找到约 12 条 “Enzyme-IN-1” 相关结果 （用时 0.114 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M42587 | Enzyme-IN-1 | Enzyme-IN-1 | Proteasome |
| Enzyme-IN-1 是一种基于肽的 N 端亲核试剂 (Ntn) 水解酶抑制剂。 | |||
M4951
|
d-Alaninol | D-氨基丙醇 | Others |
| Coenzyme B(12)-dependent ethanolamine ammonia-lyase acts on both enantiomers of the substrate 2-amino-1-propanol. | |||
| M8414
|
MJN110 | MJN110 | MAGL |
| MJN110 is a potent selective inhibitor of MAGL, the enzyme predominantly responsible for the degradation of the endocannabinoid 2-arachidonoylglycerol (2-AG) with >10,000 selectivity over FAAH. | |||
| M8773 | Liarozole dihydrochloride | Liarozole dihydrochloride | Others |
| Liarozole (R 75251, R75,251) is an orally active benzimidazole-based retinoic acid (RA) metabolism blocking agent (RAMBA) that targets multiple P450 enzymes, including aromatase (CYP19), 17-hydroxylase/17,20-lyas |
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| M15018
|
Recombinant Human ACE-2 (HEK293,C-6His) | 重组人ACE-2蛋白 (HEK293,C-6His) | Cytokines and Growth Factors |
| Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase | |||
| 血管紧张素转换酶 2 (Angiotensin-Converting Enzyme 2, ACE-2) 是一种整合的膜蛋白和 ACE 家族的锌金属蛋白酶，ACE-2 将血管紧张素 I 和 II 切割为羧肽酶，ACE-2 将血管紧张素 I 转化为血管紧张素 1-9，将血管紧张素 II 转化为血管紧张素 1-7。ACE-2 还能够高效水解 apelin-13 和 dynorphin-13。 | |||
| M19993
|
Recombinant Human B4GALT1 (HEK293, C-6His) | 重组人B4GALT1 蛋白(HEK293, C-6His) | Cytokines and Growth Factors |
| 1,4- galactosyltransferase, polypeptide 1; B4GalT1 | |||
| Beta1,4-Galactosyltransferase-I (B4GALT1) is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. Accession: P15291. | |||
| M20575 | Lucanthone | Lucanthone | Autophagy |
| Lucanthone is a novel autophagic inhibitor and also an orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme apurinic-apyrimidinic endonuclease 1. | |||
| M20652 | JNJ-38877618 | JNJ-38877618 | c-Met |
| JNJ-38877618 (OMO-1) is a potent, highly selective, orally bioavailable MET kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant MET (2 and 3 nM IC50). | |||
| M20771 | RP-64477 | RP-64477 | Others |
| RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively. | |||
| M21212
|
Recombinant Human Arylsulfatase A/ARSA (HEK293, C-6His) | 重组人Arylsulfatase A/ARSA蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA | |||
| Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, Recombinant Human Arylsulfatase A/ARSA expressed the target gene encoding Arg19-Ala507 with a 6His tag at the C-terminus. | |||
| M31127
|
Recombinant Human MMP-2 Protein (HEK293, C-6His) | 重组人MMP-2蛋白 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-2; Gelatinase A | |||
| Recombinant Human MMP-2 (also known as matrix metalloproteinase-2) is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. The proenzyme needs to be activated by APMA for an activated form. | |||
| M54866
|
Recombinant Human USP14 (E.coli, N-6His) | 重组人USP14 (E.coli, N-6His) | Cytokines and Growth Factors |
| Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14 | |||
| USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. | |||
