找到约 39 条 “Serotonin” 相关结果 （用时 0.166 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M3004
|
Serotonin hydrochloride | 5-羟基色胺盐酸盐 | 5-HT Receptor |
| 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride | |||
| Serotonin hydrochloride 是一种单胺类神经递质和内源性5-HT受体激动剂。Serotonin hydrochloride 也是儿茶酚 O-甲基转移酶 (COMT) 的抑制剂，其 Ki 值为 44 μM。 | |||
| M6455 | Arachidonyl serotonin | 花生四烯羟色胺 | TRP Channel |
| Arachidonyl serotonin是一种脂肪酸酰胺水解酶（FAAH）抑制剂，以及TRPV1拮抗剂，作用于FAAH和TRPV1的IC50值分别为5.6 μM和37-40 nM。 | |||
| M7833 | Serotonin hydrogen maleate | 5-五羟色胺马来酸盐 | Others |
| Neurotransmitter. | |||
| M7841
|
Serotonin creatinine sulfate monohydrate | 5-五羟色胺肌酸酐硫酸盐 一水合物 | Metabolite/Endogenous Metabolite |
| Serotonin creatinine sulfate monohydrate stimulates neuronal production of catecholamine. Solutions should be freshly prepared. | |||
| M8401 | 2-Methylserotonin maleate | 2-Methylserotonin maleate | Others |
| 2-甲基5-羟色胺是5-HT3受体的选择性全激动剂。 | |||
| M13360
|
Serotonin | 5-羟色胺；血清胺 | 5-HT Receptor |
| 5-Hydroxytryptamine; 5-HT | |||
| Serotonin 是 CNS 中的单胺神经递质和内源性 5-HT 受体激动剂。Serotonin 也是儿茶酚 O-甲基转移酶 (COMT) 的抑制剂，其 Ki 值为 44 μM。Serotonin 也是动物的天然产物。 | |||
| M14392
|
N-Acetyl-5-hydroxytryptamine | N-Acetyl-5-hydroxytryptamine | Metabolite/Endogenous Metabolite |
| N-Acetylserotonin; Normelatonin; O-Demethylmelatonin | |||
| N-Acetyl-5-hydroxytryptamine 是褪黑激素前体，可有效地激活 TrkB 受体。 | |||
| M22314 | Eicosapentaenoyl Serotonin | Eicosapentaenoyl Serotonin | Others |
| Eicosapentaenoyl Serotonin | |||
| M39845 | N-(p-Coumaroyl) Serotonin | N-(p-Coumaroyl) Serotonin | VEGFR/PDGFR |
| N-(p-Coumaroyl) Serotonin 是一种从红花种子中分离出来的多酚，具有抗氧化、抗动脉粥样硬化和抗炎特性。N-(p-Coumaroyl) Serotonin 可降低肌浆网中 PDGF 诱导的对中 PDGFR 酪氨酸磷酸化和 Ca2+ 释放的作用。 | |||
| M39959
|
N-Feruloylserotonin | N-Feruloylserotonin | Others |
| N-Feruloylserotonin 是可从Carthamus tinctorius L. 中分离得到的一种血清素衍生物，具有抗氧化活性，有用于动脉粥样硬化和主动脉壁膨胀研究的潜能。 | |||
| M45090
|
2-Methyl-5-hydroxytryptamine | 2-甲基-5-羟色胺 | 5-HT Receptor |
| 2-Methyl-5-HT; 2-Methylserotonin; 2-Me-5-HT | |||
| 2-Methyl-5-hydroxytryptamine是一种有效的，选择性的 5-HT3 受体激动剂，可用于抑郁的相关研究。 | |||
| M57964 | NPEC-caged serotonin | NPEC-caged serotonin | Others |
| NPEC-caged serotonin | |||
| M58325
|
Oleoyl Serotonin | Oleoyl Serotonin | TRP Channel |
| Oleoyl Serotonin 是一种 TRPV1 拮抗剂，对于人 TRPV1 的 IC50 值为 2.57 μM。 | |||
| M1574
|
Iloperidone | 伊潘立酮 | 5-HT Receptor |
| HP873 | |||
| Iloperidone是一种dopamine (D2)/serotonin (5-HT2) receptor抑制剂，用于研究精神分裂症。 | |||
| M4887
|
Pardoprunox Hydrochloride | 盐酸帕多芦诺 | 5-HT Receptor |
| SLV-308 | |||
| Pardoprunox hydrochloride (DU-126891, SME-308)是一种有效的部分 dopamine D2 receptor 的激动剂，对应的pEC50值为8.0，也是诱导 [35S]GTPγS binding 的部分激动剂，对应的pEC50值为9.2，和 serotonin 5-HT1A receptor 的激动剂，pEC50值为6.3。 | |||
| M5861
|
Paroxetine HCl | 盐酸帕罗西汀 | 5-HT Receptor |
| BRL29060 hydrochloride; BRL29060A | |||
| Paroxetine HCl（盐酸帕罗西汀） 是一种高效的5-羟色胺（5-HT）再摄取 (serotonin-reuptake) 抑制剂（SSRIs），能抑制 GRK2 活性，IC50 值为 14 μM。可用于抑郁的相关研究。 | |||
| M5920
|
Ramosetron HCl | 盐酸雷莫司琼 | 5-HT Receptor |
| YM060 | |||
| Ramosetron Hydrochloride (盐酸雷莫司琼; YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. | |||
| M6064
|
Ziprasidone HCl | 盐酸齐拉西酮 | 5-HT Receptor |
| CP-88059 | |||
| Ziprasidone HCl 是一类有效的Dopamine 和 Serotonin (5-HT) Receptor的拮抗剂，可用于精神分裂症以及双向性障碍的相关研究。 | |||
| M6596 | Chlorphentermine hydrochloride | Chlorphentermine hydrochloride | Others |
| Chlorphentermine hydrochloride is a serotonin transporter substrate; appetite suppressant. | |||
| M7687 | CGS-12066 maleate salt | CGS-12066 maleate salt | Others |
| 5-HT1B serotonin receptor agonist. | |||
| M7799 | Norfluoxetine hydrochloride | 去甲氟西汀 | Others |
| Fluoxetine metabolite; more potent inhibitor of serotonin uptake than fluoxetine with a half-life in vivo of 5-7 days. | |||
| M7847 | Indatraline hydrochloride | Indatraline hydrochloride | Others |
| Potent inhibitor of dopamine, norepinephrine and serotonin uptake. | |||
| M7904 | Methiothepin mesylate salt | 马来酸甲硫替平 | Others |
| Metitepine mesylate; Ro 8-6837 mesylate | |||
| Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors. | |||
| M7935 | ML 10302 | ML 10302 | Others |
| Potent, selective 5-HT4 serotonin receptor agonist. | |||
| M7937 | MADAM dihydrochloride | MADAM dihydrochloride | Others |
| High affinity ligand for the serotonin transporter SERT. | |||
| M7977 | Octoclothepin maleate salt | Octoclothepin maleate salt | Others |
| Octoclothepin maleate salt is a D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist. | |||
| M8009 | Pipamperone dihydrochloride | Pipamperone dihydrochloride | Others |
| D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist; antipsychotic. | |||
| M8033 | Paroxetine hydrochloride hemihydrate | 盐酸帕罗西汀半水合物 | 5-HT Receptor |
| BRL29060 hydrochloride hemihydrate; BRL29060A hemihydrate | |||
| Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant. | |||
| M8036 | PF-04479745 | PF-04479745 | Others |
| PF-04479745 (PF-4479745) is a selective serotonin 5HT2C agonist. | |||
| M8051 | CP-53631 | CP-53631 | Others |
| CP-53631 is a selective serotonin reuptake inhibitor (SSRI); antidepressant. | |||
| M8148 | LY-165,163 | LY-165,163 | Others |
| Selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. | |||
| M8158 | SDZ-205,557 hydrochloride | SDZ-205,557 hydrochloride | Others |
| Potent, selective 5-HT4 serotonin receptor antagonist. | |||
| M8167 | SB-204070 hydrochloride | SB-204070 hydrochloride | Others |
| Selective 5-HT4 serotonin receptor antagonist. | |||
| M8175 | SF-22 | SF-22 | Others |
| Radioligand studies reveal that SF-22 also targets 5-HT2B and 5-HT6 serotonin receptors and dopamine transporter. | |||
| M8489 | Frovatriptan succinate monohydrate | 夫罗曲普坦琥珀酸盐水合物；罗曲普坦琥珀酸盐；夫罗曲坦琥珀酸；夫罗曲坦琥珀酸盐；琥珀酸夫罗曲坦一水合物 | Others |
| Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. | |||
| M8566
|
Eltoprazine hydrochloride | Eltoprazine hydrochloride | 5-HT Receptor |
| DU 28853 hydrochloride | |||
| Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. | |||
| M8576
|
LP-211 | LP-211 | Others |
| LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor with a Ki value of 0. | |||
| M13881
|
Ziprasidone | 齐拉西酮 | 5-HT Receptor |
| CP-88059 | |||
| Ziprasidone (CP-88059) 是一种 5-HT (serotonin) 和多巴胺受体 (dopamine receptor) 拮抗剂。Ziprasidone 对大鼠 (Ki: 3.4 nM) 和人 (2.5 nM) 5-HT1A，5-HT2A (0.42 nM) 和 dopamine D2 (4.8 nM) 受体有很高的亲和力。此外，Ziprasidone 还是一种去甲肾上腺素再摄取 (norepinephrine reuptake) 抑制剂。可用于精神类疾病的相关研究。 | |||
| M20437 | Perospirone hydrochloride | Perospirone hydrochloride | 5-HT Receptor |
| SM-9018 hydrochloride | |||
| Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
