找到约 8 条 “PRIMA-1” 相关结果 （用时 0.204 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M7994
|
PRIMA-1 | PRIMA-1 | p53 |
| PRIMA-1 是一种突变型 p53 复活剂，可恢复 TP53 突变型甲状腺癌细胞对组蛋白甲基化抑制剂 3-Deazaneplanocin A 的敏感性。 | |||
| M9623
|
APR-246 (Eprenetapopt) | 埃普雷塔波普 | p53 |
| PRIMA-1MET; Eprenetapopt | |||
| APR-246 (Eprenetapopt、PRIMA-1Met)是一种首创的（first-in-class）突变型p53重激活剂，能诱导线粒体释放BAX依赖的细胞色素c，抑制硒蛋白硫氧还蛋白还原酶 1 (TrxR1)。 | |||
| M20395 | Tetrabenazine (Xenazine) | Tetrabenazine (Xenazine) | Dopamine Receptor |
| Tetrabenazine(Nitoman, Xenazine) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2 Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2. | |||
| M25427
|
Recombinant Human SDF-1 Protein (E. coli) | 重组人SDF-1蛋白 (E. coli) | Cytokines and Growth Factors |
| Stromal cell-derived factor-1 | |||
| The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription. | |||
| M25484
|
Recombinant Human HBAZ Protein (E.coli, N-6His) | 重组人HBAZ蛋白 (E.coli, N-6His) | Cytokines and Growth Factors |
| Hemoglobin Subunit Zeta | |||
| Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal growth and adult life. Recombinant Human Hemoglobin Subunit Zeta is produced by our E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus. | |||
| M28405 | Pritelivir mesylate hydrate | Pritelivir mesylate hydrate | Anti-infection |
| AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate | |||
| Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate) 是一种病毒解旋酶-引物酶复合物 (helicase-primase complex) 抑制剂，在体外和单纯疱疹病毒 (HSV) 感染的动物模型中均具有抗病毒活性。Pritelivir mesylate hydrate 对 1 型和 2 型单纯疱疹病毒 (HSV-1 和 HSV-2) 具有活性，对 HSV1-2 的 IC50 为 0.02 μM。 | |||
| M28406 | Pritelivir mesylate | Pritelivir mesylate | Anti-infection |
| AIC316 mesylate; BAY 57-1293 mesylate | |||
| Pritelivir mesylate (BAY 57-1293 mesylate) 是一种病毒解旋酶-引物酶复合物 (helicase-primase complex) 抑制剂，在体外和单纯疱疹病毒 (HSV) 感染的动物模型中均具有抗病毒活性。Pritelivir mesylate 对 1 型和 2 型单纯疱疹病毒 (HSV-1 和 HSV-2) 具有活性，对 HSV1-2 的 IC50 为 0.02 μM。 | |||
| M43958
|
Recombinant Rat SDF-1/CXCL12 (E. coli) | 重组大鼠SDF-1/CXCL12 (E. coli) | Cytokines and Growth Factors |
| Stromal-Cell Derived Factor-1 alpha; CXCL12 alpha | |||
| SDF-1 also known as CXCL12 is belonging to the CXC chemokine family. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription. | |||
