找到约 11 条 “Receptor Proteins” 相关结果 (用时 0.133 秒)

目录号 产品名称 中文名称 靶点
M8774 CID 1375606 CID 1375606 Others
CID1375606
CID 1375606 (N-[4-(Anilinocarbonyl)phenyl]-2,4-dichlorobenzamide) is a specific and potent surrogate agonist of GPR27 (SREB1) that induces coupling of the receptor to β-arrestin 2 but not to G proteins.
M15008 Recombinant Human Carboxypeptidase E/CPE (HEK293,C-6His) 重组人Carboxypeptidase E/CPE蛋白(HEK293,C-6His) Cytokines and Growth Factors
Carboxypeptidase H; Enkephalin convertase
CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway.
M21203 Recombinant Human/Mouse/Rat Irisin (HEK293, C-6His) 重组人/小鼠/大鼠Irisin蛋白 (HEK293, C-6His) Cytokines and Growth Factors
Fibronectin type III domain-containing protein 5
Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.
M21204 Recombinant Human/Mouse/Rat Irisin (HEK293, C-Fc) 重组人/小鼠/大鼠Irisin蛋白 (HEK293, C-Fc) Cytokines and Growth Factors
Fibronectin type III domain-containing protein 5
Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.
M21205 Recombinant Human/Mouse/Rat Irisin (HEK293, N-6His) 重组人/小鼠/大鼠Irisin 蛋白(HEK293, N-6His) Cytokines and Growth Factors
Fibronectin type III domain-containing protein 5
Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.
M55355 Recombinant Mouse IGF-1 (E.coli, C-6His) 重组小鼠Recombinant Mouse IGF-1 (E.coli, C-6His) Cytokines and Growth Factors
Insulin-like Growth Factor I; LR3-IGF-1; Somatomedin C
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.
M55621 Recombinant Human ACVR2A Protein (HEK293, C-6His) 重组人ACVR2A 蛋白 (HEK293, C-6His) Cytokines and Growth Factors
Activin Receptor Type-2A; ACTR-IIA; ACVR2
Activin Receptor Type-2A (ACVR2A) is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.
M55622 Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His) 重组人BMPRIA/ALK-3/CD292 蛋白 (HEK293, C-His) Cytokines and Growth Factors
Bone Morphogenetic Protein Receptor type IA; Activin receptor-Like Kinase 3; ACVRLK3
BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-β) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion.
M58101 Recombinant Human EGFR Protein (CHO, C-His) 重组人EGFR 蛋白 (CHO, C-His) Cytokines and Growth Factors
ERBB; ERBB1; HER1; Epidermal Growth Factor Receptor
EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling.
M58892 Recombinant Human RAP (E.coli) 重组人RAP (E.coli) Target Proteins
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
M58893 Recombinant Human RAP (HEK293) 重组人RAP (HEK293) Target Proteins
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.








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