找到约 6 条 “MMP2-IN-1” 相关结果 （用时 0.126 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M58413 | MMP2-IN-1 | MMP2-IN-1 | MMP |
| MMP2-IN-1 是一种中等效力的 MMP2 抑制剂，其 IC50 值为 6.8 µM。MMP2-IN-1 通过抑制细胞周期和诱导细胞凋亡，对某些癌细胞具有显著的抗增殖活性。 | |||
M21685
|
Recombinant Human MMP-1 (HEK293, C-6His) | 重组人MMP-1 蛋白(HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-1 | |||
| Recombinant Human MMP-1可降解多种底物，包括 I、II、III、VII、VIII 和 X 型胶原蛋白以及酪蛋白、明胶、α1 抗胰蛋白酶、髓磷脂碱性蛋白、L-选择蛋白、pro-TNF、IL1、IGFBP3 、IGFBP5、pro-MMP2 和 pro-MMP9。Recombinant Human Matrix Metalloproteinase-1 由哺乳动物表达系统产生，编码 Phe20-Asn469 的靶基因在 C 末端用 6His 标签表达。酶原需要被 APMA 激活以获得激活形式。 | |||
| M28847 | MMP2-IN-2 | MMP2-IN-2 | MMP |
| MMP2-IN-2 (化合物 42) 是一种有效且选择性的 MMP-2 (基质金属蛋白酶)抑制剂，其 IC50 值为 4.2 μM。MMP2-IN-2 对 MMP-13、MMP-9 和 MMP-8 也表现出抑制活性，其 IC50 分别为 12、23.3 和 25 μM。 | |||
| M31127
|
Recombinant Human MMP-2 Protein (HEK293, C-6His) | 重组人MMP-2蛋白 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-2; Gelatinase A | |||
| Recombinant Human MMP-2 (also known as matrix metalloproteinase-2) is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. The proenzyme needs to be activated by APMA for an activated form. | |||
| M43969
|
Recombinant Mouse MMP-12 (HEK293, C-6His) | 重组小鼠MMP-12 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-12 | |||
| Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. | |||
| M43971
|
Recombinant Human MMP12 Protein (E. coli) | 重组人MMP12 蛋白 (E. coli) | Enzymes & Regulators |
| Matrix metalloproteinase-12 | |||
| Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. | |||
