找到约 32 条 “6-FAM” 相关结果 （用时 0.213 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M4827
|
5(6)-Carboxyfluorescein | 5(6)-羧基荧光素 | Fluorescent Dye |
| 5(6)-FAM; 5,6-CF | |||
| 5(6)-Carboxyfluorescein（5(6)-羧基荧光素，5(6)-FAM）是一种pH敏感型荧光探针，其最大发射光的波长随pH值的改变而发生变化，可用于监测细胞内外pH值的变化。5(6)-Carboxyfluorescein也可用于标记蛋白质、多肽和氨基酸。在动物实验中，5(6)-Carboxyfluorescein 可用于肿瘤成像。 | |||
| M5930
|
Rifampicin | 利福平；利福霉素 | DNA/RNA Synthesis |
| NSC-113926; Rimactane; Rifamycin; Rifadin; Rifater | |||
| Rifampin 是一种大环类化合物，同时也是有效的广谱抗生素和DNA依赖性的RNA聚合酶抑制剂，可抑制RNA合成（RNA Synthesis），并能抵抗细菌病原体。 | |||
| M11928 | ChemBridge-5259046 | ChemBridge化合物-5259046 | Screening Compounds and Building Blocks |
| N-(3,6-dichloro-2-pyridinyl)-N'-{[(4,6-diphenyl-2-pyrimidinyl)amino]carbonyl}sulfamide (5259046) | |||
| ChemBridge特有类药化合物/先导化合物-5259046，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M21710
|
6-FAM | 6-羧基荧光素 | Fluorescent Dye |
| 6-Carboxyfluorescein; 6-CF | |||
| 6-FAM (6-Carboxyfluorescein) 是羧基荧光素的一个同分异构体，主要用于核酸的测序和标记。 | |||
| M21712
|
6-FAM SE | 6-FAM SE | Fluorescent Dye |
| 6-FAM SE是羧基荧光素的同分异构体。6-FAM SE主要被用于核酸测序和标记核苷酸。 | |||
| M21715
|
5(6)-FAM SE | 5(6)-FAM SE | Fluorescent Dye |
| 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers | |||
| 5(6)-FAM SE是一种胺反应的绿色荧光染料，广泛用于标记蛋白质或其他含有一级或二级脂肪胺的分子。 | |||
| M51743 | 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) | 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) | Others |
| 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) (6-FAM-AEEAC-SHK) 是一种多肽，可作为生化分析试剂 (Biochemical Assay Reagents)。 | |||
| M6704
|
EHT 1864 2HCl | EHT 1864 2HCl | Ras |
| EHT 1864 是一种有效的 Rac family small GTPases 的抑制剂。EHT 1864 直接结合并削弱了这种 small GTPase 与生长转化所需的关键下游效应器结合的能力。EHT 1864 结合 Rac1、Rac1b、Rac2 和 Rac3 的 Kd 值分别为 40、50、60 和 230 nM。此外，EHT1864可通过阻止液泡的形成，来抑制细胞的巨泡式死亡(methuosis)。 | |||
| M7197 | RMM 46 | RMM 46 | Others |
| RMM 46 is a mSK/RSK family kinase inhibitor. | |||
| M8639 | STK16-IN-1 | STK16-IN-1 | Others |
| STK16-IN-1 is a cell-permeable pyrrolonaphthyridinone compound that acts as an ATP-competitive inhibitor against NAK (Numb Associated Kinase) family serine/threonine kinase STK16 (IC50/substrate = 0. | |||
| M40806
|
Anti-Mouse NK1.1 Antibody In vivo | Anti-Mouse NK1.1 Antibody In vivo | Others |
| This NK1.1 antibody (clone PK136) recognizes mouse NK1.1. NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. | |||
| M14778 | Tafamidis meglumine | 他发米帝司甲葡胺 | Transthyretin (TTR) |
| Fx-1006A | |||
| Tafamidis meglumine (Fx-1006A) 是一种有效、选择性的 transthyretin (TTR) 稳定剂，对野生型 WT-TTR 和突变型同源四聚体 V30M-TTR，V122I-TTR 的活性相当，EC50 值为 2.7-3.2 μM。Tafamidis meglumine 抑制淀粉样蛋白的生成。 | |||
| M19949
|
Phloracetophenone | Phloracetophenone | Cytochrome P450 (e.g. CYP17) |
| 2,4,6-trihydroxyacetophenone | |||
| Phloracetophenone, or 2,4,6-trihydroxyacetophenone (THA), the aglycone component of phloracetophenone glucoside, is a naturally occurring compound obtained from the rhizome of Curcuma comosa (Family Zingiberaceae). | |||
| M19986
|
Recombinant Human CXCL6 (HEK293, C-6His) | 重组人CXCL6 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| C-X-C Motif Chemokine 6; Chemokine Alpha 3 | |||
| Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162. | |||
| M21402
|
Recombinant Mouse IL-27 (HEK293, C-6His) | 重组小鼠IL-27 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| Interleukin-27 subunit alpha; IL-27 subunit alpha | |||
| IL-27 is a heterodimeric cytokine which belongs to the IL-6/IL-12 family of long type I cytokines. Recombinant Mouse Interleukin-27 Subunit Alpha and Interleukin-27 Subunit Beta expressed the target gene encoding Tyr19-Pro228&Phe29-Ser234 with a 6His tag at the C-terminus. | |||
| M25175 | Cirevetmab | Cirevetmab | TGF-beta/Smad |
| ZTS-00521426 | |||
| Cirevetmab (ZTS-00521426) 是一种免疫球蛋白 G2-kappa，Canis lupus familiaris TGFB1 犬源化单克隆抗体。Cirevetmab 是一种免疫调节剂。 | |||
| M27701 | Famitinib | 法米替尼 | VEGFR/PDGFR |
| SHR1020 | |||
| Famitinib (SHR1020) 是一种有效的，具有口服活性的多靶点激酶抑制剂，抑制 c-kit, VEGFR-2 和 PDGFRβ 的活性，IC50 值分别为 2.3 nM、4.7 nM 和 6.6 nM。Famitinib具有抗肿瘤活性。且诱导细胞凋亡 (apoptosis)。 | |||
| M28063 | Famitinib malate | Famitinib malate | VEGFR/PDGFR |
| SHR1020 malate | |||
| Famitinib (SHR1020) malate 是一种有效的，具有口服活性的多靶点激酶抑制剂，抑制 c-kit，VEGFR-2 和 PDGFRβ 的活性，IC50 值分别为 2.3 nM、4.7 nM 和 6.6 nM。Famitinib malate 诱导细胞凋亡 (apoptosis)。Famitinib malate 具有抗肿瘤活性，可用于癌症的研究。 | |||
| M30415 | Oxiconazole | 奥昔康唑 | Antifungal |
| Ro 13-8996 free base | |||
| Oxiconazole (Ro 13-8996) 是一种广谱抗真菌剂，能抑制念珠菌 (Candida)、曲霉属真菌 (Aspergillus) 和毛癣菌属真菌 (Trichophyton) 的生长。Oxiconazole 也是一种高效的 CYP3A4 反式激活剂，可与利福平 (Rifampicin) 竞争性拮抗。Oxiconazole 通过过氧化物酶 2 (PRDX2) 介导的细胞自噬 (autophagy) 停滞来发挥抗结直肠癌的作用。 | |||
| M30416
|
Oxiconazole nitrate | 硝酸奥昔康唑 | Antifungal |
| Ro 13-8996 | |||
| Oxiconazole (Ro 13-8996) nitrate 是一种广谱抗真菌剂，能抑制念珠菌 (Candida)、曲霉属真菌 (Aspergillus) 和毛癣菌属真菌 (Trichophyton) 的生长。Oxiconazole nitrate 也是一种高效的 CYP3A4 反式激活剂，可与利福平 (Rifampicin) 竞争性拮抗。Oxiconazole nitrate 通过过氧化物酶 2 (PRDX2) 介导的细胞自噬 (autophagy) 停滞来发挥抑制结直肠癌的作用。 | |||
| M31286 | 2-Amino-6-chloropurine | 2-氨基-6-氯嘌呤 | Others |
| 2-Amino-6-chloropurine（2-氨基-6-氯嘌呤）是一种嘌呤类衍生物，可用作有机合成与药物分子的合成中间体（如Famciclovir）。 | |||
| M40995
|
Recombinant Rat CXCL16 Protein (HEK293, C-His) | 重组大鼠CXCL16蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| chemokine (C-X-C motif) ligand 16 | |||
| C-X-C motif chemokine 16 (CXCL16) is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of bacterial products, with the properties of an adhesion molecule and inflammatory chemokine. | |||
| M43961
|
Recombinant Human Claudin-6/CLDN6 Full Length Protein (HEK293, VLP) | 重组人Claudin-6/CLDN6 蛋白 (HEK293, VLP) | Cytokines and Growth Factors |
| CLDN6 | |||
| Claudin-6 (CLDN6) belongs to the claudins family. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. | |||
| M45176
|
Recombinant Human B7-H3/CD276 Protein (HEK293, C-6His) | 重组人B7-H3/CD276 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| B7 homolog 3; CD276 antigen | |||
| B7-H3 (also known as CD276) is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is involved in the activation of T lymphocytes, and regulates murine bone formation. | |||
| M51442 | Orphan GPCR SP9155 agonist P550 (mouse, rat) | Orphan GPCR SP9155 agonist P550 (mouse, rat) | Others |
| Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat))，RFamide 肽家族的成员，具有促食欲作用，是小鼠孤儿受体 GPR103 的同源配体，也命名为 SP9155 或 AQ27。 | |||
| M51627 | 26Rfa, Hypothalamic Peptide, human | 26Rfa, Hypothalamic Peptide, human | Others |
| 26Rfa, Hypothalamic Peptide, human 是一种下丘脑神经肽，属于 RFamide 肽家族，具有促食欲活性。 | |||
| M54522
|
Recombinant Human IFN-α 2b Protein (E. coli) | 重组人IFN-α 2b 蛋白 (E. coli) | Cytokines and Growth Factors |
| Interferon-Alpha 2b | |||
| IFN-α 2b (Interferon-Alpha 2b) [Cys24-Glu188 (Lys46Arg)] produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections. | |||
| M54737
|
Recombinant Human GAD67 Protein (Baculovirus-Insect, C-His) | 重组人GAD67 蛋白 (Baculovirus-Insect, C-His) | Cytokines and Growth Factors |
| GAD1; Glutamate decarboxylase 1 | |||
| GAD67 (GAD1) is a member of thegroup II decarboxylase family. GAD67 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. | |||
| M55024
|
Recombinant Human DPP4/CD26 (HEK293, C-6His) | 重组人DPP4/CD26 (HEK293, C-6His) | Cytokines and Growth Factors |
| Dipeptidyl Peptidase 4; DPP IV; ADCP-2 | |||
| DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. | |||
| M55549
|
Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc) | 重组小鼠DPP-4/CD26 Protein (HEK293, N-hFc) | Cytokines and Growth Factors |
| Dipeptidyl Peptidase 4; DPP IV | |||
| Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). | |||
| M58156
|
Recombinant Human PRDX6 Protein (E. coli, N-6His) | 重组人PRDX6 蛋白 (E. coli, N-6His) | Cytokines and Growth Factors |
| Peroxiredoxin-6; 1-Cys Peroxiredoxin; Acidic Calcium-Independent Phospholipase A2 | |||
| Peroxiredoxin 6 (PRDX6) belongs to the thiol-specific antioxidant protein family, it is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin 6 may regulates phospholipid turnover and protectes against oxidative injury. | |||
| M58453
|
Recombinant Human BMP-6 (E.coli, C-His) | 重组人BMP-6 (E.coli, C-His) | Cytokines and Growth Factors |
| Bone Morphogenetic Protein-6 | |||
| Bone Morphogenetic Protein-6 (BMP-6) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-6 can bind with the TGF-β receptor and triggers SMAD protein signal transduction. It plays a vital role in regulating hepcidin to maintain iron ions in the body. | |||
