找到约 10 条 “Retinoic acid” 相关结果 （用时 0.113 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M5715
|
Isotretinoin | 异维甲酸 | Others |
| 13-cis-Retinoic acid | |||
| Isotretinoin (13-cis-Retinoic acid，异维A酸) 是一种具有口服活性的，合成的类视黄醇和维生素A衍生物，可导致血清转氨酶水平升高，同时可通过结合并激活视磺酸核受体(RARs)，促进细胞分化和凋亡（Apoptosis）。Isotretinoin具有潜在的抗肿瘤活性和抗炎活性。 | |||
M5927
|
Retinoic acid | 视黄酸 | PPAR |
| ATRA; Tretinoin; Vitamin A acid; all-trans-Retinoic acid | |||
| Retinoic acid 是维生素A的代谢产物，在细胞生长，分化和器官发生中起重要作用。 Retinoic acid是RAR 核受体的天然激动剂，对RARα/β/γ的 IC50 为14 nM。 Retinoic acid与 PPARβ/δ 结合的 Kd 值为17 nM。Retinoic acid 可以通过激活视黄酸受体抑制转录因子 Nrf2。 | |||
| M9219
|
all-trans 4-Keto Retinoic Acid | 4-KETO全反式维甲酸 | Vitamin |
| all-trans-4-Oxoretinoic acid | |||
| all-trans 4-Keto Retinoic Acid是一种维生素A的活性代谢物，可通过作用核维甲酸受体 (RARs) 来诱导基因转录。 | |||
| M21365
|
9-cis-Retinoic Acid | 9-顺式视黄酸； 9-顺式维甲酸；阿利维A酸 | RAR/RXR |
| ALRT1057; Alitretinoin | |||
| 9-cis-Retinoic acid (ALRT1057)，维生素 A 的衍生物，是一种有效的 RAR/RXR 激动剂。9-cis-Retinoic acid 可诱导细胞凋亡 (apoptosis)，调节细胞周期并具有抗癌，抗炎和神经保护活性。 | |||
| M42599 | 4-Hydroxyretinoic acid | 4-Hydroxyretinoic acid | RAR/RXR |
| 4-Hydroxyretinoic acid (4-HRA) 是一种天然存在的类视黄酸衍生物，具有多种生物学作用。 | |||
| M7717 | CGP 52608 | CGP 52608 | Others |
| CGP 52608 is a specific activator of retinoic acid receptor-related orphan receptor α (RORA). | |||
| M7719
|
CD437 | CD437 | RAR/RXR |
| AHPN; Ro-472077 | |||
| CD437 是一个选择性视黄酸受体 (Retinoic Acid Receptor γ (RARγ)) 激动剂。 | |||
| M58448
|
Recombinant Human ALDH1A1 (E.coli, N-6His) | 重组人ALDH1A1 (E.coli, N-6His) | Cytokines and Growth Factors |
| Aldehyde Dehydrogenase Family 1 Member A1 | |||
| Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid. | |||
| M8652
|
CD1530 | CD1530 | Others |
| CD1530 is a potent and selective agonist of retinoic acid receptor RARγ with Kd values of 150, 1,500, and 2,750 nM for RARγ, RARβ, and RARα receptors, respectively. | |||
| M8773 | Liarozole dihydrochloride | Liarozole dihydrochloride | Others |
| Liarozole (R 75251, R75,251) is an orally active benzimidazole-based retinoic acid (RA) metabolism blocking agent (RAMBA) that targets multiple P450 enzymes, including aromatase (CYP19), 17-hydroxylase/17,20-lyas |
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