找到约 14 条 “p-fin4” 相关结果 （用时 0.273 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M12841 | ChemBridge-7003154 | ChemBridge化合物-7003154 | Screening Compounds and Building Blocks |
| methyl N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoate (7003154) | |||
| ChemBridge特有类药化合物/先导化合物-7003154，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M50109 | ChemBridge-8928349 | ChemBridge化合物-8928349 | Screening Compounds and Building Blocks |
| [(3-methyl-4-nitro-1H-pyrazol-5-yl)sulfinyl]acetic acid (8928349) | |||
| ChemBridge特有类药化合物/先导化合物-8928349，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M52779 | p-fin4 | p-fin4 | GluR |
| p-fin4 是 STEP Phosphatase-GluA2 AMPA 受体相互作用的肽抑制剂，Ki 为 0.4 μM。 | |||
M11328
|
FINO2 | FINO2 | Ferroptosis |
| FINO2 是一种有效的 ferroptosis 诱导剂。FINO2 抑制 GPX4 活性。FINO2 是一种稳定的氧化剂，将铁氧化为氧化亚铁并在不同的 pH 值下保持稳定。FINO2 引起广泛的脂质过氧化。 | |||
| M25395
|
GSK1379725A | GSK1379725A | Epigenetic Reader Domain |
| AU1; AU-1 | |||
| GSK1379725A（AU1）是首个选择性的BPTF（Bromodomain PHD Finger Transcription Factor）配体，Kd值为2.8uM，对Brd4无结合活性。 | |||
| M7213 | Roxindole hydrochloride | Roxindole hydrochloride | Others |
| Roxindole hydrochloride is a dopamine D 2 autoreceptor agonist. Also has affinity for D 3, D 4, 5-HT 1A receptors and the 5-HT transporter. | |||
| M7479 | VUF 8430 dihydrobromide | VUF 8430 dihydrobromide | Others |
| VUF 8430 dihydrobromide is a potent, high affinity H 4 agonist. | |||
| M13433
|
NVP-DKY709 | NVP-DKY709 | Others |
| NVP-DKY709是一种IKZF2（IKAROS Family Zinc Finger 2）选择性分子胶降解剂。DKY709 处理人Jurkat T淋巴细胞16-20 小时后，IKZF2 会受到剂量依赖性的，选择性降解（Dmax=69%， DC50=11 nM），对 IKZF1 水平没有影响。DKY709还可降解IKZF4、SALL4。 | |||
| M15078
|
Recombinant Mouse Noggin/NOG (HEK293,C-6His) | 重组小鼠Noggin/NOG蛋白 (HEK293,C-6His) | Cytokines and Growth Factors |
| Noggin; Nog | |||
| Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession # : P97466. | |||
| M20515 | Emedastine | Emedastine | Histamine Receptor |
| Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM). | |||
| M20652 | JNJ-38877618 | JNJ-38877618 | c-Met |
| JNJ-38877618 (OMO-1) is a potent, highly selective, orally bioavailable MET kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant MET (2 and 3 nM IC50). | |||
| M20730
|
KGA-2727 | KGA-2727 | SGLT |
| KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models. | |||
| M20966
|
Ligandrol | Ligandrol | Androgen Receptor |
| LGD-4033 | |||
| Ligandrol (LGD-4033) is a novel nonsteroidal, oral selective androgen receptor modulator with high affinity (Ki of ∼1 nM) and selectivity. Ligandrol (LGD-4033) has demonstrated anabolic activity in the muscle, anti-resorptive and anabolic activity in bone, and robust selectivity for muscle versus prostate In animal models. | |||
| M24879 | Efineptakin alfa | Efineptakin alfa | IL Receptor/Related |
| NT-17 | |||
| Efineptakin alfa (NT-17) 是一种长效重组人 IL-7。 Efineptakin alfa 支持人和小鼠体内 CD4+ 和 CD8+ 细胞的增殖和存活。 Efineptakin alfa 可用于胶质母细胞瘤的研究。 | |||
