人源化单克隆抗体
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M55669
|
Anti-Mouse IFNß (interferon beta) Antibody (Clone HDß-4A7) In vivo | Anti-Mouse IFNß (interferon beta) Antibody (Clone HDß-4A7) In vivo | Interferon-α/β/γ |
| IFN-b, IFN-beta, Type-1 interferon | |||
| Anti-Mouse Interferon-beta (IFN-ß) (Clone HDß-4A7) recognizes an epitope on Mouse IFN-ß and binds specifically to murine IFNß and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms. | |||
| M55206
|
Lintuzumab | 林妥珠单抗 | Immunology/Inflammation |
| Lintuzumab 是一种针对 CD33 的人源化单克隆抗体，急性髓性白血病的大多数髓母细胞都表达 CD33。 | |||
| M54716
|
Trontinemab | Trontinemab | Amyloid |
| RG6102; RO-7126209 | |||
| Trontinemab 是一种双特异性人源 IgG1-κ 抗体，能靶向淀粉样蛋白 β A4 前体蛋白 (APP) 和转铁蛋白受体 (TFRC)。Trontinemab 可用于阿兹海默症的相关研究。 | |||
| M54551
|
Rademikibart | Rademikibart | IL Receptor/Related |
| CBP-201 | |||
| Rademikibart是一种人 IgG4ҡ 单克隆抗体，可靶向 IL-4 Rα 阻断由 IL-4 和 IL-13 这两种驱动过敏性炎症的重要细胞因子引起的炎症信号转导，与人 IL-4Rα 表位结合时的 KD 为 20.7 pM。Rademikibart 不与其他物种的 IL-4Rα 结合。Rademikibart 能抑制 PBMC 中 IL-4 和 IL-13 介导的 STAT6 信号传导、TF-1 细胞增殖和 TARC 产生，可用于中重度 Th2 炎症性疾病的相关研究。 | |||
| M54547
|
Enlonstobart | Enlonstobart | Others |
| Enlonstobart是一种重组人源化抗 PD-1 IgG4ҡ 单克隆抗体，可用于肿瘤的相关研究。 | |||
| M49822
|
ANX005 | ANX005 | Complement System |
| ANX005是一种单克隆抗体，能通过抑制处于补体级联反应上游补体蛋白C1q，从而阻断整个经典信号通路的激活，同时还能保持其它补体途径功能的完整性。可用于格林-巴利综合征（GBS）的相关研究。 | |||
| M45360
|
LYT-200 | LYT-200 | Galectin |
| Anti-Human LGALS9 | |||
| Research Grade Anti-Human LGALS9 (LYT-200) 是一种靶向半乳糖凝集素-9（galectin-9）的单克隆抗体，并具有抗肿瘤活性。 | |||
| M40939
|
Rat IgG2b Isotype Control In vivo | Rat IgG2b Isotype Control In vivo | Others |
| Rat IgG2b Isotype Control In vivo 单克隆抗体（克隆号：1-2）可与锁孔血蓝蛋白 (keyhole limpet hemocyanin, KLH) 发生反应。由于哺乳动物不表达 KLH，因此该抗体非常适合在大多数体内和体外应用中用作大鼠 IgG2b 抗体的同种型匹配对照。 | |||
| M40936
|
Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo | Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo | GPR/FFAR |
| Anti-Mouse CD4 Antibody (克隆号：GK1.5) 克隆抗体可与小鼠CD4结合反应。CD4是T细胞受体（TCR）的协同受体，有助于后续与抗原呈递细胞的交流通讯。 | |||
| M40935
|
Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo | Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo | Interferon-α/β/γ |
| Interferon Gamma | |||
| Anti-Mouse IFNγ (Clone H22)单克隆抗体与小鼠IFNγ(interferon gamma)反应。IFNγ是一种20 kDa的可溶性多效性细胞因子，是II型干扰素的唯一成员。 | |||
| M40934
|
Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo | Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo | Immunology/Inflammation |
| Cytotoxic T Lymphocyte-Associated Antigen-4 | |||
| Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes. | |||
| M40918
|
Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo | Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo | Immunology/Inflammation |
| Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils. | |||
| M40909
|
Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo | Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo | Immunology/Inflammation |
| Lyt2, Ly-2 | |||
| Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo recognizes Lyt 2. Clone 53-6.7 competes with clone 5H10-1 for binding to thymocytes. | |||
| M40875
|
Brazikumab | 布雷库单抗 | IL Receptor/Related |
| AMG 139; MEDI2070 | |||
| Brazikumab 是一种靶向IL-23的人 IgG2 单克隆抗体，可选择性结合 IL-23 的 p19 亚基，对人 IL-23 的 KD 值为 0.138 nM，可用于克罗恩病（CD）的研究。 | |||
| M40856
|
Anti-Mouse CD4 Antibody (Clone YTS191) In vivo | Anti-Mouse CD4 Antibody (Clone YTS191) In vivo | GPR/FFAR |
| Anti-Mouse CD4 Antibody (Clone YTS191) In vivo 可与小鼠CD4结合反应。CD4是T细胞受体（TCR）的协同受体，有助于后续与抗原呈递细胞的交流通讯。 | |||
| M40830
|
Anti-Mouse CD3ε Antibody In vivo | Anti-Mouse CD3ε Antibody In vivo | Immunology/Inflammation |
| Anti-Mouse CD3Epsilon | |||
| Anti-Mouse CD3ε Antibody (Clone 145-2C11) In vivo单克隆抗体与小鼠CD3ε反应。小鼠CD3ε是一种20 kDa的跨膜细胞表面蛋白，属于免疫球蛋白超家族。 | |||
| M40828
|
Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo | Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo | Immunology/Inflammation |
| Cytotoxic T Lymphocyte-Associated Antigen-4 | |||
| 抗鼠CTLA-4抗体（克隆9H10）识别小鼠CTLA-4上的表位。CTLA-4在活化的T和B淋巴细胞上表达。 | |||
| M40812
|
Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo | Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo | Immunology/Inflammation |
| Anti-Mouse GR-1 | |||
| Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo. | |||
| M40806
|
Anti-Mouse NK1.1 Antibody In vivo | Anti-Mouse NK1.1 Antibody In vivo | Others |
| This NK1.1 antibody (clone PK136) recognizes mouse NK1.1. NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. | |||
| M40797
|
Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo | Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo | Interferon-α/β/γ |
| IFNG | |||
| Anti-Mouse IFNγ Antibody 单克隆抗体与小鼠 IFNγ (interferon gamma) 反应。IFNγ是一种20 kDa的可溶性多效性细胞因子，是II型干扰素的唯一成员。 | |||
关键词：人源化单抗, 抗体抑制剂, 治疗性抗体, 全人源化单克隆抗体, humanized monoclonal antibody
