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Recombinant Human Galectin 9 (Human Cells, C-6His) 重组人Galectin 9蛋白 (Human Cells, C-6His)

目录号 M21457 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人Galectin 9由人类细胞表达系统产生,编码Met1-Thr323的目的基因在c端用6His标记表达。蛋白编号:Q3B8N1-2。

Recombinant Human Galectin 9 (Human Cells, C-6His)结构式

别名:Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21

规格 价格 库存状态
10ug ¥ 1638 中国库存现货
50ug ¥ 3600 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin<1 EU/µg
  • COA
  • MSDS
生物活性

种属:Human

表达系统:Human Cells

纯度:经还原SDS-PAGE测定,大于95%

内毒素:LAL测试测得小于0.1 ng/µg (1eu /µg)

分子量:36.7 KDa

存储及稳定性:冻干蛋白应在< -20℃下保存,但在室温下可稳定保存3周。重组蛋白溶液可在4-7℃保存2-7天。、重组样品的等分线在< -20°C下稳定3个月。


生物活性:半乳糖凝集素-9是一种含有两个半乳糖凝集素结构域的细胞质蛋白。半乳糖凝集素-9是一种s型凝集素,在何杰金氏病组织中过度表达。半乳糖凝集素-9结合半乳糖苷,对福斯曼五糖有较高的亲和力。半乳糖凝集素-9在胸腺细胞-上皮细胞的相互作用中起作用,与胸腺的生物学相关,并抑制细胞增殖。Galectin-9是HAVCR2/TIM3的配体,可诱导t辅助性1型淋巴细胞(Th1)死亡。此外,Galectin-9通过干扰CD44、VCAM-1、Integrin α4β1等因子的作用抑制肿瘤细胞转移。

化学性质
溶解性(25°C) It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 粉末型式       -20°C   3年;4°C   2年
溶于溶剂       -80°C   6个月;-20°C   1个月
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Asahiro Morishita, et al. Oncol Rep. Galectin‑9 suppresses the tumor growth of colon cancer in vitro and in vivo

[2] Zhi-Hui Li, et al. Front Immunol. Galectin-9 Alleviates LPS-Induced Preeclampsia-Like Impairment in Rats via Switching Decidual Macrophage Polarization to M2 Subtype

[3] Mohamed Abdel-Mohsen, et al. PLoS Pathog. Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

[4] Shintaro Fujihara, et al. Recent Pat Endocr Metab Immune Drug Discov. Galectin-9 in cancer therapy

[5] Valerie R Wiersma, et al. Med Res Rev. Therapeutic potential of Galectin-9 in human disease

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