找到约 56 条 “Rosin” 相关结果 （用时 0.074 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M4530
|
Rosin | 松香 | Others |
| Rosin 是从松木或松树桩中分离出来的，Rosin 是一种频繁接触的过敏原 (allergen)，可引起过敏性接触性皮炎。 | |||
| M6134
|
Tildipirosin | 泰地罗新 | Antibiotic |
| Tildipirosin是天然化合物泰乐菌素的衍生物。 | |||
| M8729
|
Syrosingopine | 乙酯利血平 | Others |
| Syrosingopine is an antihypertensive agent related to reserpine that was found to potentiate the anticancer effects of the antidiabetic agent metformin and phenformin without harmful effects on normal cells. | |||
M8974
|
ALW-II-41-27 | ALW-II-41-27 | Ephrin Receptor |
| Eph receptor tyrosine kinase inhibitor | |||
| ALW-II-41-27是一种有效的EPH家族激酶抑制剂，作用于EPHA2，IC50值为11 nM。 | |||
| M9403
|
TPI-1 | TPI-1 | Phosphatase |
| Tyrosine Phosphatase Inhibitor 1 | |||
| TPI-1是一种SHP-1的抑制剂，它抑制重组SHP-1的IC50值为40 nM。 | |||
| M10524
|
L-Tyrosine | L-酪氨酸；酪氨酸 | Others |
| L-Tyrosine是一种非必需氨基酸，是机体多种生成物的原料，酪氨酸在体内可通过不同代谢途径转化为多种生理物质，如多巴胺、肾上腺素、甲状腺素、黑色素等，这些物质与神经传导和代谢调节控制关系密切。 | |||
| M11262
|
MHP | MHP | SPHK |
| Methyl caprooyl tyrosinate | |||
| MHP (Methyl caprooyl tyrosinate) 是一种鞘氨醇激酶 (SPHK1) 激活剂，可显著增加 CAMP mRNA 和蛋白水平。MHP (Methyl caprooyl tyrosinate) 可增强抗微生物防御能力和先天免疫力。 | |||
| M14141 | Tephrosin | 灰叶草素 | EGFR/HER2 |
| Deguelinol I; Hydroxydeguelin | |||
| Tephrosin 是一种天然类胡萝卜素，具有较强的抗肿瘤活性。Tephrosin 通过诱导受体内化来诱导 EGFR 和 ErbB2 的降解。 | |||
| M14991
|
Demethylsuberosin | 7-去甲基软木花椒素 | Others |
| 7-Demethylsuberosin | |||
| Demethylsuberosin (7-Demethylsuberosin) 从 Angelica gigas Nakai 中分离出的香豆素类化合物，具有抗炎活性。 | |||
| M16324 | Suberosin | 软木花椒素 | Coumarins |
| Suberosin 软木花椒素 | |||
| M16668 | 11-Hydroxytephrosin | 11-羟基灰叶素 | Flavonoids |
| 11-Hydroxytephrosin 11-羟基灰叶素 | |||
| M17346 | Androsin | 草夹竹桃苷 | Phenols |
| Androsin 草夹竹桃苷 | |||
| M17485 | Epipterosin L 2'-O-glucoside | Epipterosin L 2'-O-glucoside | Sesquiterpenoids |
| Epipterosin L 2'-O-glucoside | |||
| M17494 | Pterosin L 2'-O-glucoside | Pterosin L 2'-O-glucoside | Sesquiterpenoids |
| Pterosin L 2'-O-glucoside | |||
| M17500 | Norpterosin B glucoside | Norpterosin B glucoside | Sesquiterpenoids |
| Norpterosin B glucoside | |||
| M17558 | Epipterosin L | Epipterosin L | Sesquiterpenoids |
| Epipterosin L | |||
| M17559 | Norpterosin B | 去甲蕨素 B | Sesquiterpenoids |
| Norpterosin B 去甲蕨素 B | |||
| M17583 | Pterosin B | 蕨素B | Sesquiterpenoids |
| Pterosin B 蕨素B | |||
| M18764 | Terrestrosin D | 蒺藜皂苷D | Others |
| Terrestrosin D 蒺藜皂苷D | |||
| M18797 | Terrestrosin K | 蒺藜皂苷K | Others |
| Terrestrosin K 蒺藜皂苷K | |||
| M18948 | Cararosinol A | 香蒜酚 A | Others |
| Cararosinol A 香蒜酚 A | |||
| M19070
|
Erythrosin B sodium | 赤藓红 | Others |
| Erythrosin B sodium 赤藓红是一种合成偶氮染料，通常用作食品着色剂和纺织染料。它是一种水溶性化合物，可产生鲜红色。 | |||
| M20883 | 3-Nitro-L-tyrosine | 3-Nitro-L-tyrosine | Adrenergic Receptor |
| 3-NT, N-Tyr, MNT | |||
| 3-Nitro-L-tyrosine (3-NT, N-Tyr, MNT), synthesized from L-tyrosine by peroxynitrite, is a product of nitric oxide and superoxide. 3-Nitro-L-tyrosine inhibits the hemodynamic responses to angiotensin II, possibly through the inhibition of alpha 1-adrenoceptor-mediated events. | |||
| M21641
|
O-Phospho-L-tyrosine | L-磷酸酪氨酸 | Peptides |
| H-Tyr(H2PO3)-OH; L-Tyrosine-O-phosphate | |||
| L-磷酸酪氨酸是一种酪氨酸磷酸化研究中的有用试剂，与某些RNA肿瘤病毒与细胞的恶性转化有关。 | |||
| M21700
|
Recombinant Human Asprosin (HEK293, N-8His) | 重组人Asprosin 蛋白 (HEK293, N-8His) | Cytokines and Growth Factors |
| Fibrillin-1; FBN1 | |||
| Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. | |||
| M27653 | Tyrosine kinase inhibitor | Tyrosine kinase inhibitor | c-Met |
| Tyrosine kinase inhibitor 是一种有效的酪氨酸激酶抑制剂。 | |||
| M30328 | L-m-Tyrosine | L-m-Tyrosine | Others |
| L-m-Tyrosine 是一种非天然氨基酸，有潜力用于帕金森氏病，阿尔茨海默氏病和关节炎的研究。 | |||
| M39181 | D-Tyrosine | D-酪氨酸 | Tyrosinase |
| D-Tyrosine 是酪氨酸的 D-型异构体。D-Tyrosine 通过抑制酪氨酸酶 (tyrosinase) 活性来负调节黑色素的合成。 | |||
| M39344 | Boc-L-Tyrosine methyl ester | Boc-L-Tyrosine methyl ester | Amino Acid Derivatives |
| Boc-L-Tyrosine methyl ester 是一种酪氨酸衍生物。 | |||
| M39384 | O-Methyl-D-tyrosine | O-Methyl-D-tyrosine | Amino Acid Derivatives |
| O-Methyl-D-tyrosine 是一种酪氨酸衍生物。 | |||
| M2912
|
Pacritinib | 帕克替尼；帕瑞提尼 | JAK |
| SB1518 | |||
| Pacritinib (SB1518)是一种大环类化合物，同时也是有效的Janus Kinase 2 (JAK2)和Fms-Like Tyrosine Kinase-3 (FLT3)的选择性抑制剂，IC50分别为23 nM和22 nM。 | |||
| M4370
|
Trifolirhizin | 三叶豆紫檀苷 | Tyrosinase |
| Trifolirhizin 是从苦参根中分离出的一种 pterocarpan 黄酮类化合物。Trifolirhizin 具有高效的 tyrosinase 抑制活性，IC50 为 506 μM。Trifolirhizin 具有潜在的抗炎和抗癌活性。 | |||
| M4599
|
Arbutin | 熊果苷 | Others |
| p-Arbutin; β-Arbutin | |||
| Arbutin (β-Arbutin) 是一种从熊果植物 Arctostaphylos uvaursi 中分离出的天然多酚，具有抗氧化，抗炎和抗肿瘤特性。是黑色素细胞中酪氨酸酶 (tyrosinase) 的竞争性抑制剂，对单酚酶的 Kiapp 值为 1.42 mM；对二酚酶 Kiapp 的值为 0.9 mM。Arbutin 也用作脱色剂。 | |||
| M4875
|
UNC2881 | UNC2881 | TAM Receptor |
| UNC2881 is a specific Mer tyrosine kinase inhibitor with IC50 of 4.3 nM, about 83- and 58-fold selectivity over Axl and Tyro3, respectively | |||
| M4937
|
Icotinib Hydrochloride | 盐酸埃克替尼 | EGFR/HER2 |
| BPI-2009H | |||
| Icotinib Hcl(BPI-2009H) is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). | |||
| M5365
|
Monobenzone | 莫诺苯宗 | Animal Modeling |
| 4-(Benzyloxy)phenol | |||
| Monobenzone是一种有效的皮肤脱色剂，能特异性地抑制tyrosinase，可用于构建白癜风动物模型，以及用于皮肤色素脱失的相关研究。 | |||
| M9257
|
Evobrutinib | 埃沃布鲁替尼 | BTK |
| MSC-2364447C | |||
| Evobrutinib是一种高选择性的共价的BTK（Bruton's Tyrosine Kinase）抑制剂，IC50为8.9 nM。Evobrutinib常用于多发性硬化症（MS）等自身免疫性疾病的研究。Evobrutinib通过共价结合BTK，抑制B细胞受体（BCR）信号通路的激活，从而调节B细胞的发育、增殖和存活。此外，它还可以抑制巨噬细胞活性以及抗体和细胞因子的产生与释放，对适应性和先天性免疫系统均有影响。 | |||
| M6910
|
LM22A-4 | LM22A-4 | Trk |
| LM22A4 | |||
| LM22A-4 是一种有效的，特异性的 tyrosine kinase receptor B (TrkB) 激动剂，常用于神经系统疾病研究。 | |||
| M7753 | DAPH | DAPH | Others |
| DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR. | |||
| M7867
|
JNJ-10198409 | JNJ-10198409 | Others |
| JNJ-10198409 is a potent ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenic and a direct tumor cell antiproliferative activity. | |||
| M7872
|
Kojic acid | 曲酸 | NF-κB |
| Tyrosinase inhibitor（曲酸）是一种从真菌中分离出来的天然产物。也是NF-κb，儿茶酚氧化酶，酪氨酸酶和D-氨基酸氧化酶的抑制剂。抑制蘑菇酪氨酸酶的IC50值为6.1±0.4 μg/ml，具有抗肿瘤功能。 | |||
| M8043
|
PD-161570 | PD-161570 | Others |
| PD-161570 is an inhibitor of human FGF-1 receptor tyrosine kinase. | |||
| M8059 | PD-180970 | PD-180970 | Others |
| PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase. | |||
| M8061 | SU5614 | SU5614 | Others |
| SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases. | |||
| M8152 | ST638 | ST638 | Others |
| Protein tyrosine kinase inhibitor (IC50 = 370 nM). | |||
| M8296 | DMPQ dihydrochloride | DMPQ dihydrochloride | Others |
| DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC50 = 80 nM. | |||
| M8440 | PKI-166 | PKI-166 | Others |
| PKI-166 is a potent, selective and orally available EGF-R tyrosine kinase inhibitor. | |||
| M8813 | Tyrphostin AG 825 | Tyrphostin AG 825 | Others |
| EGF receptor tyrosine kinase inhibitor, inactive against IGF-1 Receptor. | |||
| M8820
|
Tyrphostin RG 14620 | Tyrphostin RG 14620 | Others |
| Tyrphostin RG14620 | |||
| Non-phenolic tyrphostin-class tyrosine kinase inhibitor. | |||
| M8827 | Tyrphostin 51 | Tyrphostin 51 | Others |
| Tyrphostin 51 is an EGFR tyrosine kinase inhibitor. | |||
| M9081
|
Sodium Stibogluconate | Sodium Stibogluconate | Phosphatase |
| Stibogluconate sodium | |||
| Sodium Stibogluconate是一种有效的蛋白酪氨酸磷酸酶protein tyrosine phosphatase 抑制剂。 | |||
| M58119
|
Metyrosine | 甲酪氨酸；α-甲基-L-酪氨酸 | COX |
| α-Methyl-L-tyrosine | |||
| Metyrosine 是一种选择性酪氨酸羟化酶 (tyrosine hydroxylase enzyme) 抑制剂。Metyrosine 显著抑制高 COX-2 活性。Metyrosine 具有抗炎和抗溃疡作用。 | |||
| M9465
|
MAZ51 | MAZ51 | VEGFR/PDGFR |
| MAZ-51 | |||
| MAZ51 is originally synthesized inhibitor of VEGFR-3 (Flt-4) tyrosine kinase, inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. | |||
| M10095
|
Orelabrutinib | 奥布替尼 | BTK |
| ICP-022 | |||
| Orelabrutinib (ICP-022)是一种有效的、口服活性的且不可逆的 Bruton's tyrosine kinase (BTK) 的抑制剂。可用于多发性硬化症（MS）的相关研究。 | |||
| M10386
|
MT-802 | MT-802 | PROTAC |
| MT-802 是一种基于PROTAC技术的BTK降解剂，可诱导 Bruton's tyrosine kinase (BTK) 的降解。MT-802 可将BTK募集到 cereblon E3 ubiquitin ligase complex 中，以通过蛋白酶体触发BTK泛素化和降解。 | |||
| M10497
|
ONO-7475 | ONO-7475 | TAM Receptor |
| ONO7475 | |||
| ONO-7475 是一种有效的，选择性的，具有口服活性的 Anexelekto (Axl) / MER tyrosine kinase 抑制剂，IC50值分别为0.7 nM和1.0 nM。 | |||
