M2225
|
Thalidomide |
Thalidomide（沙利度胺）是一种 cereblon (cullin-4 E3 泛素连接酶复合物 CUL4-RBX1-DDB1 的一部分)抑制剂，Kd 值约为 250 nM。具有免疫调节，抗炎和抗肿瘤活性，可用于许多癌症的相关研究。 |
| M43894
|
3-[[4-[[4-(Methylamino)-1-piperidinyl]methyl]phenyl]amino]-2,6-piperidinedione |
3-[[4-[[4-(Methylamino)-1-piperidinyl]methyl]phenyl]amino]-2,6-piperidinedione |
| M43893
|
Dihydro-1-[6-[4-(hydroxymethyl)-1-piperidinyl]-3-pyridinyl]-2,4(1H,3H)-pyrimidinedione |
Dihydro-1-[6-[4-(hydroxymethyl)-1-piperidinyl]-3-pyridinyl]-2,4(1H,3H)-pyrimidinedione |
| M43892
|
3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-fluorobenzoic acid |
3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-fluorobenzoic acid |
| M43889
|
2,4(1H,3H)-Pyrimidinedione, dihydro-1-(1,2,3,4-tetrahydro-6-isoquinolinyl)-, hydrochloride |
2,4(1H,3H)-Pyrimidinedione, dihydro-1-(1,2,3,4-tetrahydro-6-isoquinolinyl)-, hydrochloride |
| M43887
|
1-(5-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)pyridin-2-yl)piperidine-4-carbaldehyde |
1-(5-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)pyridin-2-yl)piperidine-4-carbaldehyde |
| M43884
|
1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-4-piperidinecarboxylic acid |
1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-4-piperidinecarboxylic acid |
| M43883
|
3-[1-methyl-6-(4-piperidyl)indazol-3-yl]piperidine-2,6-dione |
3-[1-methyl-6-(4-piperidyl)indazol-3-yl]piperidine-2,6-dione |
| M43882
|
1-(4-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)phenyl)piperidine-4-carbaldehyde |
1-(4-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)phenyl)piperidine-4-carbaldehyde |
| M43881
|
1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-3-pyrrolidinecarboxaldehyde |
1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-3-pyrrolidinecarboxaldehyde |
| M43877
|
3-[[4-[4-(Methylamino)-1-piperidinyl]phenyl]amino]-2,6-piperidinedione |
3-[[4-[4-(Methylamino)-1-piperidinyl]phenyl]amino]-2,6-piperidinedione |
| M43876
|
1,1-Dimethylethyl 6-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate |
1,1-Dimethylethyl 6-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate |
| M43875
|
2(1H)-Isoquinolineacetic acid, 6-(2,6-dioxo-3-piperidinyl)-3,4-dihydro- |
2(1H)-Isoquinolineacetic acid, 6-(2,6-dioxo-3-piperidinyl)-3,4-dihydro- |
| M43874
|
4-[3-(2,6-Dioxo-3-piperidinyl)-1-methyl-1H-indazol-6-yl]-3,3-difluoro-1-piperidineacetic acid |
4-[3-(2,6-Dioxo-3-piperidinyl)-1-methyl-1H-indazol-6-yl]-3,3-difluoro-1-piperidineacetic acid |
| M43873
|
2,6-Piperidinedione, 3-[2,3-dihydro-3-methyl-2-oxo-5-(4-piperidinyl)-1H-benzimidazol-1-yl]- |
2,6-Piperidinedione, 3-[2,3-dihydro-3-methyl-2-oxo-5-(4-piperidinyl)-1H-benzimidazol-1-yl]- |
| M43872
|
4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]- |
4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]- |
| M43871
|
3-[6-(2,7-Diazaspiro[3.5]non-7-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione |
3-[6-(2,7-Diazaspiro[3.5]non-7-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione |
| M43870
|
3-[6-(2,6-Diazaspiro[3.3]hept-2-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione |
3-[6-(2,6-Diazaspiro[3.3]hept-2-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione |
| M43868
|
3-[6-(4-Amino-1-piperidinyl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione |
3-[6-(4-Amino-1-piperidinyl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione |
| M43865
|
Cyclohexanecarboxaldehyde, 4-[[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]oxy]-, trans- |
Cyclohexanecarboxaldehyde, 4-[[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]oxy]-, trans- |
| M43864
|
4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- |
4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- |
