M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7791
|
Exo-1 |
Exo1是一种可逆的细胞外渗（exocytosis）抑制剂，也是高尔基ARF 1（ADP-Ribosylation Factor）GTP酶的激活剂。Exo1抑制细胞外渗，其IC50约为20μM。 |
M65723
|
Polypropylene glycol (MW 2000) |
Polypropylene glycol 2000 (PPG 2000) 是一种生化试剂，可用作生命科学相关研究的生物材料或有机化合物。 |
| M65713
|
DSPE-PEG-Galactose |
DSPE-PEG-Galactose 是一种靶向性纳米材料，由磷脂(DSPE)、聚乙二醇(PEG)和半乳糖组成，可在脂质体、纳米颗粒或膜蛋白体系中发挥靶向作用，通过半乳糖与肝细胞表面ASGPR受体的特异性结合实现精准靶向递送。 |
| M59439
|
Glyco-diosgenin |
Glyco-diosgenin 是一种合成的表面活性剂和去污剂，用于从膜中提取蛋白质以进行结构和功能研究，以及对膜蛋白质进行单粒子冷冻电子显微镜 (cryoEM) 研究。 |
| M59438
|
Decyl maltose neopentyl glycol |
Decyl maltose neopentyl glycol (DMNG) 是一种新戊二醇洗涤剂。Decyl maltose neopentyl glycol (DMNG,癸基麦芽糖新戊二醇) 具有低临界胶束浓度（CMC）和高溶解性，主要用于膜蛋白的溶解和稳定，能够模拟脂质双层环境而不破坏蛋白的寡聚态和天然构象。 |
| M59389
|
Liver Lysosomes, Mixed Gender |
肝溶酶体产品可用于体外进行 ADC 类药物连接子切割及小核酸类药物溶酶体逃逸试验验证。 |
| M59387
|
Orotidine |
Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants. |
| M59386
|
2'-F-Bz-A |
2'-F-Bz-A (N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides. |
| M59385
|
Tiazofurin |
Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. |
| M59384
|
Orotidine 5′-monophosphate trisodium |
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms. |
| M59382
|
Tadnersen |
Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion. |
| M59381
|
Trabedersen sodium |
Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). |
| M59380
|
ODN 1668 |
ODN 1668, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. |
| M59379
|
ODN 20844 |
ODN 20844, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. |
| M59378
|
CpG ODN 10101 |
CpG ODN 10101, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2(VQLRIRVAVIRA-NH2). |
| M59377
|
Zorevunersen |
Zorevunersen can be used for the research of Dravet syndrome. |
| M59376
|
Zilganersen |
Zilganersen can be used for the research of Alexander’s disease. |
| M59375
|
Zifcasiran sodium |
Zifcasiran sodium can be used for the research of advanced renal cell carcinoma. |
| M59374
|
Zerlasiran |
Zerlasiran can be used for the research of Lp(a)-mediated cardiovascular disease. |
| M59373
|
Vupanorsen |
Vupanorsen can be used for the research of hyperlipidemia. |
| M59372
|
Ulefnersen |
Ulefnersen can be used for the research of amyotrophic lateral sclerosis. |
