找到约 38 条 “Ex26” 相关结果 （用时 0.318 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M8611 | Ex26 | Ex26 | S1P Receptor |
| Ex26 is a peripherally-restricted biphenylcarboxamide derivative that acts as a highly potent and subtype-selective S1P1 antagonist (IC50 = 0.93 nM against S1PR1 and >3.1 μM against S1PR2/3/4/5). | |||
| M12007 | ChemBridge-5340426 | ChemBridge化合物-5340426 | Screening Compounds and Building Blocks |
| 5-nitro-N-(4-nitrophenyl)spiro[benzimidazole-2,1'-cyclohexan]-4-amine (5340426) | |||
| ChemBridge特有类药化合物/先导化合物-5340426，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12036 | ChemBridge-5362611 | ChemBridge化合物-5362611 | Screening Compounds and Building Blocks |
| 8-cyclohexyl-3-methyl-5,6-dihydro-4H-pyrazino[3,2,1-jk]carbazol-3-ium iodide (5362611) | |||
| ChemBridge特有类药化合物/先导化合物-5362611，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12351 | ChemBridge-5782601 | ChemBridge化合物-5782601 | Screening Compounds and Building Blocks |
| 1-cyclohexyl-2-(2,6-difluorobenzyl)octahydropyrrolo[1,2-a]pyrazine (5782601) | |||
| ChemBridge特有类药化合物/先导化合物-5782601，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12816 | ChemBridge-6942646 | ChemBridge化合物-6942646 | Screening Compounds and Building Blocks |
| 4-methoxybenzyl 2-methyl-5-oxo-4,7-di-2-thienyl-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate (6942646) | |||
| ChemBridge特有类药化合物/先导化合物-6942646，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M45570 | ChemBridge-5380726 | ChemBridge化合物-5380726 | Screening Compounds and Building Blocks |
| 9-[5-(2-chloro-4-nitrophenyl)-2-furyl]-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione (5380726) | |||
| ChemBridge特有类药化合物/先导化合物-5380726，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M45764 | ChemBridge-5962677 | ChemBridge化合物-5962677 | Screening Compounds and Building Blocks |
| methyl 4-(9-ethyl-9H-carbazol-3-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate (5962677) | |||
| ChemBridge特有类药化合物/先导化合物-5962677，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M45769 | ChemBridge-5972682 | ChemBridge化合物-5972682 | Screening Compounds and Building Blocks |
| 3,3,7,8-tetramethyl-11-(1-naphthyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (5972682) | |||
| ChemBridge特有类药化合物/先导化合物-5972682，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M46029 | ChemBridge-6966262 | ChemBridge化合物-6966262 | Screening Compounds and Building Blocks |
| 9-[3-methoxy-4-(1-naphthylmethoxy)phenyl]-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione (6966262) | |||
| ChemBridge特有类药化合物/先导化合物-6966262，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M46626 | ChemBridge-8877026 | ChemBridge化合物-8877026 | Screening Compounds and Building Blocks |
| 1-[1-(3-methylphenyl)-1H-tetrazol-5-yl]-N-(3-nitrobenzylidene)cyclohexanamine (8877026) | |||
| ChemBridge特有类药化合物/先导化合物-8877026，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47210 | ChemBridge-9324263 | ChemBridge化合物-9324263 | Screening Compounds and Building Blocks |
| 2-[3-(2-chlorophenyl)-6-oxo-1(6H)-pyridazinyl]-N-[2-(1-cyclohexen-1-yl)ethyl]acetamide (9324263) | |||
| ChemBridge特有类药化合物/先导化合物-9324263，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47215 | ChemBridge-9326888 | ChemBridge化合物-9326888 | Screening Compounds and Building Blocks |
| N-[2-(1-cyclohexen-1-yl)ethyl]-4-oxo-7,8-dihydro-4H,6H-cyclopenta[4,5][1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (9326888) | |||
| ChemBridge特有类药化合物/先导化合物-9326888，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47582 | ChemBridge-22242676 | ChemBridge化合物-22242676 | Screening Compounds and Building Blocks |
| N-[(1-hydroxycyclohexyl)methyl]-2-[1-(3-methylphenyl)-5-oxo-3-propyl-1,5-dihydro-4H-1,2,4-triazol-4-yl]acetamide (22242676) | |||
| ChemBridge特有类药化合物/先导化合物-22242676，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47592 | ChemBridge-22686718 | ChemBridge化合物-22686718 | Screening Compounds and Building Blocks |
| 1-(cycloheptylcarbonyl)-4-(4-cyclohexyl-1H-1,2,3-triazol-1-yl)piperidine (22686718) | |||
| ChemBridge特有类药化合物/先导化合物-22686718，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47689 | ChemBridge-26813786 | ChemBridge化合物-26813786 | Screening Compounds and Building Blocks |
| rel-(1R,5S)-3-[4-(3-hydroxy-3-methylbutyl)benzoyl]-3-azabicyclo[3.1.0]hexane-1,5-dicarboxylic acid (26813786) | |||
| ChemBridge特有类药化合物/先导化合物-26813786，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47719 | ChemBridge-27796026 | ChemBridge化合物-27796026 | Screening Compounds and Building Blocks |
| rel-(1R,5S)-3-[(3-chlorophenoxy)acetyl]-3-azabicyclo[3.1.0]hexane-1,5-dicarboxylic acid (27796026) | |||
| ChemBridge特有类药化合物/先导化合物-27796026，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49189 | ChemBridge-92483526 | ChemBridge化合物-92483526 | Screening Compounds and Building Blocks |
| 6-[(3,5-dimethylisoxazol-4-yl)methyl]-N-[(1R,2R)-2-hydroxycyclohexyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide (92483526) | |||
| ChemBridge特有类药化合物/先导化合物-92483526，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49979 | ChemBridge-24962688 | ChemBridge化合物-24962688 | Screening Compounds and Building Blocks |
| 3-(3-aminopropoxy)-4-methoxy-N-[(3S,7R,8aS)-3-phenylhexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-7-yl]benzamide dihydrochloride (24962688) | |||
| ChemBridge特有类药化合物/先导化合物-24962688，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49992 | ChemBridge-22426220 | ChemBridge化合物-22426220 | Screening Compounds and Building Blocks |
| (2S)-2-amino-2-cyclohexyl-N-{4-[(1-methyl-4-piperidinyl)oxy]phenyl}acetamide dihydrochloride (22426220) | |||
| ChemBridge特有类药化合物/先导化合物-22426220，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M50134 | ChemBridge-8815264 | ChemBridge化合物-8815264 | Screening Compounds and Building Blocks |
| 6-({[(1-methyl-1H-pyrazol-4-yl)methyl]amino}carbonyl)-3-cyclohexene-1-carboxylic acid (8815264) | |||
| ChemBridge特有类药化合物/先导化合物-8815264，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M51308 | Connexin mimetic peptide 40, 37GAP26 | Connexin mimetic peptide 40, 37GAP26 | Others |
| Connexin mimetic peptide 40,37GAP26 是一种有生物活性的肽。 | |||
| M58619 | ALKS 2680 | ALKS 2680 | OX Receptor |
| Alixorexton; ALKS2680 | |||
| ALKS 2680 是一种靶向食欲素2型受体（OX2R）的新型大环化合物，它是OX2R的选择性激动剂。ALKS 2680 具有血脑屏障透过性，它可通过激活 OX2R 来调节动物的睡眠/觉醒周期。此外，ALKS 2680 可用于肥胖症和嗜睡性疾病的研究。 | |||
M5243
|
EED226 | EED226 | PRC2/EED |
| EED226是一种首创（first-in-Class）的，有效的、选择性的、具有口服活性的Polycomb repressive complex 2 (PRC2)抑制剂，以H3K27me0 peptide为底物时，IC50=23.4 nM; 以单核小体为底物时，IC50=53.5 nM。 EED226是具有强大抗癌功效的胚胎外胚层发育(EED)抑制剂。 | |||
| M9042
|
Prexasertib dihydrochloride | Prexasertib dihydrochloride | Checkpoint |
| LY2606368 Prexasertib HCl | |||
| Prexasertib dihydrochloride (LY2606368 HCl) 是一种有效的，ATP竞争性的选择性Chk1抑制剂，对CHK1和CHK2的IC50值分别为 <1 nM 和 8 nM。 | |||
| M9710
|
Roquinimex | Roquinimex | TNF Receptor |
| LS2616; FCF89; Linomide; ABR212616 | |||
| Roquinimex（LS2616; FCF89）是一种免疫刺激剂，具有潜在的抗肿瘤活性，能增强NK细胞活性和巨噬细胞的细胞毒性，并抑制血管生成和TNF α的分泌。 | |||
| M10075
|
(+)-Biotinamidohexanoic acid hydrazide | 生物素LC酰肼 | Others |
| Biotin LC hydrazide | |||
| Biotin LC hydrazide（biotinamido hexanoyl hydrazide，生物素LC酰肼）是一种能产生生物素化标记的化合物。同时也可以非放射性的标记白细胞表面糖蛋白，并能保留CD3和CD26等的免疫原性，能用于双向聚丙烯酰胺凝胶电泳(2D-PAGE)和蛋白质印迹分析（Western Blot）等实验。 | |||
| M13622
|
Prexasertib | 普瑞色替；普赛色替；普沙色替 | Checkpoint |
| LY2606368 | |||
| Prexasertib (LY2606368) 是一种选择性的，ATP 竞争性的第二代细胞周期检测点激酶 1 (CHK1) 抑制剂，Ki 为 0.9 nM，IC50 为 <1 nM。Prexasertib 抑制 CHK2 (IC50=8 nM) 和 RSK1 (IC50=9 nM)。Prexasertib 引起双链 DNA 断裂和复制突变，导致细胞凋亡 (apoptosis)。Prexasertib 显示有效的抗肿瘤活性。 | |||
| M13623 | Prexasertib dimesylate | Prexasertib dimesylate | Checkpoint |
| LY2606368 dimesylate | |||
| Prexasertib dimesylate (LY2606368 dimesylate) 是一种选择性的，ATP 竞争性的第二代细胞周期检测点激酶 1 (CHK1) 抑制剂，Ki 为 0.9 nM，IC50 为 <1 nM。 | |||
| M21413 | Inflexuside B | 英夫赛德B | NO Synthase |
| Inflexuside B 是一种冷杉烷二萜，能够从蛇床子的地上部分分离得到。Inflexuside B 强烈的抑制 RAW264.7 巨噬细胞中脂多糖 LPS 激活的一氧化氮的产生 (NO Synthase)。 | |||
| M27782 | Veledimex | Veledimex | IL Receptor/Related |
| INXN-1001; RG-115932 | |||
| Veledimex (INXN-1001) 是昆虫蜕皮激素蜕皮激素的合成类似物，是一种具有口服活性的用于专有的基因治疗启动子系统的激活配体。Veledimex 可利用蜕皮激素受体 (EcR) 诱导基因调控系统RheoSwitch研究系统 (RTS) 激活某些基因。Veledimex 可透过在原位 GL-261 小鼠和食蟹猴的血脑屏障 (BBB)。 | |||
| M29134 | Azelaprag | Azelaprag | Others |
| AMG 986 | |||
| Azelaprag (Example 263.0) 是一种 apelin受体 激动剂的候选活性分子。 | |||
| M30979 | Dextromilnacipran | 左旋米那普仑 | Serotonin Transporter |
| (1R,2S)-milnacipran; F2696; Levomilnacipran | |||
| Dextromilnacipran (F2696; (1R,2S)-milnacipran) 是米那普仑的对映体，是一种选择性 5- 羟色胺和去甲肾上腺素 (5-HT/NE) 再摄取抑制剂，可用于抑郁的相关研究。Dextromilnacipran 也是一种人类 α 肾上腺素能受体拮抗剂，IC50 为 3.4 μM。 | |||
| M31176
|
Recombinant Human CD40L Protein (E. coli) | 重组人CD40L蛋白 (E. coli) | Cytokines and Growth Factors |
| CD40 Ligand; CD154; TRAP | |||
| CD40 Ligand (CD40L/CD154/TRAP) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. Recombinant Human CD40 Ligand is produced by E.coli expression system and the target gene encoding Met113-Leu261 is expressed. | |||
| M38776 | 1-(26-Hydroxyhexacosanoyl)-glycerol | 1-(26-Hydroxyhexacosanoyl)-glycerol | Parasite |
| 1-(26-Hydroxyhexacosanoyl)-glycerol 是一种有效的抗疟剂。1-(26-Hydroxyhexacosanoyl)-glycerol 具有抗疟活性，对 Plasmodium falciparum 的 IC50 值为 9.48 µM。 | |||
| M40397 | Vitexdoin A | Vitexdoin A | Others |
| Vitexdoin A 是一种清除一氧化氮的木质素。Vitexdoin A 抑制 LPS 刺激的 RAW 264.7 细胞 NO 生成，IC50 为 0.38 μM。 | |||
| M41300 | CDK8-IN-13 | CDK8-IN-13 | Apoptosis |
| CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces Apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity.。 | |||
| M55549
|
Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc) | 重组小鼠DPP-4/CD26 Protein (HEK293, N-hFc) | Cytokines and Growth Factors |
| Dipeptidyl Peptidase 4; DPP IV | |||
| Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). | |||
| M56897 | Flutax-2 | Flutax-2 | Fluorescent Dye |
| Flutax-2 是 Paclitaxel 的活性荧光衍生物，与聚合的 αβ-微管蛋白二聚体结合。Flutax-2 可用于对活细胞、分离的细胞骨架和寄生虫中的微管进行成像 (Ex/Em=496/526 nm)。 | |||
