人源化单克隆抗体
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M49822
|
ANX005 | ANX005 | Complement System |
| ANX005是一种单克隆抗体，能通过抑制处于补体级联反应上游补体蛋白C1q，从而阻断整个经典信号通路的激活，同时还能保持其它补体途径功能的完整性。可用于格林-巴利综合征（GBS）的相关研究。 | |||
| M45360
|
LYT-200 | LYT-200 | Galectin |
| Anti-Human LGALS9 | |||
| Research Grade Anti-Human LGALS9 (LYT-200) 是一种靶向半乳糖凝集素-9（galectin-9）的单克隆抗体，并具有抗肿瘤活性。 | |||
| M40939
|
Rat IgG2b Isotype Control In vivo | Rat IgG2b Isotype Control In vivo | Others |
| Rat IgG2b Isotype Control In vivo 单克隆抗体（克隆号：1-2）可与锁孔血蓝蛋白 (keyhole limpet hemocyanin, KLH) 发生反应。由于哺乳动物不表达 KLH，因此该抗体非常适合在大多数体内和体外应用中用作大鼠 IgG2b 抗体的同种型匹配对照。 | |||
| M40936
|
Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo | Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo | GPR/FFAR |
| Anti-Mouse CD4 Antibody (克隆号：GK1.5) 克隆抗体可与小鼠CD4结合反应。CD4是T细胞受体（TCR）的协同受体，有助于后续与抗原呈递细胞的交流通讯。 | |||
| M40935
|
Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo | Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo | Interferon-α/β/γ |
| Interferon Gamma | |||
| Anti-Mouse IFNγ (Clone H22)单克隆抗体与小鼠IFNγ(interferon gamma)反应。IFNγ是一种20 kDa的可溶性多效性细胞因子，是II型干扰素的唯一成员。 | |||
| M40934
|
Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo | Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo | Immunology/Inflammation |
| Cytotoxic T Lymphocyte-Associated Antigen-4 | |||
| Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes. | |||
| M40918
|
Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo | Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo | Immunology/Inflammation |
| Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils. | |||
| M40909
|
Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo | Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo | Immunology/Inflammation |
| Lyt2, Ly-2 | |||
| Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo recognizes Lyt 2. Clone 53-6.7 competes with clone 5H10-1 for binding to thymocytes. | |||
| M40875
|
Brazikumab | 布雷库单抗 | IL Receptor/Related |
| AMG 139; MEDI2070 | |||
| Brazikumab 是一种靶向IL-23的人 IgG2 单克隆抗体，可选择性结合 IL-23 的 p19 亚基，对人 IL-23 的 KD 值为 0.138 nM，可用于克罗恩病（CD）的研究。 | |||
| M40856
|
Anti-Mouse CD4 Antibody (Clone YTS191) In vivo | Anti-Mouse CD4 Antibody (Clone YTS191) In vivo | GPR/FFAR |
| Anti-Mouse CD4 Antibody (Clone YTS191) In vivo 可与小鼠CD4结合反应。CD4是T细胞受体（TCR）的协同受体，有助于后续与抗原呈递细胞的交流通讯。 | |||
| M40830
|
Anti-Mouse CD3ε Antibody In vivo | Anti-Mouse CD3ε Antibody In vivo | Immunology/Inflammation |
| Anti-Mouse CD3Epsilon | |||
| Anti-Mouse CD3ε Antibody (Clone 145-2C11) In vivo单克隆抗体与小鼠CD3ε反应。小鼠CD3ε是一种20 kDa的跨膜细胞表面蛋白，属于免疫球蛋白超家族。 | |||
| M40828
|
Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo | Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo | Immunology/Inflammation |
| Cytotoxic T Lymphocyte-Associated Antigen-4 | |||
| Anti-Mouse CTLA-4 Antibody (Clone 9H10) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes. | |||
| M40812
|
Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo | Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo | Immunology/Inflammation |
| Anti-Mouse GR-1 | |||
| Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo. | |||
| M40806
|
Anti-Mouse NK1.1 Antibody In vivo | Anti-Mouse NK1.1 Antibody In vivo | Others |
| This NK1.1 antibody (clone PK136) recognizes mouse NK1.1. NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. | |||
| M40797
|
Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo | Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo | Interferon-α/β/γ |
| IFNG | |||
| Anti-Mouse IFNγ Antibody 单克隆抗体与小鼠 IFNγ (interferon gamma) 反应。IFNγ是一种20 kDa的可溶性多效性细胞因子，是II型干扰素的唯一成员。 | |||
| M40795
|
Anti-Mouse IL-4 Antibody In vivo | Anti-Mouse IL-4 Antibody In vivo | IL Receptor/Related |
| Interleukin-4 | |||
| Anti-Mouse IL-4 Antibody In vivo单克隆抗体可与小鼠IL-4 (interleukin-4)反应。Anti-Mouse IL-4 In vivo单克隆抗体可中和天然或重组IL-4的生物活性。 | |||
| M40769
|
Anti-Mouse/Human TGF-β Antibody In vivo | Anti-Mouse/Human TGF-β Antibody In vivo | TGF-beta/Smad |
| Anti-Mouse/Human TGF-β1, 2, 3 | |||
| Anti-Mouse/Human TGF-β Antibody In vivo (Clone: 1D11.16.8) 单克隆抗体与小鼠，人类，大鼠，猴子，仓鼠，犬和牛的TGF-β1、2 和 3反应。该抗体是中和抗体。 | |||
| M40768
|
Anti-Mouse IFNAR-1 Antibody In vivo | Anti-Mouse IFNAR-1 Antibody In vivo | Interferon-α/β/γ |
| Anti-Mouse IFNAR-1 Antibody In vivo 单克隆抗体（Clone: MAR1-5A3）可与 mouse IFNAR-1 (IFN alpha/beta receptor subunit 1) 发生反应。Anti-Mouse IFNAR-1 In vivo 可在体外和体内抑制 I 型 IFN 受体信号传导。 | |||
| M40764
|
Anti-Mouse PD-L1 mAb In vivo | 重组小鼠PD-L1中和单抗 | PD-1/PD-L1 |
| B7-H1, CD274 | |||
| Anti-Mouse PD-L1 Antibody (Clone 10F.9G2) 单克隆抗体可与小鼠 PD-L1（也称为B7-H1、CD274）发生反应。10F.9G2 抗体已被证明可以阻断 PD-L1 和 PD-1 之间以及 PD-L1 和 B7-1 (CD80) 之间的相互作用。 | |||
| M40599
|
Ocrelizumab | 奥美珠单抗；奥瑞珠单抗；奥瑞利珠单抗 | CD20 |
| Ocrelizumab是一种人源化抗CD20单克隆抗体，可用于多发性硬化的相关研究。 | |||
关键词：人源化单抗, 抗体抑制剂, 治疗性抗体, 全人源化单克隆抗体, humanized monoclonal antibody
