找到约 58 条 “Fluo-3” 相关结果 （用时 0.049 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M3877
|
4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | Others |
| 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | |||
| M5651
|
Flucytosine | 氟胞嘧啶 | DNA/RNA Synthesis |
| 5-Fluorocytosine; NSC 103805; Ro 2-9915 | |||
| Flucytosine（ 5-Fluorocytosine，5-FC，Ancobon，氟胞嘧啶）是一种胞嘧啶类似物，具有抗真菌活性。在穿透进入真菌细胞后，Flucytosine脱氨基变为其活性代谢物5-氟尿嘧啶。5-氟尿嘧啶可中断核苷酸代谢和DNA合成，并最终中断蛋白质合成。 | |||
| M8479 | Pyr6 | Pyr6 | Others |
| N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide | |||
| Pyr6 is a selective inhibitor of calcium release from the endoplasmic reticulum via STIM1/Orai1 mediated, store operated calcium entry (SOCE). | |||
| M9960
|
Fluo 3-AM | 钙离子荧光探针FLUO-3, AM | Fluorescent Dye |
| Fluo 3-AM是一种细胞内Ca2+渗透性荧光指示剂，在细胞内被水解或在Ca2+存在下发出荧光。 | |||
| M11583 | ChemBridge-5101031 | ChemBridge化合物-5101031 | Screening Compounds and Building Blocks |
| N-(4-nitrophenyl)-N'-pentyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine (5101031) | |||
| ChemBridge特有类药化合物/先导化合物-5101031，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11584 | ChemBridge-5101039 | ChemBridge化合物-5101039 | Screening Compounds and Building Blocks |
| N-methyl-N'-(4-nitrophenyl)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine (5101039) | |||
| ChemBridge特有类药化合物/先导化合物-5101039，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11644 | ChemBridge-5118984 | ChemBridge化合物-5118984 | Screening Compounds and Building Blocks |
| 4-(3,4-difluorophenyl)-1,3-thiazol-2-amine (5118984) | |||
| ChemBridge特有类药化合物/先导化合物-5118984，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11675 | ChemBridge-5135308 | ChemBridge化合物-5135308 | Screening Compounds and Building Blocks |
| 9H-fluoren-1-ol (5135308) | |||
| ChemBridge特有类药化合物/先导化合物-5135308，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11678 | ChemBridge-5136251 | ChemBridge化合物-5136251 | Screening Compounds and Building Blocks |
| 3-(3-fluorophenyl)-1-(5-methyl-2-furyl)-2-propen-1-one (5136251) | |||
| ChemBridge特有类药化合物/先导化合物-5136251，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11806 | ChemBridge-5205327 | ChemBridge化合物-5205327 | Screening Compounds and Building Blocks |
| N,N-dibenzyl-1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexanecarboxamide (5205327) | |||
| ChemBridge特有类药化合物/先导化合物-5205327，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11824 | ChemBridge-5213291 | ChemBridge化合物-5213291 | Screening Compounds and Building Blocks |
| 4,4-difluoro-3,5-dihydroxy-1,7-diphenyl-2,5-heptadiene-1,7-dione (5213291) | |||
| ChemBridge特有类药化合物/先导化合物-5213291，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11826 | ChemBridge-5213395 | ChemBridge化合物-5213395 | Screening Compounds and Building Blocks |
| 4-fluorobenzaldehyde (1-oxido-4-quinolinyl)hydrazone (5213395) | |||
| ChemBridge特有类药化合物/先导化合物-5213395，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11883 | ChemBridge-5234250 | ChemBridge化合物-5234250 | Screening Compounds and Building Blocks |
| 2,4-dibromo-6-{[(2-chlorobenzoyl)amino]methyl}phenyl 4-fluorobenzoate (5234250) | |||
| ChemBridge特有类药化合物/先导化合物-5234250，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11887 | ChemBridge-5236422 | ChemBridge化合物-5236422 | Screening Compounds and Building Blocks |
| 4-chloro-N-[4-(4-fluorobenzoyl)phenyl]benzenesulfonamide (5236422) | |||
| ChemBridge特有类药化合物/先导化合物-5236422，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11903 | ChemBridge-5244593 | ChemBridge化合物-5244593 | Screening Compounds and Building Blocks |
| (4-fluorophenyl)(3-pyridinyl)methanone (5244593) | |||
| ChemBridge特有类药化合物/先导化合物-5244593，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11935 | ChemBridge-5265182 | ChemBridge化合物-5265182 | Screening Compounds and Building Blocks |
| 5-(4-fluorobenzylidene)-1,3-thiazolidine-2,4-dione (5265182) | |||
| ChemBridge特有类药化合物/先导化合物-5265182，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11948 | ChemBridge-5273561 | ChemBridge化合物-5273561 | Screening Compounds and Building Blocks |
| 2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (5273561) | |||
| ChemBridge特有类药化合物/先导化合物-5273561，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12000 | ChemBridge-5326487 | ChemBridge化合物-5326487 | Screening Compounds and Building Blocks |
| N'-(3-bromo-4-methoxybenzylidene)-3-fluorobenzohydrazide (5326487) | |||
| ChemBridge特有类药化合物/先导化合物-5326487，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12010 | ChemBridge-5342191 | ChemBridge化合物-5342191 | Screening Compounds and Building Blocks |
| N-[4-chloro-3-(trifluoromethyl)phenyl]-7-nitro-2,1,3-benzoxadiazol-4-amine (5342191) | |||
| ChemBridge特有类药化合物/先导化合物-5342191，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12014 | ChemBridge-5348017 | ChemBridge化合物-5348017 | Screening Compounds and Building Blocks |
| 1-(4-fluorophenyl)-1,2-butanedione 2-oxime (5348017) | |||
| ChemBridge特有类药化合物/先导化合物-5348017，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12042 | ChemBridge-5367380 | ChemBridge化合物-5367380 | Screening Compounds and Building Blocks |
| N,N'-[[(4-fluorophenyl)methylene]bis(2,6-dimethyl-4,1-phenylene)]dibenzamide (5367380) | |||
| ChemBridge特有类药化合物/先导化合物-5367380，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12047 | ChemBridge-5376883 | ChemBridge化合物-5376883 | Screening Compounds and Building Blocks |
| 2-thioxo-5-({5-[3-(trifluoromethyl)phenyl]-2-furyl}methylene)-1,3-thiazolidin-4-one (5376883) | |||
| ChemBridge特有类药化合物/先导化合物-5376883，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12054 | ChemBridge-5378142 | ChemBridge化合物-5378142 | Screening Compounds and Building Blocks |
| 5-(3-fluorobenzylidene)-1,3-thiazolidine-2,4-dione (5378142) | |||
| ChemBridge特有类药化合物/先导化合物-5378142，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12062 | ChemBridge-5398003 | ChemBridge化合物-5398003 | Screening Compounds and Building Blocks |
| 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile (5398003) | |||
| ChemBridge特有类药化合物/先导化合物-5398003，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12075 | ChemBridge-5416437 | ChemBridge化合物-5416437 | Screening Compounds and Building Blocks |
| 1-{4-[4-(2,5-difluorobenzyl)-1-piperazinyl]phenyl}ethanone (5416437) | |||
| ChemBridge特有类药化合物/先导化合物-5416437，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12079 | ChemBridge-5432053 | ChemBridge化合物-5432053 | Screening Compounds and Building Blocks |
| 1-[3-(benzyloxy)benzyl]-4-(2-fluorophenyl)piperazine (5432053) | |||
| ChemBridge特有类药化合物/先导化合物-5432053，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12081 | ChemBridge-5455773 | ChemBridge化合物-5455773 | Screening Compounds and Building Blocks |
| 4-{3-[(2-fluorophenyl)amino]butyl}phenol (5455773) | |||
| ChemBridge特有类药化合物/先导化合物-5455773，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12082 | ChemBridge-5461326 | ChemBridge化合物-5461326 | Screening Compounds and Building Blocks |
| 4-{[(3-chloro-4-fluorophenyl)amino]methyl}phenol (5461326) | |||
| ChemBridge特有类药化合物/先导化合物-5461326，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12100 | ChemBridge-5480351 | ChemBridge化合物-5480351 | Screening Compounds and Building Blocks |
| 10-{3-[4-(2-adamantyl)-1-piperazinyl]propanoyl}-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride (5480351) | |||
| ChemBridge特有类药化合物/先导化合物-5480351，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12183 | ChemBridge-5613645 | ChemBridge化合物-5613645 | Screening Compounds and Building Blocks |
| 1-[(4-fluorophenyl)sulfonyl]-2-methyl-1H-benzimidazole (5613645) | |||
| ChemBridge特有类药化合物/先导化合物-5613645，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M2865
|
Sodium Monofluorophosphate | 单氟磷酸钠 | Pyruvate Kinase |
| Sodium Monofluorophosphate 是一种竞争性的丙酮酸激酶（PK）和碱性磷酸酶（ALP）抑制剂，Ki分别为3.4 mM和69 μM，也不可逆地抑制磷酸化酶磷酸酶（phosphorylase phosphatase），Ki为0.5 mM。 | |||
| M6505
|
BIBO 3304 trifluoroacetate | BIBO 3304 trifluoroacetate | Neuropeptide Receptor |
| BIBO 3304 trifluoroacetate（BIBO 3304三氟乙酸酯）是一种精氨酸酰胺衍生物，同时也是选择性的，高亲和力的NPY Y1受体拮抗剂，作用于人类和大鼠的Y1受体上时，IC50值分别为0.38±0.06 nM和0.72±0.42 nM，具有抗焦虑活性。 | |||
| M6748
|
GGTI 298 Trifluoroacetate | GGTI 298 Trifluoroacetate | Ras |
| GGTI298 TFA | |||
| GGTI 298 Trifluoroacetate 是一种有效的 GGTase I 抑制剂，抑制 Rap1A 的 IC50 值为3μM。 | |||
| M7437 | TWS 119 Trifluoroacetate | TWS 119 Trifluoroacetate | Others |
| TWS 119 Trifluoroacetate is a gSK-3β inhibitor; induces neuronal differentiation in ESCs. | |||
| M7591
|
Arachidonyl trifluoromethyl ketone | 花生四烯基三氟甲酮 | Phospholipase |
| AACOCF3 | |||
| Arachidonyl trifluoromethyl ketone（AACOCF3）是胞质磷脂酶A2（cPLA2）的有效选择性慢结合抑制剂，它通过与cPLA2的活性位点结合，阻止该酶催化花生四烯酸（AA）从膜磷脂中的释放。AACOCF3还能阻断花生四烯酸代谢途径，可用于抗炎、镇痛和抗过敏的研究。在实验中，AACOCF3还能抑制离体大鼠胰岛组织中葡萄糖诱导的胰岛素分泌。 | |||
| M8470
|
SB290157 trifluoroacetate salt | SB290157 trifluoroacetate salt | Complement System |
| SB290157 TFA | |||
| SB290157 trifluoroacetate是一种选择性的C3a受体的拮抗剂，IC50值为200 nM。 | |||
| M8605 | NA-17 | NA-17 | Others |
| NA-17 is a fluorescent naphthalimide that induces accumulation of activated p53 in mitochondria and nuclei of NSCLC cells. | |||
M10272
|
Fluorescein Sodium | 荧光素钠 | Fluorescent Dye |
| Fluorescein Sodium（荧光素钠）是一种橙色水溶性荧光染料（Fluorescent Dye），在正常泪膜中呈黄绿色，在碱性更强的介质（如房水）中呈亮绿色。能吸收465-490 nm范围内的光(蓝光)，并发射520-530 nm范围内的光(绿光)，可用于眼底荧光血管造影术（FFA）和荧光引导手术中的造影剂。 | |||
| M10728
|
Cyclo(RGDyK) trifluoroacetate | Cyclo(RGDyK) trifluoroacetate | Integrin |
| Cyclo(RGDyK) trifluoroacetate 是一种有效的选择性 αVβ3 整联蛋白 (integrin) 抑制剂，IC50 为 20 nM。 | |||
| M13784
|
Fluorescein di (β-D-galactopyranoside) | Fluorescein di (β-D-galactopyranoside) | Fluorescent Dye |
| FDG | |||
| Fluorescein di (β-D-galactopyranoside) 是 β-半乳糖苷酶的荧光底物 (λex=485 nm，λem=535 nm)。 | |||
| M14064 | Pasireotide ditrifluoroacetate | 帕瑞肽二三氟乙酸盐 | Others |
| SOM230 ditrifluoroacetate; Pasireotide TFA salt | |||
| Pasireotide (SOM230) ditrifluoroacetate 是一种长效的环己肽生长激素抑制素类似物，同时也是大环类化合物，可以提高生长抑素受体(SSTR)的激动剂活性，对 sst1/2/3/4/5 的 pKi 分别为 8.2/9.0/9.1/<7.0/9.9。Pasireotide ditrifluoroacetate 具有抗分泌、抗增殖和促凋亡活性。 | |||
| M14232 | Rapastinel Trifluoroacetate | Rapastinel Trifluoroacetate | GluR |
| GLYX-13 Trifluoroacetate | |||
| Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) 是一种具有甘氨酸位点部分激动剂性质的 NMDA 受体调节剂。Rapastinel Trifluoroacetate 有潜力用于抑郁症的研究 | |||
| M14503 | GSK256066 Trifluoroacetate | GSK256066 Trifluoroacetate | PDE |
| GSK256066 Trifluoroacetate 是一种选择性、高亲和力的 PDE 抑制剂，抑制 PDE4B 的 IC50 值为 3.2 pM。GSK256066 Trifluoroacetate 被开发用于慢性阻塞性肺病的研究。 | |||
| M17927 | tert-Butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate | 奥拉帕尼N-2；奥拉帕尼中间体N-2 | Others |
| tert-Butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate 奥拉帕尼N-2 | |||
| M19867
|
Gatifloxacin hydrochloride | Gatifloxacin hydrochloride | Topoisomerase |
| AM-1155 hydrochloride; CG5501 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride | |||
| Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively. | |||
| M20702 | Alovudine | Alovudine | Reverse Transcriptase |
| CL 184824, FddThd, FLT, MIV-310 | |||
| 3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer. | |||
| M20838 | Fluorofenidone | Fluorofenidone | Others |
| AKF-PD | |||
| Fluorofenidone (AKF-PD) inhibits nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase, NOX) via PI3K/Akt pathway in the pathogenesis of renal interstitial fibrosis. Fluorofenidone also attenuates BLM-induced pulmonary inflammation and fibrosis through suppressing the activation of NALP3 inflammasome and the IL-1β/IL-1R1/MyD88/NF-κB signalling pathway. | |||
| M22505
|
Recombinant Enhanced Green Fluorecence Protein (E. coli) | 重组增强型绿色荧光蛋白 (E. coli) | Cytokines and Growth Factors |
| reGFP; EGFP | |||
| 重组增强型绿色荧光蛋白（Enhanced Green Fluorecence Protein）是一种 26.9 kDa 的蛋白质（由 239 个氨基酸残基组成），在短波光（蓝色到紫外线）下显示绿色荧光。增强型 GFP (eGFP) 具有 S65T 和 F64L 突变，分别使 GFP 在 37℃ 下显示出更多的荧光和更有效地折叠。 | |||
| M28255 | Fluorizoline | Fluorizoline | Apoptosis |
| Fluorizoline 选择性地直接结合到 prohibitin 1 (PHB1) 和 2 (PHB2)，并诱导凋亡。Fluorizoline 通过上调 NOXA 和 BIM 降低慢性淋巴细胞性白血病 (CLL) 细胞的活力。Fluorizoline 以 p53 非依赖性方式发挥抗肿瘤作用。 | |||
| M39543 | 2-Fluoro-3-methoxyphenylboronic acid | 2-Fluoro-3-methoxyphenylboronic acid | Others |
| 2-Fluoro-3-methoxyphenylboronic acid 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M42310 | hCYP3A4 Fluorogenic substrate 1 | hCYP3A4 Fluorogenic substrate 1 | Cytochrome P450 (e.g. CYP17) |
| hCYP3A4 Fluorogenic substrate 1 是一种强效 hCYP3A4 荧光底物，Km 值为 0.36 μM。 | |||
| M43868 | 3-[6-(4-Amino-1-piperidinyl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | 3-[6-(4-Amino-1-piperidinyl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | Ligand for E3 Ligase |
| 3-[6-(4-Amino-1-piperidinyl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | |||
| M43870 | 3-[6-(2,6-Diazaspiro[3.3]hept-2-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | 3-[6-(2,6-Diazaspiro[3.3]hept-2-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | Ligand for E3 Ligase |
| 3-[6-(2,6-Diazaspiro[3.3]hept-2-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | |||
| M43871 | 3-[6-(2,7-Diazaspiro[3.5]non-7-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | 3-[6-(2,7-Diazaspiro[3.5]non-7-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | Ligand for E3 Ligase |
| 3-[6-(2,7-Diazaspiro[3.5]non-7-yl)-5-fluoro-3-pyridinyl]-2,6-piperidinedione | |||
| M45082 | Fluo-3 | 荧光钙探针 | Fluorescent Dye |
| Fluo-3是一种细胞内钙(Ca2+)的荧光指示剂，钙结合后荧光强度增加约40倍，可用于流式细胞术和共聚焦激光扫描显微镜。 | |||
| M45139 | Vari Fluor 488 SE | Vari Fluor 488 SE | Fluorescent Dye |
| VF 488 SE | |||
| Vari Fluor 488 SE是一种 Vari Fluor SE 系列的标记染料 (Ex/Em=488 nm/513 nm)。Vari Fluor SE 系列染料是一类含有 NHS 酯基的荧光染料，可用于标记抗体、蛋白质、肽、胺修饰的寡核苷酸和其他生物分子上的游离胺 (-NHX)。 | |||
| M45143 | Vari Fluor 350 SE | Vari Fluor 350 SE | Fluorescent Dye |
| VF 350 SE | |||
| Vari Fluor 350 SE是一种 Vari Fluor SE 系列的标记染料 (Ex/Em=350 nm/448 nm)。Vari Fluor SE 系列染料是一类含有 NHS 酯基的荧光染料，可用于标记抗体、蛋白质、肽、胺修饰的寡核苷酸和其他生物分子上的游离胺 (-NHX)。 | |||
| M45144 | Vari Fluor 565 SE | Vari Fluor 565 SE | Fluorescent Dye |
| VF 565 SE | |||
| Vari Fluor 565 SE是一种 Vari Fluor SE 系列的标记染料 (Ex/Em=563 nm/594 nm)。Vari Fluor SE 系列染料是一类含有 NHS 酯基的荧光染料，可用于标记抗体、蛋白质、肽、胺修饰的寡核苷酸和其他生物分子上的游离胺 (-NHX)。 | |||
