找到约 30 条 “Histamine Receptor” 相关结果 （用时 0.1 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M25486
|
(S)-(+)-Dimethindene maleate | (S)-(+)-Dimethindene maleate | AChR/AChE |
| (S)-(+)-Dimethindene maleate 是一种有效的选择性毒蕈碱 M2 受体拮抗剂 (pA2 = 7.86/7.74; pKi = 7.78)。(S)-(+)-Dimethindene maleate 也是一种组胺 H1 受体 (histamine H1 receptor) 拮抗剂 (pA2 = 7.48)。 | |||
| M2639
|
Dimaprit dihydrochloride | Dimaprit dihydrochloride | Histamine Receptor |
| Dimaprit is a histamine type 2 receptor agonist. | |||
| M2643
|
Diphenylpyraline hydrochloride | 盐酸二苯比拉林；双苯比拉林盐酸盐 | Histamine Receptor |
| 4-Diphenylmethoxy-1-methylpiperidine hydrochloride | |||
| Diphenylpyraline hydrochloride (DPP) is an internationally available antihistamine that produces therapeutic antiallergic effects by binding to histamine H₁ receptors. | |||
| M2671
|
Epinastine hydrochloride | 依匹斯汀盐酸盐 | Histamine Receptor |
| WAL801 hydrochloride | |||
| Epinastine HCl是一种抗组胺剂和肥大细胞稳定剂。Epinastine hydrochloride 是一种有效的，选择性的，具有口服活性的组胺 H1 受体 (histamine H1 receptor) 拮抗剂。 | |||
| M2784
|
JNJ-7777120 | JNJ-7777120 | Histamine Receptor |
| JNJ-7777120是第一个，有效的，选择性非咪唑histamine H4 receptor拮抗剂，Ki为4.5 nM，比作用于其他组胺受体选择性高1000倍以上。 | |||
| M5752
|
Loratadine | 氯雷他定 | Histamine Receptor |
| SCH29851 | |||
| Loratadine是一种选择性的histamine H1 receptor拮抗剂，用于治疗过敏。同时还是一种选择性的B(0)AT2抑制剂，其IC50为 4 μM。 | |||
| M5921
|
Ranitidine hydrochloride | 盐酸雷尼替丁 | Histamine Receptor |
| AH19065 Hydrochloride | |||
| Ranitidine hydrochloride 是一种有效的，选择性的，具有口服活性的组胺 H2 受体 (histamine H2-receptor) 拮抗剂，IC50 为 3.3 μM。 | |||
| M7722 | Ciproxifan hydrochloride | 环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯基]甲酮盐酸盐 | Others |
| Ciproxifan（CPX） belongs to a novel chemical series of histamine H3-receptor antagonists. | |||
| M7849 | Imetit dihydrobromide | Imetit dihydrobromide | Others |
| Potent and selective H3 histamine receptor agonist. | |||
| M7856 | Immepip dihydrobromide | Immepip dihydrobromide | Others |
| Immepip is a H3 and H4 histamine receptor agonist. | |||
| M7888 | Levocabastine hydrochloride | 左旋多巴 | Others |
| Non-peptide histamine H1 receptor antagonist; neurotensin NTS2 receptor ligand. | |||
| M8229 | Conessine | 地麻素；康丝碱；可内新；抗痢夹竹桃碱；锥丝碱；止泻木碱 | Others |
| Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors (Ki = 5. | |||
| M8795 | Thioperamide maleate salt | Thioperamide maleate salt | Others |
| Potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier. | |||
| M8821
|
Triprolidine hydrochloride | 盐酸曲普利啶 | Others |
| H1 histamine receptor antagonist. | |||
| M9172
|
Emedastine Difumarate | 富马酸依美斯汀 | Histamine Receptor |
| Rapimine | |||
| Emedastine Difumarate is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. | |||
| M9290
|
S 38093 | S 38093 | Histamine Receptor |
| S38093 | |||
| S 38093是一种组胺H3受体（histamine H3 receptors）的反向激动剂，对大鼠，小鼠和人H3受体显示出中等亲和力，Ki值分别为8.8，1.44和1.2 μM。 | |||
| M11287 | JNJ-39758979 | JNJ-39758979 | Histamine Receptor |
| JNJ-39758979是一种选择性的、具有口服活性的、高亲和力的组胺 H4 受体 (histamine H4 receptor) 拮抗剂，对人，小鼠，猴子的组胺 H4 受体的 Ki 值分别为 12.5、5.3 和 25 nM。JNJ-39758979 对组胺诱导的 cAMP 抑制作用具有拮抗作用，pA2 为 7.9。JNJ-39758979 具有良好的抗炎、止痒作用。 | |||
| M13991 | Bepotastine | 贝他斯汀；贝托司汀；贝托斯汀；贝他司汀 | Histamine Receptor |
| Bepotastine 是一种选择性的具有口服活性的第二代组胺 H1 受体 (histamine H1 receptor) 拮抗剂。Bepotastine 可用于过敏性鼻炎，过敏性结膜炎和荨麻疹/瘙痒症的研究。 | |||
| M20424 | CarbinoxaMine Maleate | CarbinoxaMine Maleate | Histamine Receptor |
| Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties. | |||
| M20511 | Betahistine | Betahistine | Histamine Receptor |
| Betahistine Dihydrochloride is a histamine H3 receptors inhibitor used as an antivertigo drug. | |||
| M20513
|
Hydroxyzine pamoate | Hydroxyzine pamoate | Others |
| Hydroxyzine pamoate, a derivative of hydroxyzine, is a histamine H1-receptor antagonist that has been used as anxiolytic and antihistaminic so that it is probably effective in the treatment of insomnia and withdrawal treatment. | |||
| M20515 | Emedastine | Emedastine | Histamine Receptor |
| Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM). | |||
| M20518 | Orphenadrine Hydrochloride | Orphenadrine Hydrochloride | Others |
| A muscarinic receptor antagonist, specifically an H1 histamine receptor antagonist. This compound is a muscle relaxant. Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel. | |||
| M20520 | Chloropyramine hydrochloride | Chloropyramine hydrochloride | Histamine Receptor |
| Halopyramine hydrochloride | |||
| Chloropyramine hydrochloride is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects. | |||
| M20782 | Pimethixene maleate | Pimethixene maleate | 5-HT Receptor |
| Pimetixene maleate | |||
| Pimethixene (Pimetixene) maleate is a highly potent antagonist of a broad range of monoamine receptors, inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2. | |||
| M20813 | Cyclizine | Cyclizine | Histamine Receptor |
| Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor. | |||
| M20927 | Betahistine mesylate | Betahistine mesylate | Histamine Receptor |
| Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator. | |||
| M20988 | Promethazine | Promethazine | Histamine Receptor |
| Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties. | |||
| M20991 | Levocetirizine | Levocetirizine | Histamine Receptor |
| LCZ, (R)-Cetirizine | |||
| Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor. | |||
| M27613 | Irdabisant hydrochloride | Irdabisant hydrochloride | Histamine Receptor |
| CEP-26401 hydrochloride | |||
| Irdabisant (CEP-26401) hydrochloride 是一种具有选择性、口服活性和血脑屏障渗透性的组胺 H3 受体 (histamine H3 receptor, H3R) 拮抗剂/逆激动剂，对大鼠 H3R 和人 H3R 的 Ki 分别为 7.2 nM 和 2.0 nM。Irdabisant hydrochloride 对 hERG 电流的抑制活性相对较低，IC50 为 13.8 μM。 | |||
