找到约 8 条 “STING-IN-2” 相关结果 （用时 0.416 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M14125
|
STING-IN-2 | STING-IN-2 | STING |
| STING-IN-2 (C-170) 是一种有效且共价的 STING 抑制剂。STING-IN-2 有效抑制小鼠 STING (mmSTING) 和人类 STING (hsSTING)。STING-IN-2 可用于自身炎症性疾病的研究。 | |||
| M9084
|
STING-Inducer-1 | STING-Inducer-1 | STING |
| ML RR-S2 CDA | |||
| STING-Inducer-1 (ML RR-S2 CDA) 是一种STING（干扰素基因的刺激物）的诱导物。 | |||
M10459
|
MSA-2 | MSA-2 | STING |
| MSA2 | |||
| MSA-2 是一种口服非核苷类STING（干扰素基因刺激因子）激动剂，对人的 STING 的 WT和HAQ突变的 EC50 值分别为 8.3 μM和 24 μM。它通过激活STING信号通路发挥抗肿瘤作用，并且在酸性的肿瘤微环境中表现出更高的细胞渗透性和保留能力。MSA-2可诱导I型干扰素（如IFN-β）和其他促炎细胞因子（如IL-6、TNF-α）的分泌。 | |||
| M29290 | STING agonist-4 | STING agonist-4 | STING |
| STING agonist-4 是干扰素基因 (STING) 的受体激动剂的刺激剂，它的表观抑制常数 IC50 为 20 nM，STING agonist-4 是一种含两个对称相关的氨基苯并咪唑 (ABZI) 基的化合物。 | |||
| M29813 | PROTAC STING Degrader-1 | PROTAC STING Degrader-1 | STING |
| PROTAC STING Degrader-1 (Compound SP23) 是一种 STING PROTAC 降解剂，其 DC50 为 3.2 μM。PROTAC STING Degrader-1 具有抗炎活性。 | |||
| M42056 | STING agonist-8 dihydrochloride | STING agonist-8 dihydrochloride | STING |
| STING agonist-8 dihydrochloride (5-AB) 是一种有效 STING 激动剂，在 THP1-Dual KI-hSTING-R232 细胞中的 EC50 为 27 nM。 | |||
| M42058 | STING agonist-31 | STING agonist-31 | STING |
| STING agonist-31 是一种 STING 激动剂，对 h-STING 和 m-STING 的 EC50 值为 0.24 和 39.51 μM。 | |||
| M55364
|
Recombinant Mouse IL-22 (HEK293, C-mFc) | 重组小鼠IL-22 (HEK293, C-mFc) | Cytokines and Growth Factors |
| Interleukin-22 | |||
| Interleukin-22 (IL-22) is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. | |||
