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 找到约 19 条 “Eact” 相关结果 (用时 0.115 秒)

目录号 产品名称 中文名称 靶点
M6695 Eact Eact Chloride Channel
Eact是一种 Ca2+-激活的Cl- 通道跨膜蛋白16A (TMEM16A)的激活剂,EC50值为3.92±0.87 μM。
M51617 C-Reactive Protein (CRP) (77-82) C-Reactive Protein (CRP) (77-82) Others
C-Reactive Protein (CRP) 77-82 是 C-反应蛋白的 77-82 片段。
M51626 C-Reactive Protein (CRP) (201-206) C-Reactive Protein (CRP) (201-206) Others
C-Reactive Protein (CRP) 201-206 是 C-反应蛋白的 201-206 片段。
M53960 C-Reactive Protein (CRP) (174-185) C-Reactive Protein (CRP) (174-185) Others
C-Reactive Protein (CRP) 174-185 是 C-反应蛋白的 174-185 片段。
M8262 HI-6 HI-6 Others
HI-6 is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure.
M8427 MMB-4 MMB-4 Others
MMB-4 is an oxime that can reactivate cholinesterases that have been inactivated by exposure to organophosphates such as sarin or soman.
M8451 SW155246 SW155246 Others
SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor that demethylates cytosines in vivo in a cell-based assay without affecting protein levels or generating reactive oxygen species.
M19923 KKL-35 KKL-35 Antibiotic
KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity.
M20085 WAY-320049 WAY-320049 Others
WAY-320049 can modulate mitochondrial reactive oxygen species production
M20457 Pralidoxime Iodide Pralidoxime Iodide AChR/AChE
2-PAM
Pralidoxime Iodide (2-PAM) is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.
M20485 Phenylglyoxal hydrate Phenylglyoxal hydrate Dehydrogenase
1-Phenylethanedione hydrate
Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.
M20734 (E/Z)-BCI (E/Z)-BCI Phosphatase
BCI, NSC 150117
(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
M20902 Pyridoxal 5-phosphate monohydrate Pyridoxal 5-phosphate monohydrate Vitamin
Pyridoxal 5-phosphate monohydrate is an active vitamin B6 metabolite, which is a cofactor in many reactions of amino acid metabolism.
M20917 Pyridoxal phosphate Pyridoxal phosphate Vitamin
pyridoxal 5'-phosphate, PAL-P, PLP, Vitamin B6 phosphate
Pyridoxal phosphate, the active form of vitamin B6, acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.
M21009 L-Ornithine hydrochloride L-Ornithine hydrochloride Others
(S)-2,5-Diaminopentanoic acid
L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.
M21349 Phycocyanobilin 螺旋藻;藻蓝素 ROS
Phycocyanobilin (螺旋藻,藻蓝素) 是一种具有口服活性的抗氧化剂 (reactive oxygen species),同时也是 有效的活性氧清除剂。可用于阿尔茨海默病的研究。
M30931 IA-Alkyne IA-Alkyne TRP Channel
Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) 是一种 TRP 通道 (TRPC) 的激动剂,有潜力用于呼吸道感染相关疾病的研究。IA-Alkyne 可以用来开发同位素标记的探针,用于定量的半胱氨酸反应分析 (cysteine-reactivity)。
M45003 Selaginellin 垫状卷柏三酚 ROS
Selaginellin 是 Reactive Oxygen Species 的抑制剂和 SIRT1 的激活剂。
M54827 Farnesyl S-Thiolodiphosphate Farnesyl S-Thiolodiphosphate Others
FSPP
Farnesyl thiolodiphosphate (FSPP) is an analog of FPP in which the non-bridging oxygen has been replaced by sulfur resulting in a less-reactive compound.









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