找到约 6 条 “ACV1” 相关结果 （用时 0.113 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M24696 | Ascrinvacumab | Ascrinvacumab | ALK |
| Anti-ACVRL1/ALK-1 Reference Antibody; PF-03446962 | |||
| Ascrinvacumab (PF-03446962) 是一种人 IgG2 单克隆抗体，靶向 ALK-1。Ascrinvacumab 显示出与人 ALK1 的结合效能，Kd 值为 7 nM。Ascrinvacumab 可用于肝细胞癌 (HCC) 的研究。 | |||
| M52755 | ACV1 | ACV1 | AChR/AChE |
| ACV1 (Vc1.1) 是一种 α-芋螺毒素，是一种选择性 α9α10 nAChR 拮抗剂，IC50 为 19 nM。 | |||
M1700
|
Momelotinib (CYT387) | 莫罗替尼 | JAK |
| LM-1149; Momelotinib; CYT 11387 | |||
| Momelotinib (CYT387)是一种ATP竞争性JAK1/JAK2抑制剂，IC50为11 nM/18 nM，比作用于JAK3选择性约高10倍左右。此外，Momelotinib还是激活素A受体I型（ACVR1）的抑制剂。可用于骨髓纤维化的相关研究。 | |||
| M13852 | Momelotinib sulfate | Momelotinib sulfate | JAK |
| CYT387 sulfate salt | |||
| Momelotinib sulfate (CYT387 sulfate salt) 是一种 ATP竞争性的 JAK1/JAK2 抑制剂，IC50 分别为 11 nM/18 nM，作用于JAK3时，IC50 为 155 nM。此外，Momelotinib还是激活素A受体I型（ACVR1）的抑制剂。可用于骨髓纤维化的相关研究。 | |||
| M49566 | Itacnosertib | Itacnosertib | JAK |
| Itacnosertib (TP-0184) 是JAK2，ACVR1 (ALK2)和ALK5的抑制剂。 | |||
| M55353
|
Recombinant Human BMP-9 Protein (E. coli, His Tag) | 重组人BMP-9 蛋白 (E. coli, His Tag) | Cytokines and Growth Factors |
| Bone Morphogenetic Protein-9; GDF-2 | |||
| Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1. | |||
