Cycloheximide  别名：Naramycin A; Actidione; CHX; FT 3422-2; NM-MCD 80; 放线菌酮

iScience. 2024 May 15.

Deficiency in Prader-Willi syndrome gene necdin leads to attenuated cardiac contractility

PLoS Pathog. 2024 Sep 30;20(9):e1012594.

TRIM56 restricts Coxsackievirus B infection by mediating the ubiquitination of viral RNA-dependent RNA polymerase 3D

J Biol Chem. 2024 Mar 25;300(5):107226.

Epstein-Barr virus suppresses N6-Methyladenosine modification of TLR9 to promote immune evasion

Cell Signal. 2024 May 26;111235.

BMSC derived EVs inhibit colorectal Cancer progression by transporting MAGI2-AS3 or something similar

Respir Res. 2024 Jul 25;25(1):287.

Novel hypoxia-induced HIF-1αactivation in asthma pathogenesis

Mol Carcinog. 2024 Jan.

SN-38, an active metabolite of irinotecan, inhibits transcription of nuclear factor erythroid 2-related factor 2 and enhances drug sensitivity of colorectal cancer cells

iScience. 2024 Jan 19.

FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression

Mol Cell Biochem. 2024 Feb 17.

Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling

Sci Rep. 2024 Oct 10;14(1):23685.

USP10 promotes cell proliferation, migration, and invasion in NSCLC through deubiquitination and stabilization of EIF4G1

Viruses. 2024 Sep 23;16(9):1503.

N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1

Leuk Res. 2024 Jun 29;52(1):46.

Combining the novel FLT3 and MERTK dual inhibitor MRX-2843 with venetoclax results in promising antileukemic activity against FLT3-ITD AML

Patent. CN117535410A 2024 Feb 09.

Patent. CN117535410A

J Transl Med. 2023 May 5;21(1):303.

SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion

Cell Death Discov. 2023 Apr 26.

Ammonium Tetrathiomolybdate Relieves Oxidative Stress in Cisplatin-induced Acute Kidney Injury via NRF2 Signaling Pathway

Cell Death Discov. 2023 Jul 25;9(1):259.

Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway

J Cell Mol Med. 2023 Aug 29.

Alleviation of temporomandibular joint osteoarthritis by targeting RIPK1-mediated inflammatory signalling

FASEB J. 2023 Oct;37(10):e23183.

IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner

New Journal of Chemistry. 2023 Jun 20.

Quantitative analysis of the effects of vimentin intermediate filaments on the early stages of influenza A virus infection

New J. Chem. 2023 Jun 28;47, 14344-14354.

Quantitative analysis of the effects of vimentin intermediate filaments on the early stages of influenza A virus infection

Biochem Genet. 2023 Nov 11.

Functional Characterization of a Novel SLC4A4 Variant and Uniparental Isodisomy in Proximal Renal Tubular Acidosis Patient

Cell Death Differ. 2022 Jul;29(7):1395-1408.

SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK

Research Square. 2022 Oct 12.

IGF2BP2 promotes ovarian cancer growth and metastasis via upregulating CKAP2L protein expression in a m6A-dependent manner

Ecotoxicol Environ Saf. 2022 Jun 1;237:113564.

Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop

Virol Sin. 2022 Aug 16;S1995-820X(22)00143-2.

CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells

Cell Biol Toxicol. 2022 Apr;38(2):291-310.

Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage

Bioengineered. 2022 Apr;13(4):8000-8012.

UBE2B promotes ovarian cancer growth via promoting RAD18 mediated ZMYM2 monoubiquitination and stabilization

J Biol Chem. 2022 Nov 21;102734.

Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer

Mol Cell Endocrinol. 2022 Apr 5;545:111575.

An intron mutation of HNF1A causes abnormal splicing and impairs its activity as a transcription factor

Adv Sci (Weinh). 2021 Feb.

Inhibition Lysosomal Degradation of Clusterin by Protein Kinase D3 Promotes Triple‐Negative Breast Cancer Tumor Growth

Adv Sci (Weinh). 2021 Jan 6;8(4):2003205.

Inhibition Lysosomal Degradation of Clusterin by Protein Kinase D3 Promotes Triple-Negative Breast Cancer Tumor Growth

Clin Transl Med. 2021 Apr;11(4):e395.

FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression

Int J Mol Sci. 2021 Aug 16;22(16):8779.

Autophagy Mediates the Degradation of Plant ESCRT Component FREE1 in Response to Iron Deficiency

J Cancer. 2021 Oct 17;12(23):7041-7051.

N6-methyladenosine regulates ATM expression and downstream signaling

Cell Rep. 2020 Jul 28;32(4):107974.

L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis

Cell Rep. 2020 Jul 28;32(4):107974.

LARP7 is a BRCA1 ubiquitinase substrate and regulates genome stability and tumorigenesis

Theranostics. 2020 Apr 27;10(13):5671-5686.

SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma

Cell Oncol (Dordr). 2020 Oct 19.

Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A

Cell Microbiol. 2020 Mar;22(3):e13148.

Hepatitis B virus X protein modulates upregulation of DHX9 to promote viral DNA replication.

Life Sci. 2020 Sep 15;257:118021.

TRIB3 destabilizes tumor suppressor PPARα expression through ubiquitin-mediated proteasome degradation in acute myeloid leukemia

Front Cell Infect Microbiol. 2020 Apr 16;10:158.

Difluoromethylornithine, a Decarboxylase 1 Inhibitor, Suppresses Hepatitis B Virus Replication by Reducing HBc Protein Levels

Aging (Albany NY). 2018 Oct 18;10(10):2783-2799.

Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-β signaling-induced epithelial-mesenchymal transition.

Biotechnol Lett. 2018 Aug;40:1181-1188.

UHRF2 promotes DNA damage response by decreasing p21 via RING finger domain.

Protein Cell. 2017 Mar;8(3):202-218.

E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain