找到约 54 条 “Choline” 相关结果 （用时 0.113 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M13353
|
Phosphatidylcholines,soya | 大豆磷脂酰胆碱 | Liposome |
| Soybean phosphatidylcholine | |||
| Phosphatidylcholines,soya （大豆磷脂酰胆碱）是一种从大豆中提取的磷脂酰胆碱，可用于脂质体的制备。已被证明在许多重要领域发挥重要作用，包括维持细胞结构，脂肪代谢，记忆，神经信号和作为重要神经递质的前体等。Phosphatidylcholines,soya 还可作为动物给药的载体。 | |||
| M2517
|
Choline Chloride | 氯化胆碱 | AChR/AChE |
| Choline Chloride是一种季铵盐，作为动物饲料添加剂。 | |||
| M2853
|
Miltefosine | 米替福新 | Akt |
| Hexadecylphosphocholine | |||
| Miltefosine（米替福新）作用于癌细胞系A431和HeLa，抑制PI3K/Akt活性，ED50分别为17.2 μM和8.1 μM，具有口服活性，有效对抗前鞭毛体和无鞭毛体。 | |||
| M3034
|
Succinylcholine Chloride Dihydrate | 司可林 | AChR/AChE |
| Suxamethonium Chloride Dihydrate | |||
| Succinylcholine Chloride Dihydrate是一种烟碱AChR激动剂，同时也是一种去极化神经肌肉阻断剂。 | |||
| M3163
|
Phosphatidylcholine | 卵磷脂 | Others |
| PC | |||
| Phosphatidylcholine（磷脂酰胆碱，卵磷脂）是细胞膜和肺表面活性物质的主要成分，通常存在于细胞膜的外质或外叶中。 | |||
| M3309
|
Bethanechol chloride | 氯贝胆碱 | AChR/AChE |
| Carbamyl-β-methylcholine chloride | |||
| Bethanechol chloride是一种选择性毒蕈碱受体激动剂，对烟碱受体没有任何效果。 | |||
| M3317
|
Acetylcholine Chloride | 氯化乙酰胆碱 | AChR/AChE |
| Ach; ACh chloride | |||
| Acetylcholine chloride (ACh chloride) 是一种神经递质，是一种有效的胆碱能 (cholinergic) 激动剂。Acetylcholine chloride 是通过刺激烟碱乙酰胆碱受体 (nAChRs) 调节多巴胺能 (DAergic) 神经元活性，作用于包括人类在内的许多生物的周围神经系统（PNS）和中枢神经系统（CNS）。 | |||
| M5776
|
Methacholine chloride | 氯化乙酰甲胆碱 | AChR/AChE |
| Acetyl-β-methylcholine chloride | |||
| Methacholine chloride是选择性毒蕈碱受体mAChR激动剂。 | |||
| M6680
|
DLPC | DLPC | Liposome |
| 1,2-Dilauroyl-sn-glycero-3-phosphocholine | |||
| DLPC是LRH-1 受体的选择性激动剂。同时也是一种磷脂，可用于脂质体的合成。 | |||
| M7679 | Acetylethylcholine mustard hydrochloride | Acetylethylcholine mustard hydrochloride | Others |
| Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase. | |||
| M7696
|
Choline bitartrate | 酒石酸氢胆碱；重酒石酸胆碱 | Others |
| Acyl group acceptor. | |||
| M10119
|
DOPC | 1,2-二油酰基-sn-甘油-3-磷酸胆碱 | Cell Transfection |
| 1,2-Dioleoyl-sn-glycero-3-phosphocholine | |||
| 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC)是一种磷脂，在胶束，脂质体和其他类型的人工膜的生成中通常单独或与其他组分一起使用。能用于药物递送的相关研究。 | |||
| M10121
|
DSPC | 二硬脂酰磷脂酰胆碱；1,2-二硬脂酰-sn-甘油-3-磷酸胆碱 | Cell Transfection |
| 1,2-Distearoyl-sn-glycero-3-phosphocholine | |||
| 1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC，二硬脂酰磷脂酰胆碱) 是一种磷脂，由磷脂酰胆碱头部基团和两个饱和的18碳尾部组成，两个尾巴形成紧密堆积的脂质双层。DSPC能合成脂质体和脂质纳米颗粒 (LNP) 系统，可用于mRNA疫苗的药物输送系统的相关研究。 | |||
| M10154
|
Choline Glycerophosphate | 甘油磷酸胆碱 | AChR/AChE |
| Choline Alfoscerate | |||
| Choline Glycerophosphate甘油磷酸胆碱是脑磷脂生物合成的前体，可提高胆碱在神经组织中的生物利用度。 | |||
| M10447
|
DMPC | DMPC | Cell Transfection |
| 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine | |||
| DMPC(1,2-Dimyristoyl-sn-glycero-3-phosphocholine，Dimyristoyl phosphatidylcholine, 二肉豆蔻酰基卵磷脂) 是一种用于生物膜研究的脂质体和脂质双层中的合成磷脂。经研究发现，加入DMPC可以显著抑制Carmofur在中性磷酸盐缓冲溶液中的降解，并增强Carmofur抗肿瘤细胞生长的能力，可以进行药物递送的相关研究。 | |||
| M14400 | Phosphorylcholine | 磷酸胆碱 | Metabolite/Endogenous Metabolite |
| Phosphocholine | |||
| Phosphorylcholine 是真核生物膜中的主要磷脂组分，在原核生物中存在于那些与真核生物相关联的共生菌或致病菌中。Phosphorylcholine 具有免疫调节特性。 | |||
| M14753
|
Phosphorylcholine chloride | Phosphorylcholine chloride | Others |
| Phosphocholine chloride | |||
| Phosphorylcholine chloride (Phosphocholine chloride) 是构成细胞膜外层结构卵磷脂的组成成分，具有良好的血液相容性。 | |||
| M14955
|
Acetylcholine iodide | 碘化乙酰胆碱 | Others |
| ACh iodide | |||
| Acetylcholine iodide (ACh iodide) 是一种 muscarinic receptor 调节剂。 | |||
| M18146
|
Egg yolk phosphatidylcholines | 蛋黄磷脂酰胆碱 | Others |
| Lecithins, egg 可用作药用辅料。 | |||
| M20809 | ADH-503 (GB1275) | ADH-503 (GB1275) | Others |
| (Z)-Leukadherin-1 choline | |||
| ADH-503 (GB1275, (Z)-Leukadherin-1 choline) is the salt form of leukadherin-1 and acts as a potent allosteric agonist of CD11b. | |||
| M20942 | Choline Fenofibrate | Choline Fenofibrate | PPAR |
| Choline fenofibrate is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist. | |||
| M21006 | Citicoline sodium | Citicoline sodium | Others |
| CDP-choline | |||
| Citicoline is an essential intermediate in the synthesis of the major phospholipid of the cell membranes, phosphatidylcholine (PtdCho). It increases plasma adrenocorticotropic hormone (ACTH) levels and potentiates serum thyrotrophin (TSH) levels by activating the central cholinergic system. | |||
| M22418
|
Calcium phosphorylcholine chloride | 氯化磷酰胆碱钙盐 | Metabolite/Endogenous Metabolite |
| Calcium phosphorylcholine chloride（氯化磷酰胆碱钙盐）是phosphorylcholine chloride的钙盐形式。此外，phosphorylcholine chloride也是一种内源代谢物。 | |||
| M25504
|
1,2-Dierucoyl-sn-glycero-3-phosphocholine | 1,2-Dierucoyl-sn-glycero-3-phosphocholine | Cell Transfection |
| DEPC; L-Dierucoyl lecithin; Dierucoyllecithin | |||
| 1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) 是脂质体膜的组成成分。1,2-Dierucoyl-sn-glycero-3-phosphocholine 被用来制备脂质体和研究脂质双分子层。1,2-Dierucoyl-sn-glycero-3-phosphocholine 脂质体中的 GO （葡萄糖氧化酶） 显示出高活性。 | |||
| M27807 | Propargylcholine bromide | Propargylcholine bromide | Others |
| Propargylcholine bromide 是一种含有末端炔丙基的胆碱类似物，可掺入所有类别 (如磷脂酰胆碱和鞘磷脂) 的胆碱磷脂 (含有胆碱的磷脂) 中，对胆碱磷脂进行标记。Propargylcholine bromide 标记的磷脂分子可以在细胞中以高灵敏度和空间分辨率进行可视化。Propargylcholine bromide 可作为分子工具，在细胞内对胆碱磷脂的生化和代谢过程进行研究。 | |||
| M29854 | Dodecylphosphocholine | Dodecylphosphocholine | Others |
| Dodecylphosphocholine 是一种广泛用于膜蛋白核磁共振 (NMR) 研究的去污剂。 | |||
| M30986
|
Citicoline | 胞磷胆碱 | Apoptosis |
| Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine | |||
| Citicoline (Cytidine diphosphate-choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体。发挥神经保护作用。 | |||
| M39080 | Lysophosphatidylcholine 18:2 | Lysophosphatidylcholine 18:2 | Metabolite/Endogenous Metabolite |
| Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC)，一种溶血磷脂，是一种从胰岛素抵抗 (IR) 多囊卵巢综合征 (PCOS) 中发现的潜在生物标志物。低血浆 Lysophosphatidylcholine 18:2 还可以预测糖耐量受损、胰岛素抵抗、2 型糖尿病、冠心病和记忆障碍。 | |||
| M39690
|
1-Stearoyl-sn-glycero-3-phosphocholine | 1-Stearoyl-sn-glycero-3-phosphocholine | Others |
| 18:0 Lyso PC; PC(18:0/0:0) | |||
| 1-Stearoyl-sn-glycero-3-phosphocholine 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M39735
|
Chlorocholine chloride | 矮壮素 | Others |
| Chlorocholine chloride 是一种有效的植物生长调节剂。Chlorocholine chloride 可抑制赤霉素 (GA) 的生物合成。 | |||
| M2441
|
Benzethonium Chloride | 苄索氯铵 | AChR/AChE |
| Benzethonium Chloride是一种有效的neuronal nicotinic acetylcholine receptors (nAChRs)（神经元烟碱型乙酰胆碱受体）抑制剂，抑制α4β2 nAChRs和α7 nAChRs，IC50分别为49 nM和122 nM。 | |||
| M2636
|
Dicyclomine hydrochloride | 盐酸双环维林 | AChR/AChE |
| Dicycloverine HCl | |||
| Dicyclomine is an anticholinergic drug, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). | |||
| M2939
|
Physostigmine Salicylate | 水杨酸毒扁豆碱 | AChR/AChE |
| Eserine Salicylate | |||
| Physostigmine is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. | |||
| M2947
|
Pipenzolate Bromide | 溴哌喷酯 | AChR/AChE |
| Pipenzolate is an antimuscarinic, which binds to muscarinic receptors as an antagonist therefore preventing acetyl choline from binding to the receptors. | |||
| M2957
|
Pridinol Methanesulfonate | Pridinol Methanesulfonate | AChR/AChE |
| Pridinol Methanesulfonate Salt is used as an anticholinergic and as an antiparkinsonian agent. | |||
| M3253
|
(-)-Huperzine A | 石杉碱甲 | AChR/AChE |
| (-)-Huperzine A (HupA)是一种有效的，高度特异性的，可逆acetylcholinesterase (AChE)（乙酰胆碱酯酶）抑制剂，Ki为7 nM，作用于G4 AChE比作用于G1 AChE选择性高200倍。(-)-Huperzine A 也是 N-甲基-D-天冬氨酸 (NMDA) 受体的非竞争性拮抗剂。 | |||
| M1364
|
1-Benzyl-1H-indole-2,3-dione | 1-苄基-1H-吲哚-2,3-二酮 | AChR/AChE |
| 1-Benzyl-1H-indole-2,3-dione（1-苄基-1H-吲哚-2,3-二酮），可作用于CHRM1 - 胆碱能受体毒蕈碱1（CHRM1 - cholinergic receptor muscarinic 1），EC50为0.01μM。抑制人ALDH1A1 ，IC50为0.01μM。 | |||
| M6670 | Dianicline | Dianicline | Others |
| Dianicline是一种选择性的 α4β2 烟碱型乙酰胆碱受体 (nicotinic acetylcholine receptor) 部分激动剂。 | |||
| M7134 | Phenserine | Phenserine | Others |
| Phenserine is a cholinesterase inhibitor. | |||
| M7309 | SM-21 maleate | SM-21 maleate | Others |
| SM-21 maleate is a presynaptic cholinergic modulator. | |||
| M11370
|
Recombinant Human LIF Protein (E.coli) | 重组人LIF蛋白 (E.coli) | Cytokines and Growth Factors |
| Leukemia Inhibitory Factor; LIF; Differentiation-Stimulating Factor | |||
| Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. | |||
| M7589 | Arecaidine propargyl ester hydrobromide | Arecaidine propargyl ester hydrobromide | Others |
| Potent muscarinic acetylcholine receptor agonist exhibiting slight selectivity for M2 receptors; inactive at nicotinic receptors. | |||
| M7599 | ABT-418 hydrochloride | ABT-418 hydrochloride | Others |
| Neuronal nicotinic acetylcholine receptor agonist with cognition enhancing and anxiolytic activities. | |||
| M7774 | DBO-83 | DBO-83 | Others |
| Novel nicotinic acetylcholine receptor agonist, structurally related to epibatidine, with antinociceptive properties in rodents. | |||
| M7788 | Ethopropazine hydrochloride | 盐酸乙丙嗪；爱普把嗪；盐酸普罗芬胺 | Others |
| Ethoproprazine hydrochloride is an inhibitor of butyrylcholinesterase; antiparkinsonian. | |||
| M7853
|
Ipratropium bromide monohydrate | 异丙托溴铵一水合物 | AChR/AChE |
| Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator. | |||
| M7854 | Ilmofosine | Ilmofosine | Others |
| Protein Kinase C (PKC) inhibitor; an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. | |||
| M7933 | (+)-Muscarine chloride | (+)-Muscarine chloride | Others |
| Prototype muscarinic acetylcholine receptor agonist; active enantiomer. | |||
| M7940
|
Mecamylamine hydrochloride | 盐酸美加明 | AChR/AChE |
| Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier. | |||
| M7976 | Oxotremorine M | Oxotremorine M | Others |
| Nonselective muscarinic acetylcholine receptor agonist. | |||
| M8262
|
HI-6 | HI-6 | Others |
| HI-6 is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure. | |||
| M8266 | ML169 | ML169 | Others |
| ML169 is a positive allosteric modulator (PAM) of the muscurinic acetycholine receptor M1 (CHRM1). | |||
| M8269 | 4-DAMP | 4-DAMP | AChR/AChE |
| 4-DAMP methiodide | |||
| 4-DAMP是一种选择性M3型毒蕈碱乙酰胆碱受体（Muscarinic Acetylcholine Receptor，mAChR）拮抗剂，它同时对M1受体也有一定的结合能力。4-DAMP通过选择性阻断M3受体，抑制乙酰胆碱介导的信号传导，它主要用于研究胆碱能信号通路、受体功能分析及神经退行性疾病模型。 | |||
| M8282 | Deformylflustrabromine hydrochloride | Deformylflustrabromine hydrochloride | Others |
| Deformylflustrabromine hydrochloride; dFBr hydrochloride | |||
| Desformylflustrabromine (dFBr) is a potent, selective positive allosteric modulator of α4β2 nicotinic receptor; increases efficacy and potency of acetylcholine. | |||
