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Recombinant Mouse MMP-2 Protein (HEK293, N-His) 重组小鼠MMP-2蛋白 (HEK293, N-His)

目录号 M31128 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Matrix Metalloproteinase-2 (MMP-2) is an enzyme that plays a pivotal role in cell migration during physiological and pathological processes. The recombinant mouse MMP-2 consists 273 amino acids and predicts a molecular mass of 30.9 kDa.

Recombinant Mouse MMP-2 Protein (HEK293, N-His)结构式

别名:Matrix Metalloproteinase-2

规格 价格 库存状态
20ug ¥ 4995 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

Matrix Metalloproteinase-2 (MMP-2) is an enzyme that plays a pivotal role in cell migration during physiological and pathological processes. The recombinant mouse MMP-2 consists 273 amino acids and predicts a molecular mass of 30.9 kDa.

MMP-2 is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, atherosclerotic plaque rupture, as well as degrading extracellular matrix proteins. MMP-2 cleaves KISS at a Gly-|-Leu bond and appears to have a role in myocardial cell death pathways. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction.

A DNA sequence encoding the mouse Mmp2 (NP_032636.1) (Met409-Cys662) was expressed with a polyhistidine tag at the N-terminus.


Endotoxin < 1 EU/µg

Lyophilized from sterile PBS, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml.
储存条件 Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Yixuan Ma, et al. Int J Mol Sci. Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction

[2] Shoujun Bai, et al. Cell Death Dis. Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis

[3] Jian Xu, et al. Pharmacol Res. Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy

[4] Angélica M Amanso, et al. Arterioscler Thromb Vasc Biol. Polymerase δ-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb

[5] Diego Sbardella, et al. IUBMB Life. Enzymatic processing by MMP-2 and MMP-9 of wild-type and mutated mouse β-dystroglycan

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