ROS Kinase - 搜索结果

找到约 41 条 “ROS Kinase” 相关结果（用时 0.157 秒）

目录号	产品名称	中文名称	靶点
M8974	ALW-II-41-27	ALW-II-41-27	Ephrin Receptor
	Eph receptor tyrosine kinase inhibitor
	ALW-II-41-27是一种有效的EPH家族激酶抑制剂，作用于EPHA2，IC50值为11 nM。
M27653	Tyrosine kinase inhibitor	Tyrosine kinase inhibitor	c-Met
M27653	Tyrosine kinase inhibitor 是一种有效的酪氨酸激酶抑制剂。
M43260	Abl protein tyrosine kinase substrate	Abl protein tyrosine kinase substrate	Others
M43260	Abl protein tyrosine kinase substrate 是一种有生物活性的肽。
M43486	Tyrosine kinase-IN-6	Tyrosine kinase-IN-6	c-Met
M43486	Tyrosine kinase-IN-6 是一种有效且有前景的 RON 剪接变异体抑制剂，具有抗癌和抗肿瘤作用。
M50406	Tyrosine Kinase Peptide 1	Tyrosine Kinase Peptide 1	Src-bcr-Abl
M50406	Tyrosine Kinase Peptide 1 是用于c-Src 激酶实验的对照底物。
M53314	Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)	Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)	JAK
M53314	Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) 是小鼠JAK2 对应的475到491氨基酸序列的多肽。
M54265	EGFR Protein Tyrosine Kinase Substrate	EGFR Protein Tyrosine Kinase Substrate	EGFR/HER2
M54265	EGFR Protein Tyrosine Kinase Substrate 是EGFR 酪氨酸激酶的底物。
M55299	Recombinant Human FLT3L (HEK293, C-6His)	重组人FLT3L (HEK293, C-6His)	Cytokines and Growth Factors
	Fms-like Tyrosine Kinase 3 Ligand
	Fms-like Tyrosine Kinase 3 Ligand (FLT3L，FMS样胰激酶3配体) is a hematopoietic four helical bundle cytokine. Flt‑3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.
M55567	Recombinant Human ROR2 (HEK293, C-6His)	重组人ROR2 (HEK293, C-6His)	Cytokines and Growth Factors
	Receptor Tyrosine Kinaselike Orphan Receptor 2; NTRKR2
	Receptor Tyrosine Kinaselike Orphan Receptor 2(ROR2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. ROR2 promotes osteogenesis, binds YWHAB and Interacts with WTIP.
M57208	PDGFR Tyrosine Kinase Inhibitor III	PDGFR Tyrosine Kinase Inhibitor III	VEGFR/PDGFR
M57208	PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III)是一种多激酶抑制剂，可抑制 PDGFR、EGFR、FGFR、PKA 和 PKC 等。可用于研究肌萎缩侧索硬化症。
M58375	Recombinant Human HER2 Protein (HEK293, C-6His)	重组人HER2 蛋白 (HEK293, C-6His)	Cytokines and Growth Factors
	Receptor tyrosine-protein kinase erbB-2; ERBB2; MLN19; NGL; TKR1
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation.
M2912	Pacritinib	帕克替尼；帕瑞提尼	JAK
	SB1518
	Pacritinib (SB1518)是一种大环类化合物，同时也是有效的Janus Kinase 2 (JAK2)和Fms-Like Tyrosine Kinase-3 (FLT3)的选择性抑制剂，IC50分别为23 nM和22 nM。
M4875	UNC2881	UNC2881	TAM Receptor
M4875	UNC2881 is a specific Mer tyrosine kinase inhibitor with IC50 of 4.3 nM, about 83- and 58-fold selectivity over Axl and Tyro3, respectively
M4937	Icotinib Hydrochloride	盐酸埃克替尼	EGFR/HER2
	BPI-2009H
	Icotinib Hcl(BPI-2009H) is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
M9257	Evobrutinib	埃沃布鲁替尼	BTK
	MSC-2364447C
	Evobrutinib是一种高选择性的共价的BTK（Bruton's Tyrosine Kinase）抑制剂，IC50为8.9 nM。Evobrutinib常用于多发性硬化症（MS）等自身免疫性疾病的研究。Evobrutinib通过共价结合BTK，抑制B细胞受体（BCR）信号通路的激活，从而调节B细胞的发育、增殖和存活。此外，它还可以抑制巨噬细胞活性以及抗体和细胞因子的产生与释放，对适应性和先天性免疫系统均有影响。
M6910	LM22A-4	LM22A-4	Trk
	LM22A4
	LM22A-4 是一种有效的，特异性的 tyrosine kinase receptor B (TrkB) 激动剂，常用于神经系统疾病研究。
M7753	DAPH	DAPH	Others
M7753	DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.
M7867	JNJ-10198409	JNJ-10198409	Others
M7867	JNJ-10198409 is a potent ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenicand a directtumor cell antiproliferative activity.
M7942	Necrostatin-5	Necrostatin-5	RIPK
M7942	Necrostatin-5 is an inhibitor of necroptosis (non-apoptotic cell death pathway) by indirect inhibition of RIP1 kinase.
M8043	PD-161570	PD-161570	Others
M8043	PD-161570 is an inhibitor of human FGF-1 receptor tyrosine kinase.
M8059	PD-180970	PD-180970	Others
M8059	PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase.
M8061	SU5614	SU5614	Others
M8061	SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases.
M8152	ST638	ST638	Others
M8152	Protein tyrosine kinase inhibitor (IC₅₀ = 370 nM).
M8296	DMPQ dihydrochloride	DMPQ dihydrochloride	Others
M8296	DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC₅₀ = 80 nM.
M8440	PKI-166	PKI-166	Others
M8440	PKI-166 is a potent, selective and orally available EGF-R tyrosine kinase inhibitor.
M8813	Tyrphostin AG 825	Tyrphostin AG 825	Others
M8813	EGF receptor tyrosine kinase inhibitor, inactive against IGF-1 Receptor.
M8820	Tyrphostin RG 14620	Tyrphostin RG 14620	Others
	Tyrphostin RG14620
	Non-phenolic tyrphostin-class tyrosine kinase inhibitor.
M8827	Tyrphostin 51	Tyrphostin 51	Others
M8827	Tyrphostin 51 is an EGFR tyrosine kinase inhibitor.
M9465	MAZ51	MAZ51	VEGFR/PDGFR
	MAZ-51
	MAZ51 is originally synthesized inhibitor of VEGFR-3 (Flt-4) tyrosine kinase, inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2.
M10095	Orelabrutinib	奥布替尼	BTK
	ICP-022
	Orelabrutinib (ICP-022)是一种有效的、口服活性的且不可逆的 Bruton's tyrosine kinase (BTK) 的抑制剂。可用于多发性硬化症（MS）的相关研究。
M10386	MT-802	MT-802	PROTAC
M10386	MT-802 是一种基于PROTAC技术的BTK降解剂，可诱导 Bruton's tyrosine kinase (BTK) 的降解。MT-802 可将BTK募集到 cereblon E3 ubiquitin ligase complex 中，以通过蛋白酶体触发BTK泛素化和降解。
M10497	ONO-7475	ONO-7475	TAM Receptor
	ONO7475
	ONO-7475 是一种有效的，选择性的，具有口服活性的 Anexelekto (Axl) / MER tyrosine kinase 抑制剂，IC50值分别为0.7 nM和1.0 nM。
M10559	Tyrphostin A1	Tyrphostin A1	IL Receptor/Related
	Tyrphostin 1
	Tyrphostin A1 is a weaker EGFR tyrosine kinase inhibitor, Tyrphostin A1 inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.
M14922	TG 100801	TG 100801	VEGFR/PDGFR
M14922	TG 100801 是TG 100572的前药，通过去酯化产生TG 100572，开可用于黄斑变性的研究。TG 100572 是多靶点激酶抑制剂，抑制受体酪氨酸激酶 (receptor tyrosine kinases) 和Src激酶 (Src kinases); 对VEGFR1，VEGFR2，FGFR1，FGFR2，PDGFRβ，Fgr，Fyn，Hck，Lck，Lyn，Src，Yes 的 IC50 值分别为2，7，2，16，13，5，0.5，6，0.1，0.4，1，0.2。
M15073	Recombinant Human HGF (HEK293, C-6His)	重组人HGF蛋白 (HEK293, C-6His)	Cytokines and Growth Factors
	Hepatocyte growth factor; HPTA; Scatter factor
	HGF is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis.
M15076	Recombinant Mouse HGF (HEK293,C-6His)	重组小鼠HGF蛋白 (HEK293,C-6His)	Cytokines and Growth Factors
	Hepatopoietin-A;Scatter factor;SF;deafness, autosomal recessive 39
	Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis.
M20022	GI-560708	GI-560708	Src-bcr-Abl
M20022	GI-560708 is a inhibitor of BCR-ABL tyrosine kinase.
M20053	WAY-277054	WAY-277054	Others
M20053	WAY-277054 is a tyrosine kinase inhibitor
M20094	WAY-321366	WAY-321366	Others
M20094	WAY-321366 is a abelson tyrosine kinase inhibitor
M20120	WAY-327480	WAY-327480	ROS
M20120	WAY-327480 has inhibition of ROS tyrosine kinase.
M20129	WAY-329592	WAY-329592	Others
M20129	WAY-329592 has Tyrosine kinase inhibitory activity.

AbMole

服务支持

技术资源