M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M6721
|
ETP 45658 |
ETP 45658 is a potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR. |
| M6719
|
Eticlopride hydrochloride |
Eticlopride hydrochloride is a selective D
2/D
3 antagonist. |
| M6716
|
ER 819762 |
ER 819762 is a potent EP
4 receptor antagonist; orally bioavailable. |
| M6715
|
ER 27319 maleate |
ER 27319 maleate is a selective Syk kinase inhibitor. |
| M6713
|
Eplivanserin hemifumarate |
Eplivanserin hemifumarate is a potent and selective 5-HT
2A antagonist. |
| M6712
|
EO 1428 |
EO 1428 is a selective inhibitor of p38α and p38β
2. |
| M6711
|
Enoximone |
Enoximone is a pDE3 inhibitor. |
| M6709
|
EMD 66684 |
EMD 66684 is a potent, selective non-peptide AT
1 antagonist. |
| M6708
|
EMD 386088 hydrochloride |
EMD 386088 hydrochloride is a potent 5-HT
6 agonist. |
| M6707
|
EMD 281014 hydrochloride |
EMD 281014 hydrochloride is a selective 5-HT
2A antagonist. |
| M6702
|
EGLU |
EGLU is a highly selective group II mGlu antagonist. |
| M6701
|
Eggmanone |
Eggmanone is a potent and selective PDE4 inhibitor; suppresses hedgehog signaling. |
| M6698
|
Edelfosine |
Edelfosine is a selective PI-PLC inhibitor, also PAF receptor agonist. |
| M6697
|
EC 144 |
EC 144 is a high affinity, potent and selective Hsp90 inhibitor. |
| M6696
|
EB 47 |
EB 47 is a potent PARP-1 inhibitor. |
| M6694
|
E4CPG |
E4CPG is a group I/group II mGlu antagonist. |
| M6689
|
DPCPX |
DPCPX is a a
1 selective antagonist. |
| M6684
|
DMP 543 |
DMP 543 is a potent, orally active ACh release enhancer. |
| M6683
|
DMH4 |
DMH4 is a selective VEGFR-2 inhibitor. |
| M6682
|
DMeOB |
DMeOB is a negative allosteric modulator at mGlu
5. |
