找到约 16 条 “SM16” 相关结果 （用时 0.544 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M5497
|
Cefpiramide sodium | 头孢匹胺钠 | Antibiotic |
| SM-1652; Wy-44635 | |||
| Cefpiramide sodium (头孢匹胺钠; Wy-44635; SM-1652) 是一种新的假单胞菌活性的广谱头孢菌素与抗菌活性。 | |||
| M6187
|
SM-164 | SM-164 | IAP |
| SM-164是可渗透细胞的Smac类似物，能与XIAP蛋白结合，Ki为0.56 nM，与cIAP-1和cIAP-2蛋白结合的Ki分别为0.31和1.1 nM。 | |||
| M9274
|
SMI-16a | SMI-16a | Pim |
| PIM1/2 Kinase Inhibitor VI | |||
| SMI-16a 是Pim-1/2激酶的有效的，细胞渗透性的，ATP竞争性抑制剂，对Pim1和Pim2的IC50值分别为150和20 nM。 | |||
| M9683
|
SM16 | SM16 | TGF-β Receptor |
| SM-16 | |||
| SM16是一种ALK5/4的激酶抑制剂，Ki值分别为10和1.5 nM。 | |||
| M13548
|
SM-164 Hydrochloride | SM-164 Hydrochloride | IAP |
| SM-164 Hydrochloride 是一种可渗透细胞的 Smac 类似物。SM-164 与含有 BIR2 和 BIR3 结构域的 XIAP 蛋白结合，IC50 值为 1.39 nM，SM-164 用作 XIAP 的强效拮抗剂。 | |||
| M19930
|
Cefpiramide acid | Cefpiramide acid | Anti-infection |
| Cefpiramide acid; Cefpiramido; Cefpiramidum; WY-44635; SM-1652 | |||
| Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity. | |||
| M21345
|
Recombinant Human CXCL16 (Pro49-Pro137) (E.coli) | 重组人CXCL16 (Pro49-Pro137) 蛋白 (E.coli) | Cytokines and Growth Factors |
| SR-PSOX，Small-inducible cytokine B16 | |||
| 蛋白构造：编码人类CXCL16（Pro49-Pro137）的DNA序列与GST标签融合。Accession #：Q9H2A7。 | |||
| M19986
|
Recombinant Human CXCL6 (HEK293, C-6His) | 重组人CXCL6 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| C-X-C Motif Chemokine 6; Chemokine Alpha 3 | |||
| Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162. | |||
| M28458 | SMN-C2 | SMN-C2 | DNA/RNA Synthesis |
| SMN-C2 ，RG-7916 的类似物，是一种选择性的 SMN2 基因剪接调节剂，通过结合 SMN2 pre-mRNA 起作用，从而增加远上游元件结合蛋白 1 (FUBP1) 和 KH 型剪接的 RNA 结合蛋白的亲和力调节蛋白 (KHSRP) 到 SMN2 pre-mRNA 复合物。SMN-C2 可用于脊髓性肌萎缩症 (SMA) 研究。 | |||
| M29187 | SM1-71 | SM1-71 | MAPKAPK2/MAP3K/MAP4K |
| SM1-71 是一种有效的 TAK1 抑制剂，Ki 值为 160 nM，同时可以共价抑制 MKNK2、MAP2K1/2/3/4/6/7、GAK、AAK1、BMP2K、MAP3K7、MAPKAPK5、GSK3A/B、MAPK1/3、SRC、YES1、FGFR1、ZAK (MLTK)、MAP3K1、LIMK1 和 RSK2。SM1-71 在体外抑制多种癌细胞系的增殖。 | |||
| M29454 | ZK824190 | ZK824190 | Serine/Threonine Protease |
| ZK824190 是一种口服有效的选择性尿激酶型纤溶酶原激活剂 (uPA) 抑制剂，可用于多发性硬化症的研究。ZK824190 对 uPA，tPA 和 Plasmin 的 IC50 分别为 237，1600 和 1850 nM。 | |||
| M29739 | ZK824190 hydrochloride | ZK824190 hydrochloride | Serine/Threonine Protease |
| ZK824190 hydrochloride 是一种口服有效的选择性尿激酶型纤溶酶原激活剂 (uPA) 抑制剂，可用于多发性硬化症的研究。ZK824190 hydrochloride 对 uPA，tPA 和 Plasmin 的 IC50 分别为 237，1600 和 1850 nM。 | |||
| M55679
|
Recombinant Human CA125 Protein (HEK293, C-6His) | 重组人CA125 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| FLJ14303; MUC16; mucin 16 | |||
| CA125 is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. CA125 binds galectin-1 on immune cells and enhances its expression on tumor cells. CA125-expressing tumors adhere to NK cells, down-regulate CD16 and suppress NK response, which may promote immune evasion. | |||
| M56267 | Desmethyl-YM-298198 hydrochloride | Desmethyl-YM-298198 hydrochloride | GluR |
| Desmethyl-YM-298198 Hydrochloride 是一种高亲和力、选择性、非竞争性 mGluR1 拮抗剂 (IC50: 16 nM)。Desmethyl-YM-298198 Hydrochloride 对 Streptozotocin 诱导的痛觉过敏小鼠具有镇痛作用。 | |||
| M56271 | Desmethyl-YM-298198 | Desmethyl-YM-298198 | GluR |
| Desmethyl-YM-298198 是一种高亲和力、选择性、非竞争性 mGluR1 拮抗剂 (IC50: 16 nM)。Desmethyl-YM-298198 对 Streptozotocin 诱导的痛觉过敏小鼠具有镇痛作用。 | |||
| M58101
|
Recombinant Human EGFR Protein (CHO, C-His) | 重组人EGFR 蛋白 (CHO, C-His) | Cytokines and Growth Factors |
| ERBB; ERBB1; HER1; Epidermal Growth Factor Receptor | |||
| EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. | |||
