找到约 30 条 “GABA Receptor” 相关结果 （用时 0.164 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M28615 | GABAA receptor agent 1 | GABAA receptor agent 1 | GABA Receptor |
| GABAA receptor agent 1 是 GABAA 受体的高亲和力配体，具有较强的抗惊厥活性。 | |||
M4959
|
Pagoclone | 帕戈隆 | GABA Receptor |
| (+)-RP-59037; IP-456; RP-62955; CI-1043 | |||
| Pagoclone是有活性的(+)-RP59037，为GABA(A) receptor的局部激活剂，可用于恐慌和焦虑等精神类疾病的相关研究。 | |||
| M6828 | Indiplon | 茚地普隆 | Others |
| Indiplon is a subtype-selective GABA A receptor positive allosteric modulator. | |||
| M6915 | Loreclezole hydrochloride | 氯瑞唑 | Others |
| Loreclezole hydrochloride is a subtype-selective GABA A receptor modulator. | |||
| M7087 | Org 20599 | Org 20599 | Others |
| Org 20599 is a positive allosteric modulator and direct agonist of GABA A receptors. | |||
| M7158 | Pregnanolone | 孕烷醇酮 | Others |
| Pregnanolone is a gABA A receptor positive allosteric modulator. | |||
| M7381
|
TCS 1105 | TCS 1105 | Others |
| TCS 1105 is a gABA A α2 benzodiazepine receptor agonist. | |||
| M7382 | TCS 1205 | TCS 1205 | Others |
| TCS 1205 is a subtype-selective GABA A receptor agonist. | |||
| M7410
|
THIP hydrochloride | 加波沙朵盐酸盐 | GABA Receptor |
| Gaboxadol hydrochloride; Lu 02-030 HCl | |||
| THIP hydrochloride (Gaboxadol hydrochloride) 是一种 GABAA receptor 激动剂和 GABAC receptor 拮抗剂，可以作为一种非阿片类的动物实验麻醉剂或镇痛剂。THIP还可用于亨廷顿病、睡眠、厌食等多方面的研究。 | |||
| M7420 | TP 003 | TP 003 | Others |
| TP 003 is a functionally selective GABA A receptor (α3 subtype) partial agonist. | |||
| M7441 | U 90042 | U 90042 | Others |
| U 90042 is a gABA A receptor ligand. | |||
| M7442
|
U 93631 | U 93631 | GABA Receptor |
| U 93631 is a gABA A receptor antagonist. | |||
| M7697 | Chlorprothixene hydrochloride | 盐酸氯普噻吨 | Others |
| D2 dopamine receptor antagonist; blocks a subset of GABAA receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic. | |||
| M7740 | DS1 | DS1 | Others |
| δ-GABAA receptors are emerging as an important pharmacological target. | |||
| M7762 | DS2 | DS2 | Others |
| DS2 is a selective positive allosteric modulator of δ-GABAA receptors. | |||
| M7899 | L-655,708 | L-655,708 | Others |
| Novel ligand selective for the benzodiazepine site of GABAA receptors which contain the α5 subunit. | |||
| M8151
|
SR-95531 | SR-95531 | Others |
| SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities. | |||
| M8314 | CGS 9895 | CGS 9895 | Others |
| CGS 9895 is a GABA antagonist that acts via the benzodiazepine binding site of ag containing GABA receptors. | |||
| M8547 | Thiocolchicoside | 硫秋水仙苷；噻可撒可 | Others |
| Thiocolchicoside is a potent competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist with muscle relaxant, anti-inflammatory, and analgesic activity. | |||
| M8564 | GS39783 | GS39783 | Others |
| GS39783 is a positive allosteric modulator (PAM) of GABA-B receptors. | |||
| M8579 | CMPPE | CMPPE | Others |
| CMPPE is a GABAB receptor positive allosteric modulator (PAM). | |||
| M8828 | Tofisopam | 托非索洋 | Others |
| Ligand for the GABAA receptor benzodiazepine modulatory site. | |||
| M27944
|
Broflanilide | 氟苯双酰胺 | GABA Receptor |
| Broflanilide 是一种杀虫剂，可以分解成 Desmethyl-Broflanilide，为特异性的昆虫耐狄氏剂的 GABA Receptor 拮抗剂，抑制斜纹夜蛾 RDL GABAR，IC50 值为 1.3 nM。 | |||
| M29148 | RWJ-51204 | RWJ-51204 | GABA Receptor |
| RWJ-51204 是 GABA(A) receptor 的部分激动剂，Ki 值为 0.2-2 nM。 | |||
| M30031 | Bicuculline methochloride | Bicuculline methochloride | GABA Receptor |
| (+)-Bicuculline methochloride; d-Bicuculline methochloride | |||
| Bicuculline ((+)-Bicuculline; d-Bicuculline) 甲基氯化物是一种惊厥生物碱，是选择性 GABAA 受体 (GABAA receptor) 的拮抗剂，IC50 为 3 μM。Bicuculline 甲基氯化物在哺乳动物中可以诱导阵挛性强直性惊厥，还可用于阻断 Ca2+ 激活的钾通道。Bicuculline 甲基氯化物可用于癫痫等相关精神疾病的研究。 | |||
| M30436 | Bicuculline methobromide | Bicuculline methobromide | GABA Receptor |
| (+)-Bicuculline methobromide; d-Bicuculline methobromide | |||
| Bicuculline methobromide 是一种选择性GABAA 受体 (GABAA Receptor) 拮抗剂，IC50 值为 3 μM。Bicuculline methobromide 在哺乳动物中可以诱导阵挛性强直性惊厥，还可用于阻断 Ca2+ 激活的钾通道。Bicuculline methobromide 可用于癫痫等相关精神疾病的研究。 | |||
| M30609
|
FG 7142 | FG 7142 | GABA Receptor |
| ZK 39106; LSU-65 | |||
| FG 7142 (ZK 39106; LSU-65) 是一种非选择性的苯二氮杂卓反向激动剂，对含 α1 亚基的 GABAA receptor 具有高亲和力 (Ki= 91 nM)。FG 7142 (ZK 39106; LSU-65) 还调节表达 α1 亚基的 GABAA 受体上 GABA 诱导的氯通量 (EC50= 137 nM)。FG 7142 (ZK 39106; LSU-65) 可以增加酪氨酸羟化并导致小鼠大脑皮层中 β-肾上腺素受体的上调。 | |||
| M42177 | SCS | SCS | GABA Receptor |
| SCS (Salicylidene salicylhydraide) 是一种有效的、变构的、选择性的 β1-containing GABAA receptors 的抑制剂，通过 VIPR 测量，对 α2β1γ1θ 的 IC50 为 32 nM。 | |||
| M42188 | Xilmenolone | Xilmenolone | GABA Receptor |
| Xilmenolone is a GABAA receptor positive allosteric modulator.。 | |||
| M56479 | Phaclofen | Phaclofen | GABA Receptor |
| Phaclofen 是一种选择性 GABAB receptor 拮抗剂。Phaclofen 是一种外周和中央的 baclofen 拮抗剂。 | |||
