= 650 nM)。TLX agonist 1 增强 TLX 转录抑制活性。
M31137	Recombinant Mouse R-spondin 1/RSPO1 Protein (CHO, C-His)	重组小鼠R-spondin 1/RSPO1蛋白 (CHO, C-His)	Recombinant Proteins
	R-Spondin-1 (Rspo-1) is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. In mice, RSPO1 induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
M40232	Demethylcarolignan E	Demethylcarolignan E	Others
	Demethylcarolignan E 是一种苯丙素酯，可以从木槿花 (Hibiscus taiwanensi) 的茎中分离出来。Demethylcarolignan E 对人类癌细胞系 A549 和 MCF-7 具有细胞毒性 (IC50: <10 μg/mL)。
M42177	SCS	SCS	GABA Receptor
	SCS (Salicylidene salicylhydraide) 是一种有效的、变构的、选择性的 β1-containing GABAA receptors 的抑制剂，通过 VIPR 测量，对 α2β1γ1θ 的 IC50 为 32 nM。
M43969	Recombinant Mouse MMP-12 (Mammalian, C-6His)	重组小鼠MMP-12 (Mammalian, C-6His)	Recombinant Proteins
	Matrix metalloproteinase-12
	Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity.
M43971	Recombinant Human MMP12 Protein (E. coli)	重组人MMP12 蛋白 (E. coli)	Recombinant Proteins
	Matrix metalloproteinase-12
	Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect.
M54749	Recombinant Rat IL-23 Protein (HEK293, C-His)	重组大鼠IL-23 蛋白 (HEK293, C-His)	Recombinant Proteins
	Interleukin-23; IL-23A; IL-23 alpha & IL-12 beta
	IL-23 (IL-23 alpha & IL-12 beta Heterodimer) Protein is a recombinant protein dimer complex containing rat-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293.
M54826	LUF5519	LUF5519	Adenosine Receptor
	LUF-5519
	LUF5519 is a ribose-containing adenosine A1 receptor agonist.

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