找到约 29 条 “Antifungal” 相关结果 (用时 0.112 秒)
目录号 | 产品名称 | 中文名称 | 靶点 |
---|---|---|---|
M3953 | Voriconazole | 伏立康唑 | Cytochrome P450 (e.g. CYP17) |
UK-109496 | |||
Voriconazole (UK-109496,伏立康唑) 是14α-羊毛甾醇脱甲基酶的抑制剂,IC50值为53nM。Voriconazole (UK-109496) 是广谱的三唑类抗真菌 (antifungal) 化合物,可抑制真菌麦角甾醇的生物合成。 | |||
M4879 | Cycloheximide | 放线菌酮 | DNA/RNA Synthesis |
Naramycin A; Actidione; CHX; FT 3422-2; NM-MCD 80 | |||
Cycloheximide是一种蛋白生物合成 (protein synthesis) 的抑制剂, IC50值为532.5 nM。Cycloheximide (Naramycin A) 也是一种抗真菌 (antifungal) 素,Cycloheximide 还可抑制铁死亡 (ferroptosis) 并抑制自噬 (autophagy)。 | |||
M7151 | Polygodial | 水蓼二醛 | Others |
Polygodial is a tRPA1 channel activator; analgesic and antifungal. | |||
M7893 | Leptomycin A | 来普霉素A | Others |
Leptomycins are antifungal antibiotics with unique unsaturated, branched-chain fatty acid structures. | |||
M8157 | Sordarin sodium salt | Sordarin sodium salt | Others |
Sordarin is an antifungal metabolite possessing a tetracyclic diterpene glycoside structure. | |||
M8588 | iKIX1 | iKIX1 | Others |
iKIX1 is an antifungal agent that can re-sensitize drug-resistant Candida glabrata to azole antifungals. | |||
M8592 | Brassinin | 芸苔宁 | Others |
Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. | |||
M8701 | Inz-1 | Inz-1 | Others |
Inz-1 is a potent and selective inhibitor of yeast mitochondrial cytochrome bc1 that reverses resistance to triazole antifungals in the pathogenic fungus Candida albicans. | |||
M9157 | 2-Phenylethyl isothiocyanate | 2-苯基乙基异硫代氰酸酯;异硫氰酸-2-苯基乙酯;异硫氰酸苯乙酯 | Antifungal |
Isothiocyanic Acid 2-Phenylethyl Ester;2-PE ITC; PEITC | |||
2-Phenylethyl isothiocyanate是一种存在于豆瓣菜和十字花科蔬菜中的天然产物,同时也是有效的抗真菌剂 (antifungal),能显著抑制互隔交链孢霉的孢子萌发和菌丝生长。此外,2-Phenylethyl isothiocyanate还能诱导自噬,同时抑制多种肿瘤细胞的生长。 | |||
M11173 | PC945 | PC945 | Others |
PC945 是一种有效的抗真菌 (antifungal) 三唑类药物,对多种敏感和耐药的烟曲霉菌株都具有抗药性。PC945 是烟曲霉甾醇 14α-去甲基酶 (CYP51A/CYP51B) 活性的有效、紧密结合的抑制剂,IC50s 分别为 0.23 μM 和 0.22 μM。 | |||
M11174 | Mefentrifluconazole | 氯氟醚菌唑 | Others |
Mefentrifluconazole 是一种新型的唑类衍生物,广谱抗真菌 (antifungal agent) 剂。Mefentrifluconazole 是具有强效选择性和口服活性真菌 CYP51 的抑制剂 (Kd= 0.5 nM)。 | |||
M17118 | Alternariol methyl ether | 交链孢酚单甲醚;交替烯醇甲醚 | Phenols |
Alternariol methyl ether exhibits antifungal and phytotoxic activity. Alternariol methyl ether is a cholinesterase inhibitor. | |||
M17299 | Xanthoxylin | 花椒油素;花椒素 | Phenols |
Xanthoxyline | |||
Xanthoxylin 花椒素具有抗真菌 (antifungal) 和抗癫痫活性。Xanthoxylin 是从 Zanthoxylum simulans 中分离出来的。 | |||
M19162 | Cauloside A | 葳岩仙皂苷A | Antifungal |
Cauloside A (Leontoside A) 是从 Dipsacus asper 根中分离出的皂苷。Cauloside A 具有有效的抗真菌 (antifungal) 活性。 | |||
M20471 | Suloctidil | Suloctidil | Others |
Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent. | |||
M20789 | Neticonazole | Neticonazole | Others |
SS717 | |||
Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity. | |||
M20895 | Chlorobutanol | Chlorobutanol | Anti-infection |
Chlorbutol, Chloreton, Chloretone, Chlortran| | |||
Chlorobutanol (trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties. | |||
M20918 | Butoconazole | Butoconazole | Anti-infection |
Butoconazole is an imidazole antifungal used in gynecology. | |||
M20946 | Butenafine | Butenafine | Anti-infection |
Butenafine is a synthetic benzylamine antifungal agent. | |||
M20959 | Fosfluconazole | Fosfluconazole | Anti-infection |
Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. | |||
M29194 | Fosmanogepix | Fosmanogepix | Antifungal |
APX001; E1211 | |||
Fosmanogepix (APX001) 是一种 N-磷酸氧基甲基前体化合物,能由全身碱性磷酸酶快速完全代谢为活性部分 APX001A,同时也是首创的(first-in-class)口服广谱抗真菌 (antifungal) 化合物,可靶向高度保守的 Gwt1 真菌酶。能用于侵袭性真菌感染的相关研究。 | |||
M30976 | Swinholide A | Swinholide A | Antifungal |
Swinholide A 是结合肌动蛋白的一种海洋聚酮化合物,可将肌动蛋白二聚化,Kd 约为 50 nM。Swinholide A 是一种破坏海洋毒素的微丝,可稳定肌动蛋白二聚体并切断肌动蛋白丝。Swinholide A 破坏细胞的肌动蛋白细胞骨架。具有抗真菌 (antifungal)活性。 | |||
M38719 | L-Diguluronic acid | L-Diguluronic acid | Antifungal |
L-Diguluronic acid 是一种由两个 L-guluronic acid (G) 组成的直链多糖共聚物,可用于海藻酸的合成。L-Diguluronic acid 是一种无支链聚阴离子多糖的总称,可用于抗真菌 (antifungal) 试剂的载体研究。 | |||
M38723 | Demethoxyencecalin | Demethoxyencecalin | Antifungal |
Demethoxyencecalin 是从一种从向日葵中提取的色烯,具有抗真菌 (antifungal) 活性。 | |||
M38731 | lsocryptomerin | lsocryptomerin | Antifungal |
lsocryptomerin 是一种具有膜活性的抗真菌 (antifungal) 化合物,可从Selaginella tamariscina 中分离得到。lsocryptomerin 能使真菌质膜去极化。 | |||
M38736 | 3-Oxobetulin | 3-Oxobetulin | Antifungal |
3-Oxobetulin 是一种抗真菌剂 (antifungal),对白腐真菌 L. betulina 和 褐腐真菌 L. sulphureus 都具有抗真菌活性。 | |||
M38742 | Eleutherol | 红葱酚 | Antifungal |
Eleutherol 是从 E. americana 中分离得到的萘类化合物,具有抗真菌 (antifungal) 活性。Eleutherol 抑制白假丝酵母菌,白色念珠菌,酿酒酵母和新型隐球菌的 MIC 值在 7.8-250 µg/mL 之间。 | |||
M53520 | Aminocandin | 氨基康定 | Antifungal |
Aminocandin (HMR 3270) 是一种水溶性的棘白菌素类抗真菌剂 (antifungal),对 Aspergillus 和 Candida spp. 具有良好的活性。 | |||
M53847 | Iturin A | Iturin A | Antifungal |
IturinA 对致病性酵母和真菌具有较强的抗真菌 (antifungal) 活性。 |
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