M2628
|
Dexmedetomidine |
Dexmedetomidine（右美托嘧啶）是一种咪唑衍生物，同时也是Medetomidine的活性d-异构体形式。此外，Dexmedetomidine也是有效的，高选择性的α2肾上腺素受体（α2-AR）激动剂，可以抑制突触小泡释放去甲肾上腺素。 |
| M3057
|
Terbutaline Sulfate |
Terbutaline Sulfate是一种选择性的β2-肾上腺素能受体激动剂，IC50为53 nM。 |
| M3752
|
Phentolamine Mesylate |
Phentolamine Mesylate（甲磺酸酚妥拉明，酚胺唑啉马来酸盐）是Phentolamine的甲磺酸盐形式，同时也是一种非选择性的α1和α2肾上腺素受体（α1-AR/α2-AR）拮抗剂。 |
| M2420
|
Labetalol hydrochloride |
Labetalol hydrochloride是一种选择性alpha1-adrenergic 和非选择性beta-adrenergic receptors的双重拮抗剂。 |
| M13893
|
Labetalol |
Labetalol (AH5158) 是一种具有口服活性的选择性 α1- 和非选择性 β-肾上腺素能受体 (adrenergic receptor) 竞争性拮抗剂。Labetalol 是一种抗高血压药物，可用于心血管疾病的研究，如妊娠期高血压。 |
| M20937
|
Midodrine hydrochloride |
Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor. |
| M20936
|
Isoproterenol sulfate dihydrate |
Isoproterenol sulfate dihydrate是一种非选择性的β-肾上腺受体激动剂，可用于心力衰竭和哮喘等疾病的相关研究。 |
| M20883
|
3-Nitro-L-tyrosine |
3-Nitro-L-tyrosine (3-NT, N-Tyr, MNT), synthesized from L-tyrosine by peroxynitrite, is a product of nitric oxide and superoxide. 3-Nitro-L-tyrosine inhibits the hemodynamic responses to angiotensin II, possibly through the inhibition of alpha 1-adrenoceptor-mediated events. |
| M20572
|
Carazolol |
Carazolol is a non-specific β-adrenergic receptor blocking agent and binds to β receptors irreversibly. |
| M20553
|
Celiprolol hydrochloride |
Celiprolol is a β1-adrenoceptor antagonist with partial β2 agonist activity. |
| M20538
|
Doxazosin |
Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. |
| M20537
|
Esmolol |
Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages. |
| M20519
|
Moxisylyte hydrochloride |
Moxisylyte hydrochloride is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease. |
| M20504
|
Tizanidine |
Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity. |
| M20486
|
Dibenamine Hydrochloride |
Dibenamine is an irreversible blocker of α1 adrenoceptors. |
| M20449
|
Bevantolol hydrochloride |
Bevantolol hydrochloride is a cardioselective, beta adrenoceptor antagonist, devoid of intrinsic β sympathomimetic activity and with weak membrane-stabilizing and local anesthetic properties. |
| M20406
|
Amitraz |
Amitraz is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide. |
| M20391
|
Naftopidil DiHCl |
Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively. |
| M13901
|
Tulobuterol hydrochloride |
Tulobuterol hydrochloride (C-78) 是一种长效的 β2 肾上腺素受体 (β2-adrenoceptor) 激动剂，可减少慢性阻塞性肺疾病和支气管哮喘的发作频率。Tulobuterol hydrochloride 也是一种拟交感神经药，用作透皮贴剂，可增加正常的横膈膜肌肉力量。Tulobuterol hydrochloride 抑制鼻病毒 (rhinovirus) 复制并调节气道炎症。 |
| M13896
|
Norepinephrine hydrochloride |
Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride 是一种有效的肾上腺素能受体 (AR) 激动剂。Norepinephrine 可以激活 α1、α2、β1 受体。 |
| M13895
|
Metipranolol hydrochloride |
Metipranolol hydrochloride 是一种非选择性的 β 肾上腺素受体 (β adrenergic receptor) 阻断剂。可用于肺动脉高压及用于青光眼的研究。 |
| M13892
|
Methyldopa hydrate |
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate) 是一种 α-肾上腺素能激动剂 (对 α2-adrenergic receptors 有选择性)。Methyldopa hydrate 是一种前药，在中枢神经系统中被代谢 (α-Methylepinephrine)。 |
| M13889
|
CL 316243 |
CL316243 是一种高效的选择性 β3-肾上腺素受体 (β3-adrenoceptor) 激动剂，EC50 为 3 nM，但其对 β1/2-受体选择性却比较差。CL316243 是一种有效的脂肪细胞脂解刺激剂，可增加棕色脂肪组织的生热作用和代谢率。CL316243 具有有潜力用于肥胖症，糖尿病和尿失禁的相关研究。 |
| M13888
|
Bufuralol hydrochloride |
Bufuralol hydrochloride (Ro 3-4787 hydrochloride) 是一种有效的非选择性，具有口服活性的 β-肾上腺素受体 (β-adrenoreceptor) 拮抗剂，具有部分激动剂活性。Bufuralol hydrochloride 是一种 CYP2D6 探针的底物。 |
| M11289
|
Solabegron |
Solabegron (GW 427353) 是 β3 肾上腺素能受体 (β3-AR) 的选择性激动剂, 在中国仓鼠卵巢细胞中测得的 EC50 值为22 nM。可用于膀胱过度活跃和肠易激综合征的研究。 |
