找到约 21 条 “Aurora Kinase” 相关结果 （用时 0.326 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M3931
|
Aurora Kinase Inhibitor III | Aurora Kinase Inhibitor III | Aurora Kinase |
| Aurora Kinase Inhibitor 3 | |||
| Aurora Kinase Inhibitor III是一种有效的，选择性 Aurora A 激酶抑制剂，IC50 为 42 nM。 | |||
| M29284 | Aurora kinase inhibitor-8 | Aurora kinase inhibitor-8 | Aurora Kinase |
| Aurora kinase inhibitor-8 是一种高选择性 Aurora 激酶的抑制剂。 | |||
| M29927 | Aurora kinase inhibitor-2 | Aurora kinase inhibitor-2 | Aurora Kinase |
| Aurora kinase inhibitor-2 是一种选择性和 ATP 竞争性的 Aurora 激酶抑制剂，对 Aurora A 和 Aurora B 的 IC50 分别为 310 nM 和 240 nM。 | |||
| M41412 | Aurora Kinases-IN-4 | Aurora Kinases-IN-4 | Aurora Kinase |
| Aurora Kinases-IN-4 是一种共价 ATP 竞争性 aurora kinase A 抑制剂 (IC50: 1.7 nM)。 | |||
| M1769
|
PHA-739358 (Danusertib) | 达那色替 | Aurora Kinase |
| Danusertib | |||
| Danusertib (PHA-739358)是一种Aurora kinase抑制剂，作用于Aurora A/B/C时IC50为13 nM/79 nM/61 nM，适度有效作用于Abl， TrkA， c-RET和FGFR1，对Lck， VEGFR2/3， c-Kit， CDK2等作用效果稍弱。 | |||
| M2169
|
AMG 900 | AMG 900 | Aurora Kinase |
| AMG-900是一种有效的，高选择性的pan-Aurora kinases抑制剂，作用于Aurora A/B/C，IC50为5 nM/4 nM/1 nM，作用于Aurora激酶比作用于p38α， Tyk2， JNK2， Met和Tie2选择性高10倍以上。 | |||
| M5236
|
BI-847325 | BI-847325 | MEK |
| BI-847325是一种口服具有生物活性的选择性的双重MEK/Aurora kinase抑制剂，对非洲爪蟾Aurora B，人Aurora A 和Aurora C，以及人MEK1 和MEK2的IC50分别为3 nM，25 nM，15 nM，25 nM，和4 nM。 | |||
| M7363 | TC-A 2317 hydrochloride | TC-A 2317 hydrochloride | Others |
| TC-A 2317 hydrochloride is a potent, selective Aurora kinase A inhibitor. | |||
| M7393 | TC-S 7010 | TC-S 7010 | Others |
| TC-S 7010 is a potent and selective Aurora kinase A inhibitor. | |||
| M7986 | OM137 | OM137 | Others |
| OM137 is an inhibitor of aurora kinases; inhibitor of spindle checkpoint. | |||
| M8042
|
CP-335963 | CP-335963 | Others |
| CP-335963 is an aurora 2 kinase inhibitor, PDGF inhibitor, and anti-proliferative. | |||
| M9895
|
LY3295668 | LY3295668 | Aurora Kinase |
| AK-01 | |||
| LY3295668（AK-01）是一种有效的，具有口服活性的Aurora A kinase抑制剂，它对AURA和AURB的Ki值分别为0.8 nM和1038 nM。 | |||
| M13591 | Cenisertib | Cenisertib | Aurora Kinase |
| AS-703569; R-763 | |||
| Cenisertib (AS-703569) 是一种 ATP 竞争性的多激酶抑制剂，可抑制 Aurora-kinase-A/B，ABL1，AKT，STAT5, FLT3 的活性。Cenisertib 通过抑制肿瘤肥大细胞 (MC) 中几种不同分子靶标的活性抑制其生长。Cenisertib 抑制异种移植模型中胰腺癌，乳腺癌，结肠癌，卵巢癌和肺癌以及白血病的肿瘤生长。 | |||
| M20235 | WAY-632963 | WAY-632963 | Aurora Kinase |
| WAY-632963 is a Aurora kinase A inhibitor. | |||
| M20238 | WAY-634704 | WAY-634704 | Aurora Kinase |
| WAY-634704 is a Aurora kinase A inhibitor. | |||
| M20244 | WAY-635764 | WAY-635764 | Aurora Kinase |
| WAY-635764 is a Aurora kinase A inhibitor. | |||
| M20245 | WAY-635767 | WAY-635767 | Aurora Kinase |
| WAY-635767 is a Aurora kinase A inhibitor | |||
| M20246 | WAY-636900 | WAY-636900 | Aurora Kinase |
| WAY-636900 is a Aurora kinase A inhibitor. | |||
| M20247 | WAY-636982 | WAY-636982 | Aurora Kinase |
| WAY-636982 is a Aurora kinase A inhibitor. | |||
| M20251 | WAY-638641 | WAY-638641 | Aurora Kinase |
| WAY-638641 is a Aurora kinase A inhibitor. | |||
| M20284 | WAY-661516 | WAY-661516 | Aurora Kinase |
| WAY-661516 is a Aurora kinase A inhibitor. | |||
