Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc) 别名：Dipeptidyl Peptidase 4; DPP IV; 重组小鼠DPP-4/CD26 Protein (HEK293, N-hFc)

目录号 M55549

Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV).

Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc)结构式

规格	价格	库存状态
50ug	¥ 4800	现货

本产品不参加促销活动

*AbMole所有产品仅供有资质的科研机构或医药企业进行科学研究或药证申报用途，不能被用于人体和任何其它用途。我们不向任何个人或非科研性质的机构提供产品和服务。

质量标准及产品资料

纯度：>95%, Endotoxin < 1 EU/µg
COA

化学性质/溶解性/储存

性状	Lyophilized powder
中文名称	重组小鼠DPP-4/CD26 Protein (HEK293, N-hFc)
溶解性	Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件	Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式	冰袋运输，根据产品的不同，可能会有相应调整。

生物活性

Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It's binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones.

The recombinant mouse Dpp4 (hFc Tag) consists 992 amino acids and predicts a molecular mass of 112.9 kDa. A DNA sequence encoding the mouse Dpp4 (Ser29-His760) was expressed with the Fc region of human IgG1 at the N-terminus.

Accession: NP_034204.1

Endotoxin < 1 EU/µg

Lyophilized from sterile PBS, pH 7.4.

实验参考

动物实验

建议您制定动物给药及实验方案时，尽量参考已发表的相关实验文献（溶剂种类及配比众多，简单地溶解目的化合物，并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题，未必能保证目的化合物在动物体内充分发挥生物学效用）。
体内实验的工作液，建议您现用现配，当天使用；如在配制过程中出现沉淀、析出现象，可以通过超声和（或）加热的方式助溶。
切勿一次性将产品全部溶解。