找到约 14 条 “Kinesin” 相关结果 （用时 0.108 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M1786
|
Ispinesib | 伊斯平斯；伊匹尼塞 | Kinesin |
| SB-715992, CK0238273 | |||
| Ispinesib (SB-715992)是一种有效的，特异性的，可逆的kinesin spindle protein (KSP)（纺锤体驱动蛋白）抑制剂，Kiapp为1.7 nM，对CENP-E， RabK6， MCAK， MKLP1， KHC和Kif1A没有抑制作用。 | |||
M1983
|
SB-743921 | SB-743921 | Kinesin |
| SB743921是一种kinesin spindle protein (KSP)（纺锤体驱动蛋白）抑制剂，Ki为0.1 nM，对MKLP1， Kin2， Kif1A， Kif15， KHC， Kif4和CENP-E几乎没有亲和力。 | |||
| M2128
|
AZ3146 | AZ3146 | Kinesin |
| AZ 3146 | |||
| AZ 3146是一种选择性Mps1抑制剂，IC50为35 nM左右，有助于招募CENP-E(kinesin相关的动力蛋白)，对FAK， JNK1， JNK2和Kit作用效果稍弱。此外，AZ3146 还是TTK的抑制剂。 | |||
| M2171
|
GSK923295 | GSK923295 | Kinesin |
| GSK923295是一级特异性变构抑制剂CENP-E(kinesin相关的动力蛋白)ATPase的变构抑制剂，Ki为3.2 nM，对突变型I182和T183作用效果稍弱。 | |||
| M5230
|
Monastrol | Monastrol | Kinesin |
| CAS# 254753-54-3 | |||
| Monastrol是一种具有细胞透性的kinesin-5(KIF11)小分子抑制剂，kinesin-5(KIF11)可保持半纺锤体的分离状态。 | |||
| M6674
|
Dimethylenastron | Dimethylenastron | Kinesin |
| Dimethylenastron is a inhibitor of mitotic motor kinesin Eg5. | |||
| M7876
|
K-858 | K-858 | Kinesin |
| K858 Racemic | |||
| K858 (Racemic) 是一种 ATP 非竞争性的驱动蛋白 Eg5 抑制剂，IC50 值为 1.3 μM。Eg5是一种有丝分裂驱动蛋白（kinesin），在建立有丝分裂纺锤体双极性中起重要作用。 | |||
| M8930
|
EMD534085 | EMD534085 | Kinesin |
| EMD534085是一种选择性的有丝分裂驱动蛋白-5 (kinesin-5) 抑制剂，IC50值为8 nM。 | |||
| M22468
|
Sovilnesib (AMG 650) | 索维奈西布；绍伊纳西布；绍维西布 | Microtubule |
| AMG 650 | |||
| Sovilnesib (AMG 650) 是一种口服有效的 kinesin-like protein KIF18A 抑制剂，其 IC50 值为 0.071 μM。 | |||
| M55997 | AZD4877 | AZD4877 | Kinesin |
| AZD4877是 Ispinesib 的另一种构型，是纺锤体驱动蛋白 (kinesin) (Eg5) 抑制剂，对其 IC50 值为 2 nM。 AZD4877 能够阻止细胞有丝分裂，并导致形成单极纺锤体表型，介导细胞凋亡(Apoptosis)。 | |||
| M58902
|
Recombinant Human KIF18A (BV) | 重组人KIF18A (BV) | Target Proteins |
| Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. | |||
| M58903
|
Recombinant Human KIF18A (E.coli) | 重组人KIF18A (E.coli) | Target Proteins |
| Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. | |||
| M58904
|
Recombinant Human KIF22 (E.coli) | 重组人KIF22 (E.coli) | Target Proteins |
| Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. | |||
| M58905
|
Recombinant Human KIF22 (BV) | 重组人KIF22 (BV) | Target Proteins |
| Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. | |||
