找到约 21 条 “Thrombin” 相关结果 （用时 0.106 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M9771
|
TRAP-6 | TRAP-6 | Peptides |
| Thrombin Receptor Activator Peptide 6; PAR-1 agonist peptide | |||
| TRAP-6 (Thrombin Receptor Activator Peptide 6) 是一种凝血酶受体激活肽，也是选择性的蛋白酶激活受体 1 (PAR1) 激动剂，TRAP-6 可以通过 PAR 1受体激活血小板并刺激血小板聚集。 | |||
| M9804
|
Thrombin | 凝血酶（来源于牛血浆） | Thrombopoietin/Thrombin |
| Thrombin凝血酶来源于牛血浆，是一种胰蛋白酶样别构丝氨酸蛋白酶。 | |||
| M9857
|
TRP-14 | 凝血酶受体激动剂；凝血酶受体活化因子肽 | Peptides |
| TRAP; SFLLRNPNDKYEPF; ThroMbin Receptor Agonist Peptide | |||
| Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe is a synthetic thrombin receptor agonist peptide. | |||
| M52506 | Thrombin receptor peptide ligand | Thrombin receptor peptide ligand | Thrombopoietin/Thrombin |
| Thrombin receptor peptide ligand 是一种凝血酶 (thrombin) 受体拮抗剂肽，可作为抗血栓剂。 | |||
| M52919 | Thrombin Receptor Activator for Peptide 5 (TRAP-5) | Thrombin Receptor Activator for Peptide 5 (TRAP-5) | PAR |
| Thrombin Receptor Activator for Peptide 5 (TRAP-5) 又叫作凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5) (Proteinase Activated Receptor 1 (1-5))，可用于冠心病的研究。 | |||
| M1674
|
BIBR 953 | 达比加群 | Thrombopoietin/Thrombin |
| Dabigatran, Pradaxa; BIBR 953ZW | |||
| Dabigatran (BIBR 953)是一种前体化合物，同时具有口服活性的，有效的非肽类凝血酶（Thrombin）抑制剂，IC50为9.3 nM。Dabigatran 能通过血浆和肝脏中的酯酶转化为活性形式达比加群酯，从而与凝血酶活性位点可逆结合，抑制凝血酶活性。 | |||
| M8210 | FR-171113 | FR-171113 | Others |
| FR171113 was the first non-peptide antagonist of the Protease Activated Receptor-1 (PAR1), also termed thrombin receptor. | |||
| M8658
|
Ximelagatran | 希美加群 | Thrombopoietin/Thrombin |
| Ximelagatran is orally active, selective and potent direct thrombin inhibitor. | |||
| M20396 | Argatroban | Argatroban | Thrombopoietin/Thrombin |
| MCI-9038 | |||
| Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. | |||
| M20440 | Benzamidine HCl | Benzamidine HCl | Serine/Threonine Protease |
| Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively. | |||
| M21312 | BAY 1217224 | BAY 1217224 | Thrombopoietin/Thrombin |
| BAY 1217224 是一种中性的 Thrombin 非前药抑制剂，具有良好的口服药代动力学。 | |||
| M28118 | Cyclotheonamide A | Cyclotheonamide A | Serine/Threonine Protease |
| Cyclotheonamide A 是一种丝氨酸蛋白酶 (serine protease) 抑制剂 (环状多肽)，可从 Theonella 属的海洋海绵中获得。Cyclotheonamide A 对 trypsin (Ki=0.023 µM) 和 streptokinase (Ki=0.035 µM) 显示强效的抑制活性，对人 α-thrombin (Ki=0.18 µM) 显示中等抑制活性。Cyclotheonamide A 可用于抗血栓的研究。 | |||
| M28647 | Napsagatran hydrate | Napsagatran hydrate | Thrombopoietin/Thrombin |
| Ro 46-6240 hydrate; Ro 46-6240/010 hydrate | |||
| Napsagatran hydrate 是一种新型的特异性凝血酶 (thrombin) 抑制剂。 | |||
| M42606 | Benzamidine hydrochloride hydrate | Benzamidine hydrochloride hydrate | Serine/Threonine Protease |
| Benzamidine (Benzenecarboximidamide) hydrochloride hydrate 是一种可逆的竞争性胰蛋白酶样丝氨酸蛋白酶 (trypsin-like serine proteases) 抑制剂，对 Tryptase、Trypsin、uPA、Factor Xa、Thrombin 和 tPA 的 Ki 值分别为 20、21、97、110、320 和 750 μM。 | |||
| M43869
|
Recombinant Human Integrin alpha V beta 3 Protein (HEK293, C-His) | 重组人Integrin alpha V beta 3 蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| ITGAV/ITGB3 | |||
| Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. | |||
| M50240 | Heparin sodium salt (MW 15kDa) | 肝素钠 (MW 15kDa) | Animal Modeling |
| Sodium heparin (MW 15kDa); Sodium heparinate (MW 15kDa) | |||
| Heparin sodium salt (MW 15kDa)是一种肝素聚合物，其分子量为 15kDa。Heparin sodium salt 是一种抗凝剂，能与抗凝血酶 III (ATIII) 可逆地结合，从而加快 ATIII 使 Thrombin factor IIa 和 factor Xa 失活的速度。Heparin sodium salt可用于实验动物血液采集和血浆制备，以及构建小鼠肠外营养模型。 | |||
| M51685 | β-Ala-Gly-Arg-pNA | β-Ala-Gly-Arg-pNA | Fluorescent Dye |
| β-Ala-Gly-Arg-pNA 是凝血酶 (thrombin) 的显色底物，pNA 在 405 nm 处有强吸光度。 | |||
| M52504 | Sar-Pro-Arg-pNA | Sar-Pro-Arg-pNA | Thrombopoietin/Thrombin |
| Sar-Pro-Arg-pNA 是一种 α-thrombin 的显色底物。 | |||
| M54606 | Desirudin | 地西卢定 | Thrombopoietin/Thrombin |
| CGP 39393 | |||
| Desirudin是一种凝血酶 (thrombin) 抑制剂，可抑制血栓形成和静脉淤血性血栓形成。Desirudin能用于血小板减少症或血小板功能障碍的相关研究。 | |||
| M55674
|
Recombinant Mouse Neuroserpin Protein (HEK293, C-His) | 重组小鼠Neuroserpin 蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| Serpini1 | |||
| Neuroserpin, also known as SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. | |||
| M56796 | Melagatran | Melagatran | Thrombopoietin/Thrombin |
| Melagatran 是具有口服活性的 thrombin 直接抑制剂，除凝血酶外，它与凝血级联反应中的任何其他酶或纤溶酶没有相互作用。Melagatran 的抗凝血酶作用不需要内源性辅因子，可能有助于减轻内毒素血症的某些破坏作用。 | |||
