找到约 30 条 “Calcium Channel” 相关结果 （用时 0.282 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M2248
|
Cilnidipine | 西尼地平 | Calcium Channel |
| FRC 8653 | |||
| Cilnidipine是一种钙离子通道（Calcium Channel）抑制剂。 | |||
| M2820
|
Lomerizine dihydrochloride | 盐酸洛美利嗪 | Calcium Channel |
| KB-2796 | |||
| Lomerizine 2HCl是一种相对新型L-和T-型钙通道（Calcium Channel）阻滞剂。 | |||
| M3118
|
Verapamil hydrochloride | 盐酸维拉帕米 | Calcium Channel |
| (±)-Verapamil hydrochlorid; CP-16533-1 hydrochloride | |||
| Verapamil hydrochloride是一种具有口服活性的L-型钙通道（Calcium Channel）抑制剂，可以消除钙通道激动剂诱导的钙内流和细胞凋亡。Verapamil hydrochloride 也是一种有效的口服活性的第一代 P 糖蛋白 (P-gp) 抑制剂。维拉帕米能抑制 CAT1 介导的精氨酸、高精氨酸和 ADMA 的吸收，其 IC50 值分别为 85.3、58.1 和 113 µM。 | |||
| M3296
|
Manidipine dihydrochloride | 盐酸马尼地平 | Calcium Channel |
| CV-4093 | |||
| Manidipine 2HCl是Manidipine的盐酸盐形式，是钙通道（Calcium Channel）阻断剂，IC50为2.6 nM。 | |||
| M3498
|
Nimodipine | 尼莫地平 | Calcium Channel |
| BAY-e 9736 | |||
| Nimodipine是一种具有口服活性的二氢吡啶钙拮抗剂，是钙离子通道抑制剂（Calcium Channel）Nifedipine的类似物，具有降压活性。Nimodipine能减少细胞内游离Ca2+，Beclin-1及细胞自噬。 | |||
| M3500
|
Diltiazem hydrochloride | 盐酸地尔硫卓；地尔硫；硫氮卓酮；恬尔心； | Calcium Channel |
| CRD-401 | |||
| Diltiazem hydrochloride（地尔硫，硫氮卓酮，恬尔心，酸地尔硫卓）是一种钙通道（Calcium Channel）阻滞剂，对细胞外钙离子的跨膜流入具有抑制作用，可用于肿瘤及心血管疾病的相关研究。 | |||
| M3613
|
NP118809 | NP118809 | Calcium Channel |
| 39-1B4, NP-118809 | |||
| NP-118809 (39-1B4)是一种有效的n型钙通道（Calcium Channel）阻滞剂(IC50= 0.11 uM);l型钙通道具有良好的选择性。 | |||
| M4968
|
Mitiglinide calcium hydrate | 米格列奈钙 | Potassium Channel |
| KAD-1229 calcium hydrate; S-21403 calcium hydrate | |||
| Mitiglinide calcium hydrate is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. | |||
M5073
|
(R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 | Calcium Channel |
| (R)-(+)-Bay-K-8644; R-4407; NI-105; (+)-BAY-K-8644; Bayk8644 | |||
| (R)-(+)-BAY K 8644 是一种钙通道（calcium channel）抑制剂，抑制 Ba2+电流 (IBa) ，IC50为975 nM。同时，(R)-(+)-BAY K 8644也是一种有效的TMEM176B抑制剂。此外，(R)-(+)-BAY K 8644还能提高Oct4和Klf4对小鼠成纤维细胞的重编程效率，弥补Sox2缺失带来的影响。 | |||
| M5080
|
Efonidipine hydrochloride | 依福地平盐酸盐 | Calcium Channel |
| NZ-105 | |||
| Efonidipine Hcl is a dual T-type and L-type calcium channel blocker . | |||
| M5139
|
Amlodipine | 氨氯地平 | Calcium Channel |
| UK-48340 | |||
| Amlodipine 是一种具有口服活性的二氢吡啶钙通道（Calcium Channel）阻滞剂，通过阻断电压依赖性的 L 型钙通道，从而抑制钙离子内流。 | |||
| M5756
|
L-Phenylalanine | L-Phenylalanine | Calcium Channel |
| (S)-2-Amino-3-phenylpropionic acid | |||
| L-Phenylalanine (L-苯丙氨酸)是α2δ钙离子通道（Calcium Channel）拮抗剂，Ki为980 nM。 | |||
| M6499
|
Bepridil hydrochloride | 盐酸贝普地尔 | Calcium Channel |
| CERM 1978 | |||
| Bepridil hydrochloride (CERM 1978) 是一种钙离子通道 (calcium channel) 抑制剂，可以用于心绞痛的研究。 | |||
| M7723 | CBIQ | CBIQ | Others |
| CBIQ is an activator of the cystic fibrosis transmembrane conductance regulator (CFTR) and the intermediate-conductance calcium-sensitive K+ channel (KCNN4). | |||
| M7898 | Lidoflazine | 利多氟嗪 | Others |
| Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia. | |||
| M8315 | Ralfinamide mesylate | Ralfinamide mesylate | Others |
| Ralfinamide is a mixed sodium and N-type calcium channel blocker. | |||
| M8330 | Carboxyamidotriazole | Carboxyamidotriazole | Others |
| Carboxyamidotriazole (L-651582) is an orally active calcium channel blocker. | |||
| M8515 | Nifetepimine | Nifetepimine | Others |
| Nifetepimine is a dihydropyrimidone calcium channel blocker that down-modulates SERCA3 (sarco/endoplasmic reticulum Ca2+ -ATPase 3) pump, and protects of the CD4+ T cells from tumor-induced apoptosis. | |||
| M14189
|
Amlodipine maleate | 马来酸氨氯地平 | Calcium Channel |
| Amlodipine maleate 是二氢吡啶类钙通道 (calcium channel) 阻滞剂，作为一种具有口服活性的抗心绞痛试剂 (antianginal agent)。Amlodipine maleate 阻断了电压依赖性的 L 型钙通道，从而抑制了钙离子内流。Amlodipine maleate 可用于高血压和癌症的研究。 | |||
| M14201
|
Mibefradil dihydrochloride | 盐酸米贝地尔 | Calcium Channel |
| Ro 40-5967 dihydrochloride | |||
| Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) 是一种钙离子通道 (calcium channel) 抑制剂，选择性作用于 T 型 Ca2+通道，作用于 T 型和 L 型通道，IC50 分别为 2.7 μM 和 18.6 μM。 | |||
| M14203 | Norverapamil hydrochloride | 盐酸去甲维拉帕米 | Calcium Channel |
| (±)-Norverapamil hydrochloride; D591 hydrochloride | |||
| Norverapamil hydrochloride，是 Verapamil 的 N-去甲基代谢物，是一种钙通道 (L-type calcium channel) 阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。 | |||
| M14204
|
Verapamil | 维拉帕米 | Calcium Channel |
| (±)-Verapamil; CP-16533-1 | |||
| Verapamil ((±)-Verapamil) 是一种钙通道 (calcium channel) 阻滞剂，是一种有效的口服活性的第一代 P 糖蛋白 (P-gp) 抑制剂。Verapamil 能也抑制 CYP3A4，并可用于高血压，心律不齐和心绞痛的研究。 | |||
| M14514
|
N-(p-amylcinnamoyl) Anthranilic Acid | N-(p-amylcinnamoyl) Anthranilic Acid | Phospholipase |
| ACA | |||
| N-(p-amylcinnamoyl) Anthranilic Acid (ACA) 是一种广谱磷脂酶 A2 (PLA2) 的抑制剂，TRP channel的阻滞剂。N-(p-amylcinnamoyl) Anthranilic Acid (ACA) 也是一种有效的钙离子激活氯通道 (calcium-activated chloride channels) 的可逆抑制剂，有潜力用于心律失常的相关研究。 | |||
| M16986
|
Kobusin | 去甲槟郎碱 | GLUT |
| Kobusin（去甲槟郎碱）是从 Pnonobio biondii Pamp 分离的双环氧木脂素，同时也是 CFTR 和 CaCCgie 氯化物通道的激活剂，以及ANO1/CaCC (calcium-activated chloride channel) 通道的抑制剂。 | |||
| M18297
|
14-Deoxyandrographolide | 14-去氧穿心莲内酯 | Calcium Channel |
| 14-Deoxyandrographolide 是一种具有钙通道 (calcium channel) 阻断活性的劳丹脂二萜。 | |||
| M20409 | Levamlodipine | Levamlodipine | Calcium Channel |
| S-amlodipine | |||
| Levamlodipine is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure. | |||
| M20441
|
Efonidipine | Efonidipine | Calcium Channel |
| NZ-105 | |||
| Efonidipine is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal. | |||
| M20469 | Nicardipine | Nicardipine | Others |
| YC-93 | |||
| Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. | |||
| M20576 | Pinaverium bromide | Pinaverium bromide | Calcium Channel |
| icosapentaenoic acid | |||
| Pinaverium bromide acts as a calcium channel blocker and is useful for functional gastrointestinal disorders. | |||
| M20928 | Lanthanum(III) chloride heptahydrate | Lanthanum(III) chloride heptahydrate | Calcium Channel |
| Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels. | |||
