Matrix Metalloproteinase-2 (MMP-2) is an enzyme that plays a pivotal role in cell migration during physiological and pathological processes. The recombinant mouse MMP-2 consists 273 amino acids and predicts a molecular mass of 30.9 kDa.
别名:Matrix Metalloproteinase-2
Matrix Metalloproteinase-2 (MMP-2) is an enzyme that plays a pivotal role in cell migration during physiological and pathological processes. The recombinant mouse MMP-2 consists 273 amino acids and predicts a molecular mass of 30.9 kDa.
MMP-2 is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, atherosclerotic plaque rupture, as well as degrading extracellular matrix proteins. MMP-2 cleaves KISS at a Gly-|-Leu bond and appears to have a role in myocardial cell death pathways. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction.
A DNA sequence encoding the mouse Mmp2 (NP_032636.1) (Met409-Cys662) was expressed with a polyhistidine tag at the N-terminus.
Endotoxin < 1 EU/µg
Lyophilized from sterile PBS, pH 7.4.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
储存条件 | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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