找到约 40 条 “Antibiotic” 相关结果 （用时 0.159 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M1831
|
Cyclosporine A | 环孢菌素 A；环胞霉素A；环孢素A | Immunology/Inflammation |
| Ciclosporin A; CsA; Cyclosporin A; Antibiotic S 7481F1 | |||
| Cyclosporine A （环胞霉素A; 环孢菌素 A; CsA; Cyclosporin A）是一种免疫抑制剂和钙调素磷酸酶抑制剂，Cyclosporine A能够抑制T淋巴细胞的增殖和分化，以及抑制IL-2、IFN-γ等细胞因子的分泌，目前主要用于狼疮肾炎、风湿性关节炎、银屑病等炎症性和自身免疫性疾病的研究，以及器官移植研究。 | |||
| M2790
|
K252a | K252a | PKC |
| SF 2370; Antibiotic K-252a; Antibiotic SF 2370 | |||
| K252a 是BDNF 受体 TrkB 的抑制剂。K-252a 对 PKC、PKA、II型钙调素依赖性激酶和磷酸化酶激酶的 IC50 值分别为470 nM、140 nM、270 nM和1.7 nM。K-252a 抑制 NGF 受体 gp140trk 的酪氨酸蛋白激酶 (TRK) 活性，IC50 为 3 nM。 | |||
M6292
|
Ansamitocin P 3 | 安丝菌素P-3 | Microtubule |
| Antibiotic C 15003P3; Maytansinol butyrate | |||
| Ansamitocin P-3是一种微管抑制剂，也是一种大环抗肿瘤抗生素。 | |||
| M9780
|
Nigericin | 尼日利亚霉素；尼日利亚菌素 | Potassium Channel |
| Antibiotic K178, Antibiotic X464 | |||
| Nigericin 是一种抗生素 (antibiotic)，源自 Streptomyces hygroscopicus，充当 K+/H+ 离子载体 (K+/H+ ionophore)，促进 K+/H+ 跨线粒体膜交换。Nigericin 是 NLRP3 的激活剂。 | |||
| M9860
|
Bleomycin A5 Hydrochloride | 盐酸平阳霉素 (不含铜离子) | DNA/RNA Synthesis |
| BLEOCIN Antibiotic; Bleomycin A5 HCl | |||
| 博莱霉素A5盐酸盐是博莱霉素家族的一种独特的抗生素，对真核和原核细胞有毒。 | |||
| M11236
|
Lasalocid sodium | 拉沙洛西钠；拉沙里菌素钠；那塞罗钠 | Antibiotic |
| Lasalocid-A sodium; Ionophore X-537A sodium; Antibiotic X-537A | |||
| Lasalocid sodium (Lasalocid-A sodium) 是一个抗菌剂。 | |||
| M13469 | Lasalocid | Lasalocid | Antibiotic |
| Lasalocid-A; Ionophore X-537A; Antibiotic X-537A | |||
| Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) 是一种抗菌剂和抗球虫药, 用在饲料添加剂中。 | |||
| M21494
|
Sibofimloc | Sibofimloc | Antibiotic |
| Antibiotic-202 | |||
| Sibofimloc (Antibiotic-202) 是一类首创的(first-in-class)，肠道限制性的，具有口服活性的 FimH 粘附 (FimH adhesion ) 抑制剂。Sibofimloc 具有抗细菌感染活性，被开发用于炎症性肠病 (IBD) 的研究。 | |||
| M30025 | Malonomicin | Malonomicin | Antibiotic |
| Antibiotic K16 | |||
| Malonomicin (Antibiotic K16) 是一种具有抗原生动物和抗锥虫活性的抗生素。Malonomicin 在体内也显示出抗锥虫活性。 | |||
| M30504 | Pentachloropseudilin | Pentachloropseudilin | Myosin |
| Antibiotic A 15104 Y; PClP | |||
| Pentachloropseudilin (Antibiotic A 15104 Y; PClP) 是一种可逆的、变构有效的肌球蛋白 (Myo1s) 抑制剂，对 Myo1s 的 IC50 范围为 1 至 5 μM，对于 2 类和 5 类肌球蛋白，IC50 范围 > 90 μM。Pentachloropseudilin 是转化生长因子-β (TGF-β) 刺激的信号传导的有效抑制剂，对 TGF-β 的 IC50 值为 0.1-0.2 μM。 | |||
| M30588 | Leucinostatin A | Leucinostatin A | Antifungal |
| Antibiotic P168 | |||
| Leucinostatin A (Antibiotic P168) 是一种九肽，对白色念珠菌和新型隐球菌具有显着的活性。Leucinostatin A 是一种疏水性九肽抗生素。Leucinostatin A 通过减少前列腺基质细胞中胰岛素样生长因子-I 的表达来抑制前列腺癌的生长。具有抗原虫活性。 | |||
| M58313
|
Antibiotic PF 1052 | 抗菌素 PF 1052 | Antibiotic |
| PF1052 | |||
| Antibiotic PF 1052 是一种从天然产物库中筛选出的具有有效抗炎活性的抗生素。Antibiotic PF 1052 对小鼠中性粒细胞迁移有抑制作用。 | |||
| M2637
|
Difloxacin hydrochloride | 盐酸双氟沙星 | Antibiotic |
| Difloxacin is a synthetic antibiotic that belongs to the fluoroquinolone class. | |||
| M2833
|
Meclocycline Sulfosalicylate | 甲环素磺基水杨酸盐；磺基水杨酸甲氯环素；甲氯环素磺基水杨酸盐 | Antibiotic |
| Meclocycline is a tetracycline antibiotic. Meclocycline sulfosalicylate prevents bacterial protein synthesis through 30S ribosome-mediated chain elongation and blocks amino-acyl tRNA A-site binding. | |||
| M2950
|
Piromidic Acid | 吡咯酸；吡咯米酸 | Antibiotic |
| Piromidic acid is a quinolone antibiotic. | |||
| M3090
|
Trimethoprim | 甲氧苄啶 | Antifolate |
| Trimethoprim 是一种具有口服活性的抗菌剂（Antibiotic），可以通过抑制细菌的二氢叶酸还原酶（DHFR）来发挥抗菌作用。Trimethoprim对多种革兰氏阳性菌和革兰氏阴性需氧菌具有抑制活性，可用于尿路感染、志贺氏菌病和肺孢子菌肺炎的研究。Trimethoprim可诱导大肠杆菌细胞中的蛋白质聚集和热休克蛋白（HSPs）的表达。 | |||
| M3644
|
Demeclocycline hydrochloride | 盐酸地美环素 | Antibiotic |
| Demeclocycline HCl | |||
| Demeclocycline HCl 是一种四环素antibiotic可抑制细菌的蛋白合成，能用于细菌感染的相关研究。 | |||
| M4904
|
Clindamycin Phosphate | 克林霉素磷酸酯 | Antibiotic |
| NSC 618653 | |||
| Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. | |||
| M4906
|
Doripenem Hydrate | 多尼培南 | Antibiotic |
| S-4661 | |||
| Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections. | |||
| M4941
|
Lomefloxacin | 洛美沙星 | Antibiotic |
| Maxaquin,SC47111A | |||
| Lomefloxacin (SC47111A) 是一种广谱喹诺酮类 (antibiotic)抗生素，具有抗菌活性。 | |||
| M4947
|
Streptomycin sulfate | 硫酸链霉素 | Antibiotic |
| Streptomycin sulfate（硫酸链霉素）是一种氨基糖苷类抗生素（antibiotic），它通过抑制蛋白质合成中的起始和延伸过程来发挥作用。 | |||
| M6171
|
Solithromycin | 索利霉素 | Antibiotic |
| CEM-101; OP-1068 | |||
| Solithromycin（索利霉素，CEM-101）是一种大环内酯类抗生素（Antibiotic）。Solithromycin对链球菌属（包括肺炎链球菌）、流感嗜血杆菌、卡他莫拉菌、肺炎支原体和肺炎衣原体、耐甲氧西林金黄色葡萄球菌等均具有抑制活性。Solithromycin 常用于社区获得性肺炎（CAP）、皮肤感染等动物模型的研究。 | |||
| M7125 | PF 945863 | PF 945863 | Others |
| PF 945863 is a macrolide antibiotic. | |||
| M7436 | Trovafloxacin mesylate | 曲伐沙星甲磺酸盐；曲伐沙星甲磺酸 | Others |
| Trovafloxacin mesylate is a antibiotic; inhibits bacterial DNA synthesis. | |||
| M7721 | Chrysomycin B | 金黄霉素B | Others |
| Antibiotic from Streptomyces sp. | |||
| M7756 | Dihydroeponemycin | Dihydroeponemycin | Others |
| Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus. | |||
| M7893 | Leptomycin A | 来普霉素A | Others |
| Leptomycins are antifungal antibiotics with unique unsaturated, branched-chain fatty acid structures. | |||
| M7963
|
Nalidixic acid sodium salt | 萘啶酮酸钠 | Antibiotic |
| Nalidixic acid sodium salt 是一种喹诺酮类抗生素 (antibiotic)，对革兰氏阳性和革兰氏阴性细菌均有效。Nalidixic acid sodium salt 在较低浓度下以抑菌的方式起作用，而在较高浓度下具有杀菌作用。 | |||
| M8006 | PD 404,182 | PD 404,182 | Others |
| Potential antibiotic of gram negative bacteria. | |||
| M8276
|
Pleuromutilin | 泰妙菌素 | Antibiotic |
| Drosophilin B; Mutilin 14-glycolate | |||
| Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation. | |||
| M8378 | DCAP | DCAP | Others |
| DCAP is a potent broad-spectrum antibiotic that specifically targets the membranes of both Gram-positive and Gram-negative bacteria. | |||
| M8412 | Pivmecillinam | 匹美西林；氮卓脒青霉素双酯；吡呋氮卓脒青霉素 | Others |
| Amdinocillin pivoxil | |||
| Pivmecillinam is a gram negative antibiotic, and inhibitor of penicillin-binding protein 2 (PBP2). | |||
| M8417 | Geldanamycin-Biotin | Geldanamycin-Biotin | Others |
| Geldanamycin-Biotin is a benzoquinone ansamycin antitumor antibiotic. | |||
| M8578 | Undecylprodigiosin hydrochloride | Undecylprodigiosin hydrochloride | Others |
| Undecylprodigiosin is a tri-pyrolle antibiotic isolated from Streptomyces coelicolor A3 that exhibits immunosuppressive and apoptotic activities as well as antibacterial, antioxidative and UV protective properties. | |||
| M19137
|
Amoxicillin | 阿莫西林 | Antibiotic |
| Amoxicillin (Amoxycillin) 是一种具有良好口服吸收和广谱抗菌活性的抗生素 (antibiotic)。Amoxicillin 抑制细胞壁中多肽的生物合成，从而抑制细胞生长。 | |||
| M19865
|
Sulfacetamide sodium salt hydrate | Sulfacetamide sodium salt hydrate | Autophagy |
| Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. | |||
| M19867
|
Gatifloxacin hydrochloride | Gatifloxacin hydrochloride | Topoisomerase |
| AM-1155 hydrochloride; CG5501 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride | |||
| Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively. | |||
| M19876
|
Acetylspiramycin (ASPM) | 乙酰螺旋霉素 | Antibiotic |
| Spiramycin II; Foromacidin B; Spiramycin B | |||
| Acetylspiramycin (ASPM) 是一种有效的，具有口服活性的大环内酯抗生素 (antibiotic)，由多种链霉菌产生，对革兰氏阳性菌(包括化脓性链球菌、绿链球菌、白喉棒状杆菌和对甲氧西林敏感的金黄色葡萄球菌)具有有效的抗菌活性。此外，Acetylspiramycin 也是一种抗原虫剂，具有抗寄生虫活性。 | |||
| M19877
|
Kitasamycin | Kitasamycin | Antibiotic |
| leucomycin | |||
| Kitasamycin is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens. | |||
| M19879
|
Sulfachloropyridazine | 磺胺氯哒嗪 | Antibiotic |
| Sulfachloropyridazine（磺胺氯吡嗪）是一种合成的抗菌剂，属于磺胺类抗生素（Antibiotic）。Sulfachloropyridazine通过抑制细菌的二氢叶酸合成酶（DHFR），阻止叶酸的合成，从而抑制细菌的生长和繁殖。Sulfachloropyridazine可用于抑制革兰氏阳性和革兰氏阴性好氧细菌的生长。 | |||
