M1959
|
Oseltamivir |
Oseltamivir (Tamiflu)是一种竞争性神经氨酸酶抑制剂，具有抗病毒活性。 |
| M5055
|
Peramivir |
Peramivir（RWJ-270201，BCX-1812)是一种有效的，特异性的神经氨酸酶抑制剂（NAIs），其IC50 值为 0.9-4.3 nM，具有抗病毒活性，可用于流感病毒的相关研究。 |
| M5083
|
β-Cyclodextrin |
β-Cyclodextrin（β-环糊精，β-CD）是一种环状低聚糖，其基本结构单元为α-D-吡喃型葡萄糖，其分子结构呈中空的圆筒状，内部形成一个疏水性空腔，外部则带有亲水性的羟基。β-Cyclodextrin的疏水性空腔可以包合多种疏水性化合物，可提高化合物的溶解度、稳定性和生物利用度。 |
| M3357
|
Telbivudine |
Telbivudine (Epavudine) 是一种有效的乙型肝炎病毒 (HBV) 复制的抗病毒抑制剂。Telbivudine 是一种抗病毒化合物，用于乙型肝炎的研究。 |
| M1695
|
Cidofovir |
Cidofovir是一种具有抗病毒活性的化合物，通过选择性抑制病毒DNA的合成而抑制病毒复制。Cidofovir还具有抑制肿瘤生长的活性，可用于肿瘤的相关研究。 |
| M4718
|
Dendrobine |
Dendrobine 是从 Dendrobium nobile 中分离出的一种生物碱。Dendrobine 对甲型流感病毒具有抗病毒活性，对A/FM-1/1/47 (H1N1)、A/Puerto Rico/8/34 H274Y (H1N1) 和 A/Aichi/2/68 (H3N2) 作用 IC50 值分别为3.39 μM、 2.16 μM 、5.32 μM。 |
| M10421
|
Sodium citrate (dihydrate) |
Sodium citrate dehydrate 是一种抗凝血剂，也可用作缓冲剂和食品防腐剂。此外，Sodium citrate dehydrate 也可与柠檬酸构成缓冲体系，作为缓冲液使用。 |
| M3222
|
Peramivir Trihydrate |
Peramivir Trihydrate（BCX-1812 Trihydrate, RWJ-270201 Trihydrate, S-021812 Trihydrate，帕拉米韦三水合物）是一种有效的，特异性的神经氨酸酶抑制剂（NAIs），其IC50 值为 0.9-4.3 nM，具有抗病毒活性，可用于流感病毒的相关研究。 |
| M4789
|
Isoscopoletin |
Isoscopoletin (6-Hydroxy-7-methoxycoumarin) 是艾叶中的一种活性成分。 Isoscopoletin 具有显著的细胞增殖抑制作用，对人类 CCRF-CEM 白血病细胞和耐药亚系 CEM/ADR5000 作用的 IC50 值分别为 4.0 μM 和 1.6 μM。Isoscopoletin (6-Hydroxy-7-methoxycoumarin) 具有抑制 HBV 复制的活性。 |
| M11499
|
Tecovirimat |
Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) 是一种 antiviral 抗病毒类化合物，通过靶向病毒 p37 protein orthologs 来抑制正痘病毒orthopoxviruses的释放。Tecovirimat 被开发用于天花感染的研究。 |
| M21026
|
Garenoxacin |
Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes. |
| M20972
|
Besifovir |
Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection. |
| M20969
|
Methenamine Hippurate |
Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. |
| M20959
|
Fosfluconazole |
Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. |
| M20946
|
Butenafine |
Butenafine is a synthetic benzylamine antifungal agent. |
| M20945
|
Olanexidine Hydrochloride semihydrate |
Olanexidine is a monobiguanide compound with bactericidal activity. |
| M20944
|
Metronidazole Benzoate |
Metronidazole Benzoate is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. |
| M20940
|
Proflavine |
Proflavine is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings. |
| M20918
|
Butoconazole |
Butoconazole is an imidazole antifungal used in gynecology. |
| M20909
|
Isoprinosine |
Isoprinosine is an immunopharmacologic agent with antiviral activities. |
| M20907
|
Octenidine Dihydrochloride |
Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria. |
| M20885
|
KKL-10 |
KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria. |
| M20879
|
Amantadine |
Amantadine (1-Adamantanamine) 是一种具有口服活性的抗甲型流感 (influenza A) 病毒的抗病毒剂。Amantadine 对 NMDA、M2 等多种离子通道均有抑制作用。Amantadine 还具有抗正痘病毒 (orthopoxvirus) 和抗癌活性。 |
| M20801
|
PF-00835231 |
PF-00835231 is a 3CLpro (Mpro) inhibitor that may targets SARS-CoV-2 protease 3CLpro as a potential new treatment for COVID-19. |
| M20788
|
Ethacridine lactate |
Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. |
| M20694
|
Bay 41-4109 racemate |
BAY 41-4109 racemate is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM. |
| M20554
|
Proguanil |
Proguanil is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. |
| M20530
|
Oxantel Pamoate |
Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting. |
| M20526
|
Myclobutanil |
Myclobutanil is a conazole class fungicide widely used as an agrichemical. |
| M20435
|
Robenidine Hydrochoride |
Robenidine hydrochloride is an anticoccidial agent mainly for poultry. |
