找到约 14 条 “Galectin” 相关结果 （用时 0.556 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M21457
|
Recombinant Human Galectin 9 (Human Cells, C-6His) | 重组人Galectin 9蛋白 (Human Cells, C-6His) | Cytokines and Growth Factors |
| Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21 | |||
| 重组人Galectin 9由人类细胞表达系统产生，编码Met1-Thr323的目的基因在c端用6His标记表达。蛋白编号：Q3B8N1-2。 | |||
| M41982 | Galectin-3/galectin-8-IN-1 | Galectin-3/galectin-8-IN-1 | Galectin |
| Galectin-3/galectin-8-IN-1 是一种双重 Galectin-3 和 galectin-8 C 末端结构域抑制剂，K d 值分别为 4.12 μM 和 6.04 μM。 | |||
| M41983 | Galectin-3/galectin-8-IN-2 | Galectin-3/galectin-8-IN-2 | Galectin |
| Galectin-3/galectin-8-IN-2 是一种双重 Galectin-3 和 galectin-8 C 末端结构域抑制剂，Kd 值分别为 12.8 μM 和 2.06 μM。 | |||
| M41984 | Galectin-3 antagonist 1 | Galectin-3 antagonist 1 | Galectin |
| Galectin-3 antagonist 1 是一种有效的选择性 Galectin-3 (Gal-3) 拮抗剂，Kd 值为 5.3 μM。 | |||
| M58154
|
Recombinant Mouse Galectin-1/LGALS1 Protein (E. coli) | 重组小鼠Galectin-1/LGALS1 蛋白 (E. coli) | Cytokines and Growth Factors |
| Gal-1; Galbp; Lect14 Protein | |||
| Galectin-1/LGALS1 is a member of the galectins. Galectin-1 contributes to different steps of tumor progression including cell adhesion, migration, and tumor-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. | |||
| M58507
|
Recombinant Human Galectin-3 Protein (HEK293, C-His) | 重组人Galectin-3 蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| LGALS3 | |||
| Human Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain. LGALS3 (Galectin 3) has an important role in tumor progression through inhibition of apoptosis. | |||
| M9324
|
TD139 | TD139 | Galectin |
| TD-139; GB0139; Olitigaltin | |||
| TD-139（Olitigaltin）是一种新的有效的galectin-3（半乳糖凝集素-3）小分子抑制剂，能浓度依赖性地抑制Galectin-3增强的血小板活化，并抑制闭塞性血栓和微血管血栓的形成，同时具有潜在的抗纤维化活性，可用于特发性肺纤维的相关研究。 | |||
| M9897
|
GB1107 | GB1107 | Galectin |
| GB-1107 | |||
| GB1107是一种口服活性的Galectin-3抑制剂，Kd值为37 nM。GB1107能抑制人和小鼠肺腺癌的生长。GB1107能增强PD-L1免疫检查点抑制剂的作用，增加细胞毒性（IFNγ、颗粒酶B、穿孔蛋白-1、Fas配体）和凋亡（裂解的caspase-3）效应分子的表达。 | |||
| M14088
|
OTX008 | OTX008 | Galectin |
| Calixarene 0118; PTX008 | |||
| OTX008 是一个半乳糖凝集素 1 (galectin-1) 的选择性抑制剂。 | |||
| M22469
|
G3-C12 | G3-C12 | Galectin |
| G3-C12 是一种 galectin-3 结合肽，Kd 值为 88 nM，具有抗肿瘤活性。 | |||
| M29075 | Selvigaltin | Selvigaltin | Galectin |
| GB1211 | |||
| Selvigaltin (GB1211) 是一种具有口服活性的 galectin-3 (Gal-3) 抑制剂。 | |||
| M40747 | Belapectin | Belapectin | Galectin |
| GR-MD-02 | |||
| Belapectin是一种半乳糖凝集素3（galectin 3）抑制剂，其Ki值为 2.8 μM，能减少大鼠肝纤维化和门静脉高血压，可用于非酒精性脂肪性肝炎(NASH)的相关研究。 | |||
| M45360
|
LYT-200 | LYT-200 | Galectin |
| Anti-Human LGALS9 | |||
| Research Grade Anti-Human LGALS9 (LYT-200) 是一种靶向半乳糖凝集素-9（galectin-9）的单克隆抗体，并具有抗肿瘤活性。 | |||
| M55679
|
Recombinant Human CA125 Protein (HEK293, C-6His) | 重组人CA125 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| FLJ14303; MUC16; mucin 16 | |||
| CA125 is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. CA125 binds galectin-1 on immune cells and enhances its expression on tumor cells. CA125-expressing tumors adhere to NK cells, down-regulate CD16 and suppress NK response, which may promote immune evasion. | |||
