C-X-C motif chemokine 16 (CXCL16) is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of bacterial products, with the properties of an adhesion molecule and inflammatory chemokine.
别名：chemokine (C-X-C motif) ligand 16
C-X-C motif chemokine 16 (CXCL16) is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of bacterial products, with the properties of an adhesion molecule and inflammatory chemokine. CXCL16/SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor for oxidized low-density lipoprotein that is expressed in atherosclerotic lesions. CXCR6 and its ligand CXCL16 in regulating metastasis and invasion of cancer. CXCR6 and CXCL16 are up-regulated in multiple cancer tissue types and cancer cell lines relative to normal tissues and cell lines.
The recombinant rat CXCL16 comprises 183 amino acids and predicts a molecular mass of 20.4 kDa. A DNA sequence encoding the rat CXCL16 extracellular domain (Met 1-Ala 198) was expressed with a polyhistidine tag at the C-terminus.
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 42 kDa, reducing conditions
Lyophilized from sterile PBS, pH 7.4.
| 性状 | Lyophilized powder |
| 溶解性（25°C） | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| 储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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