重组人IFN-β蛋白(HEK 293)通过STAT1和STAT2发挥作用,已知可上调和下调多种基因,其中大多数参与抗病毒免疫应答。蛋白构造:IFN-β (Met22-Asn187) ,Accession # P01574。
表达系统:HEK 293
纯度:SDS-PAGE分析,> 95%
内毒素:凝胶凝血法测定蛋白质< 0.2 EU/μg
表观分子量:~23 kDa,还原条件下在SDS-PAGE上
存储及稳定性:在接收后,该产品在低于-70°C的环境下保持稳定长达6个月。重组后,产品应在4°C下稳定1周或在-20°C下稳定3个月。为了长期保存,建议添加载体蛋白(如0.1% BSA)。避免反复的冻融循环。
生物活性:干扰素β (IFN-β)通过STAT1和STAT2发挥作用,已知可上调和下调多种基因,其中大多数参与抗病毒免疫应答。它是I型干扰素的成员,I型干扰素包括IFN-α、-β、τ和-ω。IFN-β在诱导对广泛的病毒感染的非特异性耐药性中发挥重要作用。它还影响细胞增殖和调节免疫反应。
储存条件 |
粉末型式 -20°C 3年;4°C 2年 溶于溶剂 -80°C 6个月;-20°C 1个月 |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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