找到约 46 条 “L-Cysteine” 相关结果 （用时 0.091 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M11366
|
Se-Methylselenocysteine | L-硒甲基硒代半胱氨酸 | Apoptosis |
| Methylselenocysteine; Se-Methylseleno-L-cysteine | |||
| Se-Methylselenocysteine，甲基硒的前体，具有强大的癌症化学预防活性和抗氧化活性。Se-Methylselenocysteine 具有口服生物活性，可诱导细胞凋亡 (apoptosis)。 | |||
| M3598
|
Penicillamine | D-青霉胺 | Others |
| DL-beta-Mercaptovaline, 3,3-Dimethyl-DL-cysteine, 3-Sulfanylvaline, Cuprimine, Depen, DL-PenA | |||
| Penicillamine（DPA，D-青霉胺）是一种具有口服活性的化合物，可以减少T淋巴细胞数量、抑制巨噬细胞功能、降低IL-1、减少类风湿因子和防止胶原交联。 | |||
M5385
|
Acetylcysteine (NAC) | N-乙酰-半胱氨酸；乙酰半胱氨酸 | ROS |
| N-Acetyl-L-cysteine; NAC; N-acetylcysteine; N-Acetyl-Cysteine | |||
| Acetylcysteine(NAC，N-acetyl-l-cysteine，N-乙酰-半胱氨酸)是一种ROS和肿瘤坏死因子（TNF）的抑制剂，同时可以拮抗多种蛋白酶体抑制剂的活性，此外Acetylcysteine还能裂解指甲角蛋白中胱氨酸的二硫键。 | |||
| M6899 | L-Cysteinesulfinic acid | L-半胱亚磺酸 | Others |
| L-Cysteinesulfinic acid is a nMDA and mGlu agonist. | |||
| M7588
|
N-acetylcysteine amide | N-乙酰-L-胱氨酸 | NF-κB |
| N-Acetylcysteine amide（NACA，N-乙酰-L-胱氨酸）是一种能透过细胞膜和血脑屏障的硫醇化合物，具有抗氧化和抗炎活性，以及神经保护功能，可以调节NF-κB和HIF-1α的活化，抑制ROS的产生。 | |||
| M8297 | S-Allyl-L-cysteine | S-烯丙基别半胱氨酸；蒜氨酸 | Others |
| S-allyl-L-cysteine is a sulfur containing amino acid found in garlic with antioxidant, anti-cancer, antihepatotoxic, neuroprotective and neurotrophic activity. | |||
| M9611
|
S-Adenosylhomocysteine | S-Adenosylhomocysteine | METTL3 |
| SAH; AdoHcy | |||
| S-Adenosylhomocysteine是半胱氨酸和腺苷合成的中间体，是一种METTL3-METTL14异二聚体复合物 (METTL3-14) 的抑制剂，其IC50值为 0.9 µM。 | |||
| M9806
|
L-Cysteine | L-半胱氨酸 | Animal Modeling |
| L-Cysteine（L-半胱氨酸）是一种含硫非必需氨基酸，同时也是肠道碱性磷酸酶(IAP)的抑制剂，能抑制胃饥饿素，可用于构建骨关节炎模型。 | |||
| M10973
|
N-Acetyl-D-cysteine | N-乙酰基-D-半胱氨酸 | ROS |
| N-Acetyl-D-cysteine 具有抗氧化活性，通过与巯基反应清除 ROS，但不能进入谷胱甘肽代谢途径。 | |||
| M14342
|
DL-Homocysteine | DL-同型半胱氨酸；DL-高半胱氨酸 | Metabolite/Endogenous Metabolite |
| DL-Homocysteine 是一种弱的神经毒素，可以影响犬尿酸的产生。同型半胱氨酸是一种含巯基的氨基酸，由甲硫氨酸合成。它是一种非必需的非蛋白原氨基酸。它是甲基化循环的重要决定因素，在血浆中有四种存在形式。 | |||
| M15006 | S-1-Propenyl-L-cysteine | S-1-Propenyl-L-cysteine | Others |
| S-1-Propenyl-L-cysteine 是 S-allyl-l-cysteine 的立体异构体，存在于大蒜中，具有免疫调节作用；在高血压动物模型中，可降低低血压。 | |||
| M20502 | H-Cys(Trt)-OH | H-Cys(Trt)-OH | Others |
| L-Cys(Trt)-OH, H-L-Cys(Trt)-OH, S-Tritylcysteine | |||
| H-Cys(Trt)-OH is a specific inhibitor of Eg5 that inhibits Eg5-driven microtubule sliding velocity in a reversible fashion with an IC50 of 500 nM. | |||
| M20898
|
L-Cysteine HCl | L-半胱氨酸盐酸盐 | Metabolite/Endogenous Metabolite |
| L-Cysteine hydrochloride | |||
| L-Cysteine hydrochloride 是一种条件必需氨基酸，是硫化氢 (H2S)、谷胱甘肽和牛磺酸等生物活性分子的前体。L-Cysteine hydrochloride 能抑制胃饥饿素。L-Cysteine Hydrochloride 被归类为半胱氨酸或半胱氨酸衍生物，可提高谷胱甘肽水平，对肺、脑功能和肝脏解毒非常重要。 | |||
| M20953 | 2-Aminoethanethiol | 2-Aminoethanethiol | Others |
| cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine | |||
| 2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine. | |||
| M31114
|
L-Homocysteine thiolactone hydrochloride | L-同型半胱氨酸硫内酯盐酸盐 | Others |
| L-Homocysteine thiolactone hydrochloride 同型半胱氨酸硫代内酯是一种胺反应剂，被用于研究蛋白质翻译后修饰，尤其是赖氨酸残基的修饰。 | |||
| M39258 | N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine | N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine | Amino Acid Derivatives |
| N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine 是一种半胱氨酸衍生物。 | |||
| M42292 | Se-Methylselenocysteine hydrochloride | Se-Methylselenocysteine hydrochloride | BACE |
| Se-Methylselenocysteine hydrochloride，甲基硒的前体，具有强大的癌症化学预防活性和抗氧化活性。 | |||
| M43202 | Glycylglycylcysteine | Glycylglycylcysteine | Others |
| Glycylglycylcysteine 是一种凝血酶激活纤维蛋白溶解抑制物 (TAFI) 抑制剂，在 TAFI 底物测定中，其 Ki 为 0.99 μM，IC50 为 9.4 μM。 | |||
| M45193
|
L-Homocysteine | L-高半胱氨酸 | Metabolite/Endogenous Metabolite |
| L-Homocysteine是一种高半胱氨酸代谢物，是有 L 构型的高半胱氨酸。在高同型半胱氨酸血症中，L-Homocysteine 诱导的组织蛋白酶 V 上调能介导血管内皮炎症。 | |||
| M45203
|
γ-Glu-Cys | γ-谷氨酰半胱氨酸 | Metabolite/Endogenous Metabolite |
| Gamma-glutamylcysteine | |||
| γ-Glu-Cys是一种含有半胱氨酸和谷氨酸的二肽，同时也是谷胱甘肽 (GSH) 的前体。此外，γ-Glu-Cys还是谷胱甘肽过氧化物酶 (GPx) 增加 GSH 水平的辅助因子。 | |||
| M49676 | S-Propargylcysteine | S-Propargylcysteine | STAT |
| S-Propargylcysteine (SPRC) 是 S-烯丙基半胱氨酸 (SAC) 的结构类似物，是一种缓慢释放 H2S 的化合物。 | |||
| M51039 | Paracetamol-cysteine | Paracetamol-cysteine | Others |
| Paracetamol-cysteine 是扑热息痛-半胱氨酸扑热息痛蛋白加合物 (PPA)，当扑热息痛被氧化成反应性代谢物 n -乙酰基-对苯醌亚胺 (NAPQI) 时形成。 | |||
| M51312 | N-Butyryl-DL-homocysteine thiolactone | N-Butyryl-DL-homocysteine thiolactone | Others |
| N-Butyryl-DL-homocysteine thiolactone 是一种 N- 酰基高丝氨酸内酯 (AHL) 类似物。 | |||
| M51850 | S-(5′-Adenosyl)-L-cysteine | S-(5′-Adenosyl)-L-cysteine | Amino Acid Derivatives |
| S-(5′-Adenosyl)-L-cysteine 是一种半胱氨酸衍生物。 | |||
| M51915 | S-(Acetamidomethyl)-L-cysteine hydrochloride | S-(Acetamidomethyl)-L-cysteine hydrochloride | Amino Acid Derivatives |
| S-(Acetamidomethyl)-L-cysteine hydrochloride 是一种半胱氨酸衍生物。 | |||
| M51984 | N-Boc-S-benzyl-D-cysteine | N-Boc-S-benzyl-D-cysteine | Amino Acid Derivatives |
| N-Boc-S-benzyl-D-cysteine 是一种半胱氨酸衍生物。 | |||
| M51988 | S-tert-Butylmercapto-L-cysteine | S-tert-Butylmercapto-L-cysteine | Amino Acid Derivatives |
| S-tert-Butylmercapto-L-cysteine 是一种半胱氨酸衍生物。 | |||
| M52137 | S-tert-Butyl-L-cysteine hydrochloride | S-tert-Butyl-L-cysteine hydrochloride | Amino Acid Derivatives |
| S-tert-Butyl-L-cysteine hydrochloride 是一种半胱氨酸衍生物。 | |||
| M52144 | N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(4-(tert-butoxy)-4-oxobutyl)-L-cysteine | N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(4-(tert-butoxy)-4-oxobutyl)-L-cysteine | Amino Acid Derivatives |
| N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(4-(tert-butoxy)-4-oxobutyl)-L-cysteine 是一种半胱氨酸衍生物。 | |||
| M52178 | S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine | S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine | Amino Acid Derivatives |
| S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine 是一种半胱氨酸衍生物。 | |||
| M2823
|
Loxistatin Acid(E-64C) | 阿洛司他丁酸 | Cathepsin |
| NSC 694279, EP 475 | |||
| Loxistatin Acid (E-64C), E-64的衍生物, 是一种不可逆的膜渗透性 cysteine protease 抑制剂。 | |||
| M3865
|
L-Buthionine-sulfoximine | L-丁硫氨酸亚砜亚胺 | Ferroptosis |
| L-Buthionine-(S,R)-sulfoximine; BSO | |||
| L-Buthionine-sulfoximine（L-丁硫氨酸亚砜亚胺）是一种具有细胞渗透性的、有效的、快速起效的、不可逆的 G-谷氨酸半胱氨酸合成酶 (γ-glutamylcysteine synthetase) 抑制剂，可消耗内源性细胞铜螯合剂谷胱甘肽，使细胞对Elesclomol-copper诱导的细胞死亡敏感。L-Buthionine-sulfoximine也是一种铁死亡（ferroptosis）诱导剂。 | |||
| M54564
|
Recombinant Mouse/Rat TGF-beta 2 Protein (Mammalian) | 重组Mouse/Rat TGF-beta 2 Protein (Mammalian) | Recombinant Proteins |
| TGFB2; TGFβ2; transforming growth factor beta-2 | |||
| Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. | |||
| M7804 | 5-Fluoro-2′-deoxycytidine | 5-Fluoro-2′-deoxycytidine | Others |
| 5-Fluoro-2′-deoxycytidine is a mechanism based DNMT (DNA cytosine-5 methyltransferase) inhibitor, that forms a covalent link with the cysteine residue in the active site of DNMT. | |||
| M8767 | MIND4-17 | MIND4-17 | Others |
| MIND4-17 is a potent NRF2 (nuclear factor erythroid 2-related factor 2) activator that covalently modifies a critical stress-sensor cysteine (C151) in the BTB domain of the E3 ligase substrate adaptor protein Kelch-like ECH-associated protein 1 (KEAP1). | |||
| M11185 | 3-Deazaadenosine hydrochloride | 3-脱氮腺苷盐酸盐 | Others |
| 3-DZA HCl, c3Ado HCl | |||
| 3-Deazaadenosine HCl (3-DZA, c3Ado)是一种有效的 S-adenosylhomocysteine hydrolase 的抑制剂，Ki值为3.9 μM。3-Deazaadenosine HCl 可抑制细菌脂多糖诱导的 TNF-α 和 IL-1β 的转录。3-Deazaadenosine HCl 可抑制 NF-κB 的转录活性，阻止FCS诱导的 Ras 的羧基甲基化，并降低FCS诱导的 ERK1/2 和 Akt 磷酸化。 | |||
| M13545
|
DL-Buthionine-(S,R)-sulfoximine | DL-Buthionine-(S,R)-sulfoximine | Ferroptosis |
| Buthionine sulfoximine; BSO | |||
| DL-Buthionine-(S,R)-sulfoximine 是谷氨酰半胱氨酸合成酶生物合成 (glutamylcysteine synthetase biosynthesis) 的有效抑制剂。 | |||
| M14306
|
Cysteine Protease inhibitor hydrochloride | 半胱氨酸蛋白酶抑制剂 (盐酸盐) | Cathepsin |
| Cysteine Protease inhibitor hydrochloride是半胱氨酸蛋白酶(cysteine protease)抑制剂。 | |||
| M14309 | Z-LVG-CHN2 | Z-LVG-CHN2 | Cathepsin |
| Z-LVG-CHN2 是一种细胞内不可逆的半胱氨酸蛋白酶 (cysteine proteinase) 抑制剂。Z-LVG-CHN2 是一种三肽衍生物，模拟人半胱氨酸蛋白酶结合中心的一部分。Z-LVG-CHN2 对 HSV 有抑制作用，但对脊髓灰质炎病毒复制无显著影响。通过抑制 SARS-COV-2 的 3CL pro 蛋白酶，Z-LVG-CHN2 有效地抑制 SARS-COV-2 活性 (EC50=190 nM)。 | |||
| M20806 | EN4 | EN4 | Others |
| EN4, a covalent ligand that targets cysteine 171 (C171) of MYC, is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis. | |||
| M20842 | C-171 | C-171 | STING |
| C-171 is a covalent small-molecule inhibitor of STING. C-171 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING. | |||
| M20860 | Eptifibatide Acetate | Eptifibatide Acetate | Others |
| Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 | |||
| Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes. | |||
| M21400 | LHVS | LHVS | Cathepsin |
| LHVS 是一种有效的，非选择性的，不可逆的，可透过细胞的半胱氨酸蛋白酶 (cysteine protease) 和组织蛋白酶 (cathepsin) 抑制剂。LHVS 可减少肌动蛋白环的形成。LHVS 抑制 T. gondii 侵袭，其 IC50 为 10 μM。 | |||
| M30931 | IA-Alkyne | IA-Alkyne | TRP Channel |
| Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide | |||
| IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) 是一种 TRP 通道 (TRPC) 的激动剂，有潜力用于呼吸道感染相关疾病的研究。IA-Alkyne 可以用来开发同位素标记的探针，用于定量的半胱氨酸反应分析 (cysteine-reactivity)。 | |||
| M31178
|
Recombinant Human Beta-NGF Protein (E. coli) | 重组人Beta-NGF蛋白 (E. coli) | Recombinant Proteins |
| β-NGF; NGFB; Beta-Nerve Growth Factor | |||
| Human β-Nerve Growth Factor (β-NGF) is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. | |||
| M42828 | L-Cystine hydrochloride | L-Cystine hydrochloride | Others |
| L-Cystine hydrochloride 是一种氨基酸，L-Cystine 可以在体内转化为 L-Cysteine。 | |||
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