找到约 5 条 “Vinblastine” 相关结果 （用时 0.158 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M3120
|
Vinorelbine Tartrate | 酒石酸长春瑞滨 | Microtubule |
| KW-2307; Nor-5'-anhydrovinblastine ditartrate | |||
| Vinorelbine Tartrate（酒石酸长春瑞滨）是一种半合成的长春花生物碱，并通过与微管蛋白（microtubule）相互作用抑制有丝分裂。 | |||
M3912
|
Vinblastine sulfate | 硫酸长春碱 | Microtubule |
| Vincaleukoblastine sulfate salt | |||
| Vinblastine sulfate（硫酸长春碱）是一种具有广谱抗肿瘤活性的生物碱，能够抑制细胞内微管的形成和有丝分裂。此外，它还能够抑制nAChR的活性，其IC50值为8.9μM。 | |||
| M4347
|
Vinblastine | 长春质碱 | Microtubule |
| Vinblastine（长春质碱）是从植物中分离的天然生物碱，可通过结合微管蛋白并抑制微管形成，导致有丝分裂纺锤体装配的破坏和肿瘤细胞在细胞周期M期的停滞。Vinblastine也可能干扰氨基酸、环腺苷酸和谷胱甘肽代谢，钙调蛋白依赖性钙离子转运ATP酶活性，细胞呼吸，以及核酸和脂质生物合成。 | |||
| M20720 | Vindesine sulfate | Vindesine sulfate | Microtubule |
| Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS | |||
| Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS), a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities. Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. | |||
| M7923 | Myoseverin B | Myoseverin B | Others |
| Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. | |||
